A patient interface may include a dual chamber cushion assembly having a nasal chamber and an oral chamber. The nasal chamber may be arranged to deliver pressurized breathable gas to a patients nasal passages, and the oral chamber may be arranged to deliver pressurized breathable gas to the patients oral passages. The nasal chamber may be pressurized to a different level than an oral chamber to promote nasal breathing. An air passage may fluidly connect the nasal chamber and the oral chamber so that pressurized breathable gas may flow from the nasal chamber to the oral chamber.

Aspects of the present technology comprise a positioning and stabilising structure to hold a seal-forming structure in a therapeutically effective position on a head of a patient. The seal-forming structure may be constructed and arranged to form a seal with a region of the patients face surrounding an entrance to the patients airways for sealed delivery of a flow of air at a therapeutic pressure of at least 4 cmH2O with respect to ambient air pressure throughout the patients respiratory cycle in use. The positioning and stabilising structure may comprise a front hoop arranged to contact, in use, at least a region of the patients head superior to an otobasion superior of the patients head and a rear strap. The positioning and stabilising structure may comprise an adjustment mechanism for adjustment of the front hoop and the rear strap relative to the patients head, the adjustment mechanism being arranged in a single operation to adjust both the front hoop and rear strap to enable the positioning and stabilising structure to fit different size heads.

Described is a system including an air pressure supply arrangement, a sensor and a titration device. The air pressure supply arrangement provides air pressure to a patient's airways. The sensor detects input data corresponding to a patient's breathing patterns of a plurality of breaths. The titration device receives and analyzes the input data to determine existence of breathing disorder and corresponding characteristics. The titration device generates output data for adjusting the air pressure supplied to the patient as a function of an index of abnormal respiratory events included in the input data.

A nasal cannula includes a first tube, a second tube, a nasal connector tube, and a flow splitter. The nasal tube has first and second ends, the first end connected to a distal end of the first tube, the second end connected to a distal end of the second tube. First and second nasal prongs extend from and are fluidly coupled to the nasal connector tube. The flow splitter has an input and first and second outputs. The first output of the flow splitter is connected to a proximal end of the first tube. The second output of the flow splitter is connected to a proximal end of the second tube.

A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

Devices, systems, and methods are disclosed which permit ventilation therapy concurrent with humidity and aerosol drug delivery. Exemplary mixer-heaters employ alternating actuation of humidity and drug nebulizers and may use a single constant power setting for the heating section while keeping a controlled outlet temperature over the course of treatment.

A patient has a cushion forming at least part of a plenum chamber pressurizable to a therapeutic pressure. The cushion includes a seal-forming structure to form a seal with a region of a patient's face surrounding the entrance to the patient's nares; a positioning and stabilising structure to provide a force to hold the seal-forming structure in a therapeutically effective position on a patient's head, the positioning and stabilizing structure comprising a first and second headgear sections each adapted to extend towards the cushion from the rear of the patient's head, the first headgear section comprising a hollow tube configured to convey pressurized gas at the therapeutic pressure from the rear or crown of the patient's head to the cushion, the second headgear section comprising a strap.

A patient interface a positioning and stabilising structure, which includes a gas delivery tube with a tube wall that has an interior passage for flow of pressurized air. A portion of the tube wall includes a patient contacting portion and a non-patient contacting portion. The patient contacting portion includes a layer of textile material or foam material configured to lie against the patient's head. At least a section of the non-patient contacting portion includes of a transparent and/or translucent material. The layer of textile material or foam material is bonded to the transparent and/or translucent material so that the tube wall is formed as a one piece construction. A plane extends generally transverse to longitudinal axis contains both (1) the textile material or foam material and (2) the transparent and/or translucent material, so that the patient may view the interior passage along a transverse axis extending through the plane.

A respiratory interface assembly includes a patient interface, such as a nasal mask, and a headgear arrangement. The headgear arrangement can have one or more semi-rigid straps, which can be a composite construction of an outer fabric and a plastic core. The outer fabric can be knitted. The headgear arrangement can include a composite rear portion having an upper strap and lower strap, which are configured to be adjustable relative to one another.

A nasal prong comprising a tube configured to be partially placed in a nasal passage of a patient, the tube having a first end, a second end, and an intermediate portion, and a lumen extending therebetween. The first end having an elongated opening configured to face supero-medially within the nasal passage, wherein airflow out of the elongated opening is directed superiorly and posteriorly within the nasal cavity, above the inferior concha, around the middle concha, and towards the roof of the nose. The intermediate portion of the tube having a bend that keeps the nasal prong on a floor of the nasal passage at and/or near the outer edge of a nostril.