Disclosed is an endoscope for measuring intra-organ pressure (e.g., intragastric pressure), and more particularly an endoscope for measuring intra-organ pressure (e.g., intragastric pressure) and visualizing the response of an adjacent sphincter (e.g., lower esophageal sphincter) to changes in the intra-organ pressure.

An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.

An occlusion catheter system includes a proximal hub having an inflation connection port and an inflation pathway. An inflation catheter member is connected to the proximal hub and has an inflation lumen. A stiffener member defines a longitudinal axis. The proximal end of the stiffener member is connected to the proximal hub. The stiffener member extends through a portion of the inflation lumen. An occlusion balloon has a proximal balloon end and a distal balloon end. A distal catheter member is positioned substantially on the longitudinal axis and is connected to the distal end of the stiffener member. An atraumatic tip is positioned on a distal end of the distal catheter member. The atraumatic tip has a substantially circular profile in a relaxed configuration. A pressure sensor is connected to the occlusion catheter system distally relative to the occlusion balloon and is connected to a processor by electrical wiring.

A catheter insertable into a patient for monitoring pressure having an expandable outer balloon. An expandable inner balloon is positioned within the lumen of the catheter and has having a second outer wall and forms a gas chamber to monitor pressure within the patient. In response to pressure exerted on the outer wall of the outer balloon, fluid within the outer balloon enters an opening in the wall of the catheter lumen to exert a pressure on the outer wall of the expanded inner balloon to deform the inner balloon and compress the gas within the inner balloon. A pressure sensor communicates with the gas containing chamber for measuring pressure based on compression of gas caused by deformation of the expanded inner balloon resulting from deformation of the expanded outer balloon.

An implantable ureteral stent for implanting in the ureter comprising a first end for placing in the renal pelvis and a second end for placing in the bladder, each said end including a pressure sensor arranged to measure urinary pressure. Each pressure sensor can include an electronic circuit with electronic components and a substrate for receiving the electronic circuit and electronic components, wherein said substrate is a flexible membrane. The flexible membrane can be a sleeve surrounding the stent or the flexible membrane can be a flexible tube that is part of a thin tube that forms the stent, in particular the flexible membrane may have a thickness of 80-150 μm. The electronic components can be connected by wire-bonding. Each pressure sensor can have a flexible PCB having soldered electronic components. A manufacturing method is disclosed to make said implantable ureteral stent.

A strain gauge (10, 40, 50), a pressure sensor (20, 60), and an interventional medical catheter. The strain gauge (10, 40, 50) comprises a substrate (11) and at least two sensitive gages (1, 2) provided on the substrate (11), the at least two sensitive gages (1, 2) being arranged along two mutually perpendicular directions and sharing one ground port (3). The pressure sensor (20, 60) comprises an elastic body (21, 61) and the strain gauge (10, 40, 50) provided on the elastic body (21, 61). The interventional medical catheter comprises a catheter distal end and the pressure sensor (20, 60) provided at the catheter distal end. The present application not only saves the trace space for mounting and using the strain gauge (10, 40, 50) on the interventional medical catheter, facilitating the successful mounting and use of the strain gauge (10, 40, 50) on the interventional medical catheter, improving the adaptability of the strain gauge (10, 40, 50), but also reduces the size of the strain gauge (10, 40, 50), thereby shortening the length of the elastic body (21, 61) of the pressure sensor (20, 60) and reducing the size of the interventional medical catheter.

A device can detect and retrieve a blood clot by advancing a catheter with a clot sensing element through a patient’s vascular system. The catheter can map, using an electromagnetic sensor disposed at a distal end of the clot sensing element, the patient’s vascular system. A force sensor can generate a position signal indicating the clot sensing element contacted the clot in the patient’s vascular system. Once located, a blood clot retrieval device can be deployed through the catheter and a lumen in the clot sensing element to remove the clot from the patient’s vascular system.

A system and method for evaluating blood flow in a vessel of a patient includes a catheter containing a first pressure sensor and a second pressure sensor and configured to simultaneously measure pressure data within a vessel on either side of a stenosis. Pressure data generated by the catheter includes a first series of pressure measurements from the first pressure sensor a second series of pressure measurements from the second pressure sensor. The system and method further includes a fractional flow reserve (FFR) calculation module executable on one or more processors and configured to calculate a stability index for each of two or more portions of the pressure data, wherein each stability index indicates at least one of heart rate stability and catheter stability for the respective portion of the pressure data. An optimal time window is identified based on the stability indexes for calculation of FFR based on the pressure data. A FFR value is then calculated based on the pressure data in the optimal time window.

Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a temperature of the bodily fluid flowing therethrough.

An occlusion catheter system includes an inflation catheter member and an occlusion balloon. The proximal and distal balloon ends are connected to the inflation catheter between the proximal and distal catheter ends. A distal pressure sensor is attached to the inflation catheter member between the proximal balloon end and the atraumatic tip. An inflatable spine is connected to the inflation catheter. The proximal spine end is connected to the inflation catheter near the proximal balloon end and the distal spine end is connected to the inflation catheter near the distal balloon end. The occlusion balloon and the inflatable spine are configured to define blood flow channels with the internal surface and the external balloon surface when the occlusion catheter system is at least partially positioned in the vessel and the occlusion balloon and the inflatable spine are in a partially inflated configuration.