Exemplary embodiments are directed to an apparatus for manipulating one or more characteristics of air to be inhaled. The apparatus includes an outer housing including an outer surface, a hollow interior, and at least one opening formed in the outer housing and extending between the outer surface and the hollow interior. The apparatus includes a manipulation enclosure disposed within the hollow interior of the outer housing, the manipulation enclosure capable of receiving therein an air characteristic manipulation component. A substantially continuous channel is formed between the manipulation enclosure and the outer housing.

Respiratory devices and methods for their manufacture and use are disclosed. The device features a resiliently deformable element configured to form a perimeter seal with the inner nostril wall and to swab the distal portion of the internal nostril region with a disinfectant during device installation. A first filter stage includes a first filter layer characterized by first geometric convolutions and a first MPPS1 value; and a second filter stage includes a second filter layer characterized by second geometric convolutions and a second MPPS2 value.

Devices and methods of inhibiting the inhalation of particulates using a resiliently deformable filter packaged in a sealed envelope containing a liquid medium. The method includes opening the sealed package to thereby expose the filter to ambient air; removing the filter from the package; inserting the filter into a distal region of a nostril; and urging the filter from the distal region to a proximal region of the nostril while simultaneously swabbing the distal region with the liquid disinfectant. The filter includes: an initial stage characterized by a first pore size; an intermediate stage characterized by a second pore size; and a final stage characterized by a third pore size, wherein the third pore size is a smaller than the first and second pore sizes.

Respiratory devices and methods for their manufacture and use are disclosed. The device features a resiliently deformable element configured to form a perimeter seal with the inner nostril wall and to swab the distal portion of the internal nostril region with a disinfectant during device installation. A first filter stage includes a first filter layer characterized by first geometric convolutions and a first MPPS1 value; and a second filter stage includes a second filter layer characterized by second geometric convolutions and a second MPPS2 value.

A clip device is provided, which is configured to removably attach to a body part of a human or animal user. The clip is of an elastomeric, silicone-based material, and the material is configured to absorb an oil to infuse the clip with the oil. The oil is to be applied to a user through the clip when the clip is attached to the body part of the user. In some instances, the clip device is adapted to connect to the nose of the user by way of the user's nostrils.

A method of increasing eustachian tube patency in human patients is disclosed wherein a eustachian tube targeting nasal administration device is utilized to deliver a surfactant/propellant mixture to the nasopharyngeal stoma of the auditory tube. The targeting capability of the administration device obviates the need for a spreading agent that would otherwise be required to enable at least a portion of surfactant to reach the eustachian tube orifice. More specifically, the non-targeting, indiscriminate delivery provided by nasal administration devices of the past required surfactant to spread over non-targeted tissue it was inadvertently applied to in order to reach the eustachian tube stoma. In addition, a method for treatment of otitis media is disclosed utilizing, in some preferred embodiments, a therapeutically active agent.

A compact single-nostril atomizer for the inhalation of active ingredients is presented. The atomizer has an elastic U-shaped housing, a first end of which can be introduced into the nostril and a second end of which is formed as a clamping element. In the first end of the housing a cavity for receiving a reservoir is disposed. A reservoir containing an active ingredient can be inserted into the cavity.

A veterinary subject intranasal administration device, and associated systems and methods, are disclosed. The veterinary subject intranasal administration device can include a first support member portion including a septum interface portion sized for insertion into a nasal passage of the veterinary subject; an actuation mechanism connected to the first support member portion; and a fluid conduit having a distal end opposite a supported end, the distal end sized for insertion into the nasal passage of the veterinary subject, the fluid conduit being flexible and configured to receive fluid from a fluid source and discharge the fluid through the distal end into the nasal passage, the distal end of the fluid conduit being unsupported and movable relative to the septum interface portion.

A device for inhibiting at least partially the sense of smell including a solid body is provided for having a main extension along a main plane in which it has a main shape including: an upper portion extending mainly in the longitudinal direction and including a first upper edge substantially flat and aligned with the longitudinal direction, a lower portion protruding at least partially in said vertical direction and downwards, a rear portion extending diagonally in relation to the longitudinal and vertical directions and including a second upper edge in direct contact with the first upper edge and extending in a direction inclined at an angle of between 20 and 70 with respect to the longitudinal direction; the first upper edge extends, in addition, in the transverse direction, more than the remaining part of the solid body.

A nasal device for filtering breathing air comprises an elongated support member, and two rounded holder members, each arranged at a respective end of the elongated support member. The holder members are adapted to be inserted into a nostril with a distal end directed into the nostril, and a proximal end adjacent the nostril openings. The holder members comprise a bell-shaped cross-section in at least one plane in a distal-proximal extension.