A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, which can include information relating to a potential respiratory equilibrium, and a duration of safe apnoea is determined from the obtained information.

A method of determining a duration of safe apnoea. Information is obtained relating to a respiratory indicator, which can include information relating to a potential respiratory equilibrium, and a duration of safe apnoea is determined from the obtained information.

Systems and methods for hypoxia delivery are provided. An apparatus for providing intermittent normoxia and hypoxia intervals includes a breathing component, a normoxia fluid source, a hypoxia fluid source, a valve, and a control system. The valve is configured to disrupt flow from at least one of the normoxia fluid source and the hypoxia fluid source and the control system is configured to cause the at least one valve to switch between delivery of fluid from the normoxia fluid source and the hypoxia fluid source while maintaining positive pressure at the breathing component.

A respiratory device can include an oxygen generator and a ventilator. The oxygen generator can include a first inlet to ambient air, a vacuum or pressure swing oxygen generating system in fluid communication with the first inlet, a first fluid pathway, and a first outlet. The ventilator can include a second inlet to ambient air and a blower in fluid communication with the second inlet to draw ambient air. The ventilator can include a third inlet in fluid communication with the first fluid pathway upstream of the first outlet. The blower can also be in fluid communication with the second inlet to draw at least some of the extracted oxygen. The ventilator can also include a second outlet in fluid communication with the blower to dispense a mixture of the ambient air and the extracted oxygen to the user.

A respiratory device can include an oxygen generator and a ventilator. The oxygen generator can include a first inlet to ambient air, a vacuum or pressure swing oxygen generating system in fluid communication with the first inlet, a first fluid pathway, and a first outlet. The ventilator can include a second inlet to ambient air and a blower in fluid communication with the second inlet to draw ambient air. The ventilator can include a third inlet in fluid communication with the first fluid pathway upstream of the first outlet. The blower can also be in fluid communication with the second inlet to draw at least some of the extracted oxygen. The ventilator can also include a second outlet in fluid communication with the blower to dispense a mixture of the ambient air and the extracted oxygen to the user.

The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

A method of treating a human subject which is effected by inhalation of gaseous nitric oxide, the method comprising a first treatment period comprising administering gNO by inhalation over a period of about at least 5 days, wherein the first treatment period is followed by a second treatment period comprising administering gNO by inhalation over a period of at least 3 months. The method can be utilized for treating a human subject suffering from, or prone to suffer from, a disease or disorder that is manifested in the respiratory tract, or from a disease or disorder that can be treated via the respiratory tract.

A method for preventing or treating an arrhythmia including administering an effective amount of hydrogen to a patient in need thereof.