Cartridges for vaporizer devices are provided. In one exemplary embodiment, the cartridge can include first and second storage chambers each configured to hold a respective fraction of a vaporizable material, a vaporization chamber that includes an elongate member that is in fluid communication with the first and second storage chambers and configured to receive the vaporizable material, a magnetic element disposed within a channel of the elongate member, and a conductive element that is configured to generate a first motive force to drive the magnetic element between first and second positions and further configured to substantially vaporize the vaporizable material within the elongate member. Vaporizer devices are also provided.

Apparatus, systems and methods are described, such as for providing, or controlling mechanical ventilation provided to, a patient. A controller may control a gas delivery system to deliver gas to the patient according to a FiO2 setting and a PEEP setting. The controller may adjust the FiO2 setting to an updated FiO2 setting based at least in part on a determined oxygen concentration of the patient's blood and may update the PEEP setting based at least in part on the updated FiO2 setting. Furthermore, the controller may update the PEEP setting based at least in part on the updated FiO2 setting and the current PEEP setting. An updated PEEP setting may be based at least in part on PEEP change eligibility rules and PEEP selection rules. The FiO2 setting may be adjusted so as to relatively rapidly increase the FiO2 setting in response to a rapidly decreasing patient SpO2.

A lung simulator for partial simulation of functions of a lung, comprising at least one gas loop which is connected to a ventilator which is configured to convey a breathing gas into and/or out of the gas loop at least temporarily. The lung simulator comprises at least one device for setting the O2 concentration of the breathing gas in the gas loop, at least one device for setting the CO2 concentration of the breathing gas in the gas loop and at least one device for simulating a mechanical lung movement.

The invention comprises a method of operating a breathing apparatus comprising measuring a baseline breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, varying the flow rate provided by the breathing apparatus, measuring a current breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, comparing the baseline and current breath flow parameters, and altering operation of the breathing apparatus based on the comparison. The invention also comprises a breathing apparatus that implements the above method.

A resuscitation device is disclosed that includes a pump having a cylinder with a gas inlet and a gas outlet, a piston to travel in the cylinder, and a valve. The valve is configured to allow gas to be displaced into the cylinder through the gas inlet during a first stroke direction and second stroke direction of the piston in the cylinder, and for allowing gas to be displaced through the gas outlet during an opposite of the first stroke direction and second stroke direction of the piston in the cylinder; a motor, selected from one of a stepper motor, a feedback motor, a stepper motor with feedback, and a linear motor, connected to the piston to move the piston in the cylinder; and a patient interface in fluid connection with the pump to receive gas via the gas outlet and to deliver the gas to a patient.

The invention comprises a method of operating a breathing apparatus comprising measuring a baseline breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, varying the flow rate provided by the breathing apparatus, measuring a current breath flow parameter being respiratory rate and/or tidal volume or a parameter derived therefrom, comparing the baseline and current breath flow parameters, and altering operation of the breathing apparatus based on the comparison. The invention also comprises a breathing apparatus that implements the above method.

The present disclosure pertains to a system configured to amplify the pressure and/or flow rate of a pressurized flow of breathable gas by entraining oxygen gas and/or ambient air with an air amplifier and a venturi valve at or near a blending gas source, distally (e.g., remotely) from an interface appliance of a subject interface (e.g., away from the face of the subject) to reduce noise from the system heard by the subject. The system is configured to provide this pressure support and/or ventilation with oxygen therapy. The system is configured to deliver ventilatory and/or pressure support with oxygen therapy while decreasing output requirements of the blending gas source and/or pressure generator.

Systems and methods provide respiratory therapy to a subject through a pressurized flow of breathable gas. Timing and other characteristics of pressure and flow levels provided during inhalations and exhalations are adjusted in order to increase the volumetric rate of expulsion of CO2.

This invention relates to a breath indicator for providing an indication of an inhalation and/or exhalation state of a user. Said breath indicator comprising a body comprising a gas sampling portion configured for receipt of a user's inhalation and/or exhalation gases, and an indicator portion. Said gas sampling portion in fluid communication with said indicator portion. Said indicator portion comprising at least a first region and at least a second region, the first region comprising a gas parameter detecting material capable of changing between an initial visual state and a subsequent visual state indicative of detection of a gas parameter of inhalation and/or exhalation gases of said user; and wherein said initial visual state and/or said subsequent visual state of the first region visually contrasts with a visual state of at least said second region.

An aerosol provision system comprises a heating element for generating an aerosol from a source liquid and control circuitry for controlling a supply of electrical power from a power supply to the heating element. The control circuitry is configured to measure an indication of a derivative of an electrical characteristic of the heating element with respect to time. Based on the measured time derivative, the control circuitry is configured to determine whether or not a fault condition has arisen for the electronic aerosol provision system. The overall change in the electrical characteristic for the heating element caused by the localized heating may be small and so difficult to reliably identify, but the rate at which the change occurs can be expected to be relatively high, such that the time derivative of the local characteristic is a more reliable indicator of occurrence of the fault condition.