Methods and systems for delivery of pulsated air to a user using a device including a flow generator to generate a continuous air flow, a first actuator comprising a pulsated flow delivery mechanism configured to generate a pulsated air flow from the continuous air flow based on a pre-determined duty cycle to vary a frequency of the pulsated air flow, a user interface configured to generate and deliver vortices of pulsated air to the user at the frequency of the pulsated air flow, and a set of tubing to couple the flow generator, the first actuator, and the user interface.

Systems and methods are configured to inexsufflate a subject and provide cough-by-cough feedback during treatment and/or therapy of the subject. Through sensors that are included in the systems, various gas and/or respiratory parameters maybe measured and/or determined in real-time, such as, for example, peak cough flow and/or inspiratory tidal volume.

An inspiratory resistor valve system (IRV) to regulate intrathoracic pressure during positive pressure breathing, spontaneous inspirations, and CPR may include an inspiratory port. The IRV system may include patient port. The IRV system may include a separate expiratory port. The IRV may include a plurality of atmospheric pressure sensitive valves. The plurality of atmospheric pressure sensitive valves may isolate the expiratory port and the inspiratory port from one another.

The present disclosure describes a ventilator. The ventilator includes tubing configured to receive an input gas and a flow outlet airline in fluid communication with the tubing. The flow outlet airline includes an airline outlet, and the flow outlet airline is configured to supply an output gas to a user via the airline outlet. The ventilator includes an aerosol generator in fluid communication with the flow outlet airline. The aerosol generator is configured to receive an input liquid through an inlet tube and transform the liquid input into an aerosol. The ventilator further includes a breath detection airline including an airline inlet, wherein the airline inlet is separated from the airline outlet of the flow outlet airline, and configured to receive breathing gas from the user during exhalation by the user via the airline inlet. A method of supplying respiratory gas containing an aerosol is disclosed.

The present invention is directed to an assembly and method of use thereof for reducing microbial load in an airway of a patient. The assembly includes a miniature vacuum unit. The miniature vacuum unit includes a housing, at least one air inlet configured in the housing for air intake; a vacuum motor for sucking the air through the at least one air inlet; vents configured in the housing for blowing the sucked air out of the housing, a filter media covering inner side of the vents, such as the sucked air passes through the filter media, the filter media configured to retain microbes suspended in the sucked air; and at least one suction tube. The suction tube is having a proximal end and a distal end, the proximal end of the at least one suction tube configured to sealably and releasably coupled to the at least one air inlet, a plurality of apertures configured in the wall of the suction tube near its distal end. The suction tube configured to be positioned within the mouth of the patient.

A passive valve for use as a fixed leak valve. The valve includes a body having an internal chamber, first and second body ports in fluid communication with the chamber with the first port configured for fluid communication with a patient connection and the second body port configured for fluid communication with a ventilator, a body passageway in fluid communication with the chamber and with ambient air exterior of the body, and a check valve seal positioned to seal the body passageway to permit the flow of gas within the chamber through the body passageway to the exterior of the body and to prevent the flow of ambient air exterior of the body through the body passageway into the chamber. In alternative embodiments, the valve is incorporated into the patient connection or constructed as a separate part connectable to the patient connection.

A synchronized automated bronchial lavage aspiration apparatus synchronizes with ventilator inspiration and expiration cycles to clear a patient's airway of stagnant secretion automatically. Synchronized and automatic instillation of saline prior to aspiration suppresses bacteria in the airway and suctioning during exhalation drains the airway of sputum.

A portable medical ventilator using pulse flow from an oxygen concentrator to gain higher oxygen concentration includes a positive pressure source to deliver pressurized air to the patient and a negative pressure source to trigger the oxygen concentrator. A patient circuit attached to a patient interface mask connects the ventilator to the patient. The ventilator includes a controller module that is configured to generate a signal to the negative pressure device to trigger the concentrator to initiate one or more pulses of oxygen from the oxygen concentrator. The oxygen pulses are delivered to the patient interface directly through multi-tube or a multi lumen patient circuit. The oxygen does not mix with air in the ventilator or in the patient circuit and bypasses the leaks in the patient circuit and/or patient interface.

A respiratory ventilator device is described herein. The respiratory ventilator device includes an inhaled air assembly, an exhaled air assembly, and a control system operatively coupled to the inhaled air assembly and the exhaled air assembly. The inhaled air assembly is coupled to a patient respiratory circuit and configured to channel a volume of inhalation air to the patient's lungs to assist in patient inhalation. The exhaled air assembly is coupled to the patient respiratory circuit and configured to remove air from the patient's lungs to assist in a patient exhalation. The control system is configured to operate the respiratory ventilator system in an inhalation mode and an exhalation mode.

A device for placing a lung in a variety of different inflation states using positive air pressure. An exemplary device includes a housing and an air supply component. The housing includes a platform receives at least one of a synthetic lung or a real lung. The platform is at the same air pressure as a surrounding environment. The air supply component is located within the one or more internal cavities of the housing. The air supply component inflates the synthetic lung or the real lung with positive pressure.