Dispensing systems for a ventilator circuit having a ventilator flow circuit with a normal inhalation flow path with a heat and moisture exchanger (HME), a flow sensor in communication with the ventilator circuit, an automated drug dispensing system with an actuator and a pressurized canister residing upstream of the HME, a bypass inhalation flow path residing downstream of the pressurized canister, and at least one electromechanical valve residing in the inhalation flow path to selectively open the valve which can be normally closed to define a closed bypass path. At least one controller opens the at least one electromechanical valve to open the bypass inhalation flow path and close the normal inhalation flow path through the HME only when the flow sensor indicates air flow is in an inhalation direction. Once the valve is open, the actuator dispenses medication through the bypass inhalation flow path to the patient.

Dispensing systems for a ventilator circuit having a ventilator flow circuit with a normal inhalation flow path with a heat and moisture exchanger (HME), a flow sensor in communication with the ventilator circuit, an automated drug dispensing system with an actuator and a pressurized canister residing upstream of the HME, a bypass inhalation flow path residing downstream of the pressurized canister, and at least one electromechanical valve residing in the inhalation flow path to selectively open the valve which can be normally closed to define a closed bypass path. At least one controller opens the at least one electromechanical valve to open the bypass inhalation flow path and close the normal inhalation flow path through the HME only when the flow sensor indicates air flow is in an inhalation direction. Once the valve is open, the actuator dispenses medication through the bypass inhalation flow path to the patient.

A dispenser device for fluid or powder, including an air expeller (20) and a reservoir (30). The reservoir (30) has an air inlet (31) connected to the air expeller (20) and a composition outlet (32) connected to a dispenser opening (10), and is removably mounted on the air expeller. After actuation, the empty reservoir can be removed from the air expeller and replaced with a new reservoir. The air inlet (31) is closed by a first closure element (40) and the composition outlet (32) is closed by a second closure element (50). A mechanical opening system (61, 62) co-operates with the first and second closure elements to expel each closure element from the closed position. The mechanical opening system has a first rod (61) secured to the air expeller (20), and a second rod (62) secured to the dispenser head (1), co-operating with a closure element during actuation.

A dispenser device for fluid or powder, including an air expeller (20) and a reservoir (30). The reservoir (30) has an air inlet (31) connected to the air expeller (20) and a composition outlet (32) connected to a dispenser opening (10), and is removably mounted on the air expeller. After actuation, the empty reservoir can be removed from the air expeller and replaced with a new reservoir. The air inlet (31) is closed by a first closure element (40) and the composition outlet (32) is closed by a second closure element (50). A mechanical opening system (61, 62) co-operates with the first and second closure elements to expel each closure element from the closed position. The mechanical opening system has a first rod (61) secured to the air expeller (20), and a second rod (62) secured to the dispenser head (1), co-operating with a closure element during actuation.

Containment units, dry powder inhalers, delivery systems, and methods for the same are disclosed. Exemplary devices are configured to have inlets and outlets which are formed with the containment walls of a containment unit. Air jets formed by the configuration of inlet(s) and outlet(s) inside the containment unit create significant turbulence and deaggregate the powder. Delivery system components downstream of the containment unit may integrate the exiting aerosol plume with a low flow nasal cannula air stream for delivery to a subject.

Aspects of the invention include devices, systems, and methods for enhancing a user's sleep. A flexible frame supports a flow manifold which can be used in unison with adjoined or adjacently integrated supportive members utilized to create soft objects of various designs and materials. These types of objects can be in the form of a pillow, mattress topper, even a child's stuff animal and other various stationary and portable soft sided padded embodiments as disclosed in this application. These various designs and embodiments house an integrated flow delivery system which is delivers concentrated, pressurized, and or altered gaseous flowing elements in a controlled and fluidic manner as to help address certain types of sleeping and breathing issues during their resting and sleep states.

A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

Devices, systems, and methods are disclosed which permit ventilation therapy concurrent with humidity and aerosol drug delivery. Exemplary mixer-heaters employ alternating actuation of humidity and drug nebulizers and may use a single constant power setting for the heating section while keeping a controlled outlet temperature over the course of treatment.

Devices, systems, and methods are disclosed which permit ventilation therapy concurrent with humidity and aerosol drug delivery. Exemplary mixer-heaters employ alternating actuation of humidity and drug nebulizers and may use a single constant power setting for the heating section while keeping a controlled outlet temperature over the course of treatment.