A patient interface comprising a cushion having a nasal plenum chamber, an oral plenum chamber, and a passage formed between the nasal and oral plenum chambers. The passage is configured to allow airflow to pass between the nasal and oral plenum chambers. The cushion also includes a valve including valve body and an adjustment structure that is positioned between the nasal chamber and the oral chamber and is movable relative to the valve body. The adjustment structure is movable between an open position that is configured to allow airflow between the nasal plenum chamber and the oral plenum chamber, and a closed position configured to limit airflow between the nasal plenum chamber and the oral plenum chamber. The adjustment structure is configured to allow airflow through a nasal vent in the closed position and is configured to limit airflow through the nasal vent in the open position.

A portable medical ventilator using pulse flow from an oxygen concentrator to gain higher oxygen concentration includes a positive pressure source to deliver pressurized air to the patient and a negative pressure source to trigger the oxygen concentrator. A patient circuit attached to a patient interface mask connects the ventilator to the patient. The ventilator includes a controller module that is configured to generate a signal to the negative pressure device to trigger the concentrator to initiate one or more pulses of oxygen from the oxygen concentrator. The oxygen pulses are delivered to the patient interface directly through multi-tube or a multi lumen patient circuit. The oxygen does not mix with air in the ventilator or in the patient circuit and bypasses the leaks in the patient circuit and/or patient interface.

The invention disclosed herein concerns screening and early detection of a variety of disease conditions in seemingly healthy subjects, enabling early intervention and treatment.

A ventilation system that includes a pressure source, a pneumatic path configured to receive gas from the pressure source and comprising a first pneumatic component coupled to a second pneumatic component. The first pneumatic component includes a first electrical conductor including a first electrical component having a first electrical characteristic. The second pneumatic component comprises a second electrical conductor including a second electrical component having a second electrical characteristic. The first electrical conductor is electrically connected with the second electrical conductor in an electric path. The system performs operations including determining a continuity of the electrical path; displaying a notification regarding the continuity of the electrical path; detecting the unique electrical characteristic of the electric path; and determining a pneumatic characteristic of the pneumatic path.

There is a ventilator for mechanical ventilation during a breathing cycle including an inhalation cycle and an exhalation cycle. The ventilator is configurable to be in fluid communication with a supply of a first fluid. The ventilator includes an inhalation pathway and an exhalation pathway. A first fluid injector is in fluid communication with the supply of the first fluid for injecting the first fluid. The inhalation pathway receives the first fluid injected by the first fluid injector. A controller is operatively connected with the first fluid injector and programmed to selectively actuate the first fluid injector to inject the first fluid, which is received within the inhalation pathway such that an inhalation pressure in the inhalation pathway is within a predetermined range during the inhalation cycle.

A ventilator system for a patient includes: an intubation tube configured to flow oxygen-enriched humidified air (OHA) toward patient lungs and to evacuate exhaust air exhaled from the lungs, the intubation tube includes: a distal end, configured to be inserted into patient trachea, and a proximal end, configured to be connected to tubes for receiving the OHA and evacuating the exhaust air; a first microgravity sensor, coupled to the intubation tube at a first position, and configured to produce a first signal indicative of a first micro-acceleration of the intubation tube at the first position; a second microgravity sensor, coupled to the intubation tube at a second different position, and configured to produce a second signal indicative of a second micro-acceleration of the intubation tube at the second position; and a processor, configured to control the ventilation system to apply a ventilation scheme responsively to the first and second signals.

A processor obtains input of a logistically attainable end tidal partial pressure of gas X (PetX[i].sup.T) for one or more respective breaths [i] and input of a prospective computation of an amount of gas X required to be inspired by the subject in an inspired gas to target the PetX[i].sup.T for a respective breath [i] using inputs required to utilize a mass balance relationship, wherein one or more values required to control the amount of gas X in a volume of gas delivered to the subject is output from an expression of the mass balance relationship. The mass balance relationship is expressed in a form which takes into account (prospectively), for a respective breath [i], the amount of gas X in the capillaries surrounding the alveoli and the amount of gas X in the alveoli, optionally based on a model of the lung which accounts for those sub-volumes of gas in the lung which substantially affect the alveolar gas X concentration affecting mass transfer.

A portable medical ventilator using pulse flow from an oxygen concentrator to gain higher oxygen concentration includes a positive pressure source to deliver pressurized air to the patient and a negative pressure source to trigger the oxygen concentrator. A patient circuit attached to a patient interface mask connects the ventilator to the patient. The ventilator includes a controller module that is configured to generate a signal to the negative pressure device to trigger the concentrator to initiate one or more pulses of oxygen from the oxygen concentrator. The oxygen pulses are delivered to the patient interface directly through multi-tube or a multi lumen patient circuit. The oxygen does not mix with air in the ventilator or in the patient circuit and bypasses the leaks in the patient circuit and/or patient interface.

A conduit for a breathing circuit includes a heater associated, at least in part, with a hydrophilic layer. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic layer. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.

A control system for a heated conduit in a respiratory apparatus includes a power supply configured to provide power to the heated conduit and a heating control circuit configured to control an amount of heat generated in the heated conduit. The control system further includes a sensing circuit configured to indicate the temperature of a sensor positioned in the heated conduit by comparing a reference voltage with a sum of a voltage drop through the sensor and a voltage provided to the sensor by the power supply when the heating control circuit is on. When the heating control circuit is off, the voltage drop through the sensor is solely due to current provided by a current source.