Systems and methods are provided for aerosolizing and delivering therapeutic substances in an electronic aerosol delivery device with airflow regulation. Calibrated airflow resistance settings enable adjustment and control of flow velocity and or flow volume of air, aerosolized air, and or entrained aerosol particles, through the device, for optimal aerosol delivery among diverse conditions and applications.

A coated anesthetic container for an anesthetic dispenser includes an anesthetic tank, which is capable of receiving a liquid anesthetic (Nm), as well as a refill unit for refilling liquid anesthetic (Nm). The anesthetic tank includes a wall and a coating on the inner surface of the wall. A wall of the refill unit is connected in a fluid-tight manner to the wall of the anesthetic tank. A coating is applied at least to the inner surface of the wall of the anesthetic tank. This coating is made of an alloy of nickel and phosphorus. The nickel portion is in a range of 80 wt.% to 97 wt.%, and the phosphorus portion is in a range of 3 wt.% to 15 wt.%. A process is provided for manufacturing such an anesthetic container.

A system and method for airflow control of pressurized air delivery, and more specifically, but not exclusively, to a robust valve assembly for use in a positive airway pressure treatment (PAPT) system and method to improve speech during treatment.

A flow interrupter for gas flow delivered by a delivery conduit in a respiratory treatment system permits temporary interruption of flow in the conduit. Typically, the apparatus has a passage to conduct a breathable gas. The passage traverses through a flexible wall such as a stretchable sleeve. The flexible wall may include a first and second ends. A manipulator may be attached to the flexible wall. The flexible wall sleeve may be adapted to twistably collapse between the first and second ends so as to reduce the passage of the channel by operation of the manipulator. The flow interrupter may be formed with a swivel and operation of the sleeve may be implemented by rotation of the swivel. Sufficient rotation of such a swivel may form a vortex closure of material to close the channel. Release of the manipulator may then permit unwinding of the vortex closure, re-opening the channel.

Start-up protocols for a device and method for administering NO is described.

An expiratory, vibratory therapy device (100, 200 300, 400) includes a compliance meter (104, 204, 304, 404) having a cylinder (110, 210, 310, 410) with a piston (111, 211, 411) movable along its length. The piston is urged by a spring (116, 226) to one end of the cylinder. The opposite end of the cylinder has an air inlet (120, 123, 219) normally closed by a springloaded occluder (129). The occluder (129) is moved to open the air inlet when the patient exhales in the prescribed manner. This allows some air to enter the cylinder and enables the piston to be displaced. The piston is coupled to a flag (106, 206, 306, 406) visible to the patient. When the correct number of prescribed breaths have been made the piston displaces the flag to indicate completion of the therapy.

A respiratory treatment device for the combined administration of respiratory muscle training (“RMT”) and oscillating positive expiratory pressure (“OPEP”) therapy, and administration of RMT using pressure threshold resistors and flow resistors with respiratory treatment devices, such as OPEP devices.

A tracheal connector is connected to a respiratory gas generator and a tracheal tube. The tracheal connector includes a tracheal connector body connected to the tracheal tube, a connector tube connected to the tracheal connector body and the respiratory gas generator, and a restriction mechanism configured to narrow a respiratory gas flow path configured to allow the respiratory gas to flow therein. The tracheal connector body includes a tracheal port connected to the tracheal tube, an exhaust port facing the tracheal port and configured to discharge at least expired air of the subject, and a respiratory port connected to the connector tube. The restriction mechanism is provided on the respiratory gas flow path between the respiratory port and the tracheal port.

A respiration appliance (10) is configured to entrain the breathing of the subject. The breathing of the subject is entrained to modulate the autonomic nervous system of the subject to decrease sympathetic nerve activity and/or to reduce sympathetic/parasympathetic balance in order to provide relaxation to the subject. The respiration appliance (10) restricts the exhalation of the subject, while permitting substantially unencumbered inhalation, to impact the breathing of the subject in a manner that enhances relaxation.

According to one aspect, there is provided a device (4) for providing supplemental oxygen to a subject (8), the device (4) comprising a subject interface (10) through which the subject (8) can inhale; a container (12) that has a first outlet (18) connected to the subject interface (10) to allow gas with an elevated oxygen level stored in the container (12) to be inhaled by the subject (8), a first inlet (24), and a material (15) for removing a specific gas from air passing through the container (12) to increase the oxygen content of the air passing through the container (12); and an air blower (14) that is connected to the first inlet (24) of the container (12) and that is configured to supply air into the container (12) as the subject (8) uses the device (4).