The present disclosure pertains to a system and method for providing mandibular advancement and sleep positional therapy to a user for a sleep session. The system is formed by a mandibular advancement device for treating obstructive sleep disordered breathing (e.g., obstructive sleep apnea and snoring) that includes an electronics module configured to aid in sleep positional training. The present system and method facilitate advancing a lower jaw of the user into a protruding position relative to an upper jaw of the user to increase a size of an airway of the user, determining whether a posture of the user has breached a posture threshold, and, responsive to a breach, prompting the user to change posture such that the posture of the user no longer breaches the posture threshold.

System and methods are disclosed that promote a sleep stage of a user. The systems and methods determine a current sleep stage of a user during a sleep session, with the user using a respiratory therapy system during the sleep session. The systems and methods further predict an undesired sleep stage upcoming for the user during the sleep session based, at least in part, on (i) one or more user parameters, information from one or more previous sleep sessions, or a combination thereof, and (ii) the current sleep stage. The systems and methods adjust one or more control parameters of the respiratory therapy system, of one or more devices in an environment of the user, or of a combination thereof to promote a desired sleep stage of the user, thereby optimizing sleep of the user.

A device that suppresses a pathological synchronous and oscillatory neuron activity, and includes a non-invasive stimulation for stimulation, using stimuli, of neurons in the patient's brain and/or spinal cord, where those neurons are showing pathologically synchronous and oscillatory neuron activity, and the stimuli are designed to suppress are this activity when administered to the patient. Moreover, a measuring unit records measurement signals reflecting the neuron activity of the stimulated neurons and a control and analysis unit controls the stimulation unit to administer stimuli, check the success of stimulation based on the measurement, and, if the stimulation success is not sufficient, insert one or more stimulation breaks in the application of the stimuli or extend one or more stimulation breaks, where no stimuli that could suppress the pathological synchronous and oscillatory neuron activity are applied during the stimulation breaks.

A multi-function therapeutic system comprising a housing having a top portion having a first radiation therapy unit mounted therein for generating and applying light energy to a person, a bottom portion including a hydrogen therapy unit for supplying hydrogen to the person, and an intermediate bed portion disposed between the top portion and bottom portion. The intermediate bed portion includes an electromagnetic therapy unit for generating and applying electromagnetic energy to the person. The system can also include a vibration therapy unit associated with one or more of the bottom portion and the intermediate bed portion for generating and applying vibrational energy to the person, and a control unit for controlling the first radiation therapy unit, the hydrogen therapy unit, the electromagnetic therapy unit, and the sound therapy unit.

Provided are systems, methods, and devices for biomarker shaping and sleep profile enhancement. Systems include a plurality of electrodes configured to be coupled to a brain of a user and configured to obtain a plurality of measurements from the brain of the user, and an interface configured to obtain the plurality of measurements from at least the plurality of electrodes. Systems also include a processing device comprising one or more processors configured to generate a first target sleep profile for the user based, at least in part, on the plurality of measurements and a plurality of biomarkers, the processing device being further configured to generate a plurality of stimulus parameters based, at least in part, on the target profile.

Provided are systems, methods, and devices for implementation of custom sleep parameters. Methods include receiving, via a user interface, a plurality of input parameters associated with a sleep profile of a user, the plurality of input parameters representing at least one sleep profile target, generating, using one or more processors of a processing device, a plurality of sleep parameters based, at least in part, on the received plurality of input parameters, the plurality of sleep parameters representing one or more changes to one or more biomarkers of the user, and generating, using one or more processors of the processing device, a plurality of stimulation parameters based, at least in part, on the plurality of sleep parameters, the plurality of stimulation parameters representing stimuli configured to implement the identified changes for each of the identified biomarkers of the user's sleep profile.

The system receives a raw signal carrying information related to slow wave activity; buffers a portion of the raw signal; determines a timing of slow wave events in the buffered portion of the raw signal; filters the raw signal; determines a timing of slow wave events in the filtered raw signal; compares the timing of the slow wave events in the buffered portion of the raw signal to the timing of the slow wave events in the filtered raw signal; determines a first correction factor associated with reducing slow wave activity in the subject and a second correction factor associated with enhancing slow wave activity in the subject; and adjusts a timing of the stimulation provided to the subject during the sleep session based on the first and/or second correction factors.

A stimulation application apparatus includes a substrate, a stimulation application member provided on one surface of the substrate to apply a stimulation to a site, and a stimulation imposition layer provided on another surface of the substrate opposed to the first surface to impose the stimulation. The site includes at least one area selected from a group of (F) site that intersects the perpendicular line of the medial malleolus on an extension line of the medial margin on os metatarsale primam 1 and 2 in foot sole, and (L) incisurasive foramen supraorbitalis site, and (K) site where the lintersection of the line connecting an augulus oculi medialis of eye and L site, and perpendicular of an augulus oculi lateralis of eye is located, and (M) site of augulus oculi lateralis located above 1 horizontal finger from center of the line where connect the inner end of left and right eyebrow.

The present invention presents methods and apparatus for detecting, imaging, monitoring, and modulating of brain activities and neuronal activities in the brain using radiofrequency (RF) electromagnetic (EM) waves, as well as methods and apparatus for detecting, imaging, and monitoring breathing and heart-beating using RF EM waves.

An apparatus for use in treating a neurological disorder of the auditory system, including a sound processing unit, an audio stimulation unit and a somatosensory stimulation unit. The audio stimulation unit includes an input for receiving the modified audio signal from the sound processing unit. The sound processing unit includes a processor operable to analyze an audio signal and generate a modified audio signal and a plurality of actuation signals therefrom representative of the audio signal. The somatosensory stimulation unit includes an array of stimulators to apply a somatosensory stimulation to a subject, and an input for receiving the plurality of actuation signals from the sound processing unit and directing individual actuation signals in a predetermined output for delivering an audio stimulation to the subject.