A ventilator, for the automated ventilation of a patient, includes a breathing gas delivery unit, at least one volume flow sensor for detecting a volume flow of the breathing gas, at least one breathing gas sensor for detecting a carbon dioxide concentration in the breathing gas, at least one pressure sensor for detecting a pressure of the breathing gas, as well as at least one computer. The computer is configured to actuate the breathing gas delivery unit as a function of the detected pressure and of a preset desired pressure value. The computer is further configured to perform an adaptation of the desired pressure value and an adaptation of a ventilation rate as a function of the detected volume flow and as a function of the detected carbon dioxide concentration.

The invention relates to a fluid delivery device (2, 2) for delivering a fluid into a human or animal body. The fluid delivery device (2, 2) comprises a fluid chamber (4, 4) for receiving a fluid, an oscillator (6, 6) for imparting oscillations to at least a portion of the fluid and a control for controlling the oscillator (6, 6). The oscillator (6, 6) comprises a vibrator (8, 8) and a resonator (10, 10). The resonator (10, 10) has a main body (12, 12), defining an interior volume (14, 14), and a neck (16, 16). The neck (16, 16) is connected to the main body (12, 12) and in fluid communication with the interior volume (14, 14). The vibrator (8, 8) is configured to impart vibrations to the resonator (10, 10). The control is configured to control operation of the vibrator (8, 8) so as to impart vibrations to the resonator (10, 10) at a resonance frequency of the resonator (10, 10) or at a frequency which is within 20% of a resonance frequency of the resonator (10, 10). The invention further relates to a method of operating the fluid delivery device (2, 2).

Liquid ventilator and methods integrating the concept of total liquid ventilation (TLV) using liquid volumes below functional residual capacity (FRC) of mammal's lungs are disclosed. Beyond the automatization of the whole process, the technology has been up-scaled to confirm that TLV at residual volumes below FRC can provide a safe procedure while enabling the full potential of TLV in a mammal such as humans or adult-sized animals. Such tidal liquid ventilation strongly differs from the previously known TLV approach, opening promising perspectives for a safer clinical translation. Also disclosed are apparatus and method for safe and fast induction of hypothermia during liquid ventilation of a mammal.

The present disclosure pertains to a method and system configured for cough synchronization in a mechanical insufflation-exsufflation system. The system is configured to synchronize (712) the transition from an insufflation mode to an exsufflation mode to a patient initiated cough by detecting cough effort of the patient e.g. at the end of the insufflation phase. The detection of cough effort of the patient is based on one or more parameters associated with gas in the system. Upon detecting that the patient is initiating a cough, the system automatically switches the insufflation mode to the exsufflation mode to assist the patient to generate an effective cough.

In some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters.

Embodiments of the present invention provide systems and methods for delivering respiratory treatment to a patient. For example, a treatment system may include a mechanism for delivering a positive pressure breath to a patient, and one or more limb flow control assemblies which modulate gas flow to and from the patient. Exemplary treatment techniques are embodied in anesthesia machines, mechanical ventilators, and manual ventilators.

A breathing assistance apparatus includes an inner volumetric member pressurizable from a first pressure to a second pressure and an outer volumetric member surrounding at least a portion of the inner expandable volumetric member. The inner volumetric member pressurizes the outer volumetric member as the inner volumetric member is pressurized from the first pressure to the second pressure. In another embodiment, a breathing assistance apparatus includes exhalation and inhalation chambers with respective biasing members providing for the exhalation chamber to apply a pressure to the inhalation chamber and thereby provide assisted inhalation. Methods for assisting breathing are also provided.

The method and system according to preferred embodiments of the present invention allows an effective breath-synchronized delivery of atomized liquid medicament (e.g. a pulmonary surfactant) to the patient's lungs. According to a preferred embodiment, the method of the present invention provides an efficient delivery of the aerosol medicament, controlling the behavior of the infusion pump to make the rising and falling time faster even though the intrinsic time constant of the system is long. Additionally, in an embodiment of the present invention, at the same time the information about the breathing activity contained either directly on the surfactant line or stored in the controller action can be used to extrapolate the breathing pattern.

One or more sensors are configured for detection of characteristics of moving objects and living subjects for human identification or authentication. One or more processors, such as in a system of sensors or that control a sensor, may be configured to process signals from the one or more sensors to identify a person. The processing may include evaluating features from the signals such as breathing rate, respiration depth, degree of movement and heart rate etc. The sensors may be radio frequency non-contact sensors with automated detection control to change detection control parameters based on the identification of living beings, such as to avoid sensor interference.

Manual resuscitators, ventilation control assemblies, and methods suitable for delivering a volume-controlled tidal volume of air to a patient's lungs. Such a resuscitator has a piston that pushes a selected volume of air out of a ventilation chamber of a cylinder in response to pressurized gases being introduced into an actuation chamber of the cylinder. A volume adjuster adjusts the maximum tidal volume of patient air that the piston pushes out of the ventilation chamber by adjusting the maximum length of the piston stroke in the cylinder. The volume adjuster may have a bypass mode that allows the manual resuscitator to operate without volume control. The manual adjuster may also be pressure regulated by one or more pressure regulation valves.