Provided is an exacerbation prediction device equipped with a respiration sensing means of continuously sensing respiration data of a patient, a calculation means of calculating stable respiration data that are respiration data during a condition in which a respiratory rate is lowered and stable for a certain period of time from the sensed continuous respiration data of the patient, and a prediction means of predicting occurrence of an acute exacerbation in the patient in accordance with the stable respiration data calculated during a certain period of time.

Product manifolds for use with portable oxygen concentrators and portable oxygen concentrators including such product manifolds. A product manifold for use with a portable oxygen concentrator includes a first product port, a second product port, an accumulator port, an output port, and a flow path. The flow path operatively coupling each of the first product port, the second product port, the accumulator port, and the output port to one another. The product manifold includes a plurality of control ports. Each of the control ports fluidly coupling the flow path. The product manifold includes a first orifice disposed in a first portion of the flow path; a second orifice disposed in a second portion of the flow path; and a third orifice disposed in a third portion of the flow path. Each of the first orifice, the second orifice, and the third orifice being formed by an electrical forming process and having a thickness of between about 0.0025 inches and about 0.004 inches.

A respiratory device can include an oxygen generator and a ventilator. The oxygen generator can include a first inlet to ambient air, a vacuum or pressure swing oxygen generating system in fluid communication with the first inlet, a first fluid pathway, and a first outlet. The ventilator can include a second inlet to ambient air and a blower in fluid communication with the second inlet to draw ambient air. The ventilator can include a third inlet in fluid communication with the first fluid pathway upstream of the first outlet. The blower can also be in fluid communication with the second inlet to draw at least some of the extracted oxygen. The ventilator can also include a second outlet in fluid communication with the blower to dispense a mixture of the ambient air and the extracted oxygen to the user.

A monitoring device (1) for a system for generating medical compressed air includes a measured air line (3) removing compressed air from a compressed air supply line downstream of a compressed air conditioning unit. A sensor (2) generates a measured signal as a function of a property of the compressed air fed through the measured air line. A humidifier (8) humidifies the compressed air upstream of the sensor. An output unit (12) outputs information about the property of the compressed air to a user on the basis of the measured signal. A tap (4) removes compressed air and an actuator (5) changes a volume flow and/or mass flow of the compressed air, which volume flow and/or mass flow prevails in the measured air line. The actuator is inserted into the tap in a measuring mode and is removed from the tap in a compressed air removal mode.

A stand-alone chamber or multi-chamber inhalation system has at least two alternative vaporized test liquid supply systems for passive or self-administered delivery of vaporized test fluid and air to one or more test chambers, which can be passive or restraint chambers, based on operator selection of delivery on and off times in a passive mode or actuation of an actuator in the chamber by a test animal in a self-administered mode. In one case, a multiple inhalation chamber system has two or more separate test fluid delivery systems and provides options for selective passive uniform drug delivery to multiple chambers or selective delivery of two or more different drugs to different groups of chambers from different delivery systems so that two different drugs or different concentrations of delivered drugs can be tested simultaneously.

This disclosure describes systems and methods for providing a high pressure controlled proportional assist ventilation breath type during ventilation of a patient. The disclosure describes a novel breath type that reduces ventilator support (or a percent support setting) based on the occurrence of a predetermined number of high pressure alarms.

Devices and methods for allowing for improved assisted ventilation of a patient. The methods and devices provide a number of benefits over conventional approaches for assisted ventilation. For example, the methods and devices described herein permit blind insertion of a device that can allow ventilation regardless of whether the device is positioned within a trachea or an esophagus. In addition, the methods and device allow for timed delivery of ventilations based on a condition of a thoracic cavity to increase the amount and efficiency of blood flow during a resuscitation procedure.

An automatic control system for a manual mechanical ventilation device comprising a servomotor, an actuator and a stepper cylinder adapted to compress the mechanical ventilation device in response to signals sent by a controller. The controller is further connected to at least one flow sensor and one pressure sensor and has a human-machine interface for the insertion of pressure and oxygen flow output values to be received by a patient.

A ventilator includes a bidirectional breath detection airline and a flow outlet airline. The flow outlet airline includes an airline outlet. The flow outlet airline is configured to be connected to an invasive ventilator circuit or a noninvasive ventilator circuit. The breath detection airline includes airline inlet. The airline inlet is separated from the airline outlet of the flow outlet airline. The ventilator further includes a pressure sensor in direct fluid communication with the breath detection airline. The pressure sensor is configured to measure breathing pressure from the user and generate sensor data indicative of breathing by the user. The ventilator further includes a controller in electronic communication with the pressure sensor. The controller is programmed to detect the breathing by the user based on the sensor data received from the pressure sensor.

Devices and methods for allowing for improved assisted ventilation of a patient. The methods and devices provide a number of benefits over conventional approaches for assisted ventilation. For example, the methods and devices described herein permit blind insertion of a device that can allow ventilation regardless of whether the device is positioned within a trachea or an esophagus. In addition, the methods and device allow for timed delivery of ventilations based on a condition of a thoracic cavity to increase the amount and efficiency of blood flow during a resuscitation procedure.