A nebulizer for producing an inhalable mist of droplets, comprising at least an aerosol generator, a housing having a liquid reservoir and control electronics, the aerosol generator consisting at least of a membrane, a piezo element and a substrate plate, and the control electronics comprising at least an RF generator, a controller, memory and switching elements, and an inductor. The aerosol generator forms a resonant circuit together with the inductor and the control electronics are configured to at least partly excite the aerosol generator to vibrate. The aerosol generator is configured such that aerosol droplets are producible by vibrations and the RF generator is configured to vary the amount of aerosol produced.

A reusable, elastomeric respirator and ventilator, with filter inserts, including a mask body having a pliant facial interface on the interior of the mask body, and two apertures centrally positioned on the front face of the mask body. Two interchangeable plugs or ports are provided to be received within and seal the apertures, deliver oxygen into the mask, or deliver liquids to a wearer of the mask. On opposing sides of the mask body are air filter housings which support an air filter, each air filter housing including a base support structure affixed to the mask body and a top securing structure removably secured to the base support structure. One or more straps are affixed to the mask body to secure the mask body about a wearer's head.

The present invention provides a particulate delivery device with an automatic activation mechanism that pierces or cuts a composition capsule when a cap is removed. The cap cannot be replaced once the device is activated for use. The device allows for gas flow through the device from a gas inlet to a gas outlet through a composition receptacle and dispersion chamber to deliver particulate to the airway of a subject.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

An adaptor for a respiratory assistance system delivers aerosols to a patient. The adaptor is lightweight with a small footprint to increase patient comfort. The adaptor has a nozzle and a sealing mechanism to maintain pressure therein regardless of whether the nozzle is inserted into the adaptor. The adaptor is configured to connect to medical tubing and a medicament delivery device.

Systems, methods, and devices for humidifying a breathing gas are presented. The system includes a source of pressurized breathing gas, a vapor transfer unit external to the source of pressurized breathing gas, a first gas tube connecting the source of pressurized breathing gas to the gas inlet of the vapor transfer unit and having a first length, a liquid supply having a heater that heats liquid, a first liquid tube coupling the liquid supply to the liquid inlet of the vapor transfer unit, and a second gas tube having a second length and connecting the gas outlet to a patient interface. The first length is greater than the second length. The vapor transfer unit includes a gas passage, a liquid passage, and a membrane separating the gas passage and the liquid passage. The membrane is positioned to transfer vapor from the liquid passage to the gas passage.

Distinctly keyed male-female couplers are pneumatically connected to medical ventilator by distinct lines carrying pulsatile gas or sensory signals. Ventilator-mounted female coupler has entranceway cavity and larger receiving cavity delimited by catch edge. Male fence-forming longitudinal winglets extend from sealing plate carry terminal end convexities which latch onto catch edge. Winglets move inward due to larger fence circumference than entranceway and seat on catch. Winglets placed in tension due to locking length less than entranceway span, then convert force into sealing compressive force between sealing plate and female tube end. Conjoining male tube bayoneted and sheathed by projecting female tube, resulting in another gas seal. Two compressive seals formed between male distal port and pneumatic line. Extending male key(s) on winglet insertable into matching female slots. Convexities block insertion of non-matching couplers set due to interference by convexities on female on entranceway edges.

A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

A nebulizer system capable of identifying when activation has occurred and aerosol is being produced. The nebulizer system monitors the inhalation and exhalation flow generated by the patient and communicates proper breathing technique for optimal drug delivery. The nebulizer system may monitor air supply to the nebulizer to ensure it is within the working range and is producing, or is capable of producing, acceptable particle size and drug output rate. When a patient, caregiver or other user deposits or inserts medication into the nebulizer, the nebulizer system is able to identify the medication and determine the appropriate delivery methods required to properly administer the medication as well as output this information into a treatment log to ensure the patient is taking the proper medications. The system is able to measure the concentration of the medication and volume of the medication placed within the medication receptacle, e.g., bowl.

Topical applications that provide a nitric oxide therapy to a surface are provided. Systems for providing a topical nitric oxide therapy can comprise a nitrite medium in a first container, the nitrite medium comprising about 3% of a nitrite component by weight. The system comprises an acidic medium in a second container, the acidic medium comprising about 9% by weight of one or more acidic reactants. The nitrite medium and the acidic medium are configured to be combined to form a nitric oxide topical medium producing nitric oxide suitable for topical application and suitable for administering nitric oxide therapy wherein a therapeutically effective amount of the nitric oxide topical medium is applied to a treatment surface suitable for receiving nitric oxide therapy, whereby the application of the therapeutically effective amount is adapted to deliver a dose of nitric oxide at the treatment surface of a patient.