Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

A pressure-measuring system, including a tube system having at least first and second pressure measuring devices, each including a pressure transducer membrane and a measuring chamber. A first flow regulation device with a perfusion tube section is positioned between the first pressure measuring device and a supply of fluid, and has a first tube clamp that acts on a tube section by squeezing. The system further includes at least one non-perfusion regulation device.

Cannula for fluid perfusion comprising a tubular body extending from a proximal portion to a distal portion thereof, the tubular body being provided with an internal cavity defining a first opening in the distal portion allowing a fluid to exit the cavity in a first direction, the tubular body comprising a connection portion lying between the proximal and distal portions, the connection portion being designed to be inserted into a blood vessel by the distal portion. The cannula furthermore comprises a duct extending from a first end to a second end thereof, the second end being provided with an auxiliary opening placed at the connection portion so as to allow a fluid to exit the duct in a second direction opposite to the first direction. The first end is placed in fluid communication with the cavity so that a fluid flowing in the cavity toward the first opening flows at least in part into the duct, said duct being provided with a valve device designed to shut off, or allow, the flow of a fluid flowing through the duct from one end to the other thereof, depending on whether the valve device is in a first configuration or a second configuration, respectively.

A catheter and guide wire assembly (10) for measurement of blood pressure in a living body, comprising: a proximal tube (11) having a distal end and a proximal end; a distal tube (12) having a distal end and a proximal end, which is connected to the distal end of the proximal tube (11); a fluid-permeable coil (13) having a distal end and a proximal end, which is connected to the distal end of the distal tube (12); a distal tip (14), in which the distal end of the fluid-permeable coil (13) is secured; and a core wire (16), which is attached in the proximal tube (11) and which extends through a portion of the proximal tube (11), the distal tube (12) and the fluid-permeable coil (13), and is secured in the distal tip (14), wherein the distal end of the proximal tube (11) and the proximal end of the distal tube (12) are connected by a butt joint and wherein the core wire (16) is glued or brazed to the inner wall of the proximal tube (11) at or close to the butt joint.

Medical device systems and methods for making and using medical device systems are disclosed. An example medical device system includes a control system having a processor and a pump, a first expandable member coupled to the processor and configured to be positioned in the superior vena cava. The system also includes a second expandable member coupled to the processor and configured to be positioned in the inferior vena cava. The system also includes a first sensing member designed to sense a first parameter. The system also includes a second sensing member designed to sense a second parameter. Additionally, the pump is designed to expand or contract the first expandable member, the second expandable member or both the first and the second expandable members based on a change in the first parameter, the second parameter or a change in both the first and the second parameters.

The present disclosure relates to an intravascular catheter with sensor systems that can measure intravascular pressure using MEMS sensors. Devices of the present disclosure can also be used to administer intravenous therapies, such as drug delivery or hemodialysis. Exemplary devices can be equipped with multiple MEMS sensors to measure pressure in multiple locations throughout the cardiovascular system. The intravascular catheter can communicate with a receiver and monitor to display sensor data.

Foley type catheter embodiments for sensing physiologic data from a urinary tract of a patient are disclosed. The system includes the catheter and a data processing apparatus and methods for sensing physiologic data from the urinary tract. Embodiments may also include a pressure sensor having a pressure interface at a distal end of the catheter, a pressure transducer at a proximal end, and a fluid column disposed between the pressure interface and transducer. When the distal end is residing in the bladder, the pressure transducer can transduce pressure impinging on it into a chronological pressure profile, which can be processed by the data processing apparatus into one or more distinct physiologic pressure profiles, for example, peritoneal pressure, respiratory rate, and cardiac rate. At a sufficiently high data-sampling rate, these physiologic data may further include relative pulmonary tidal volume, cardiac output, relative cardiac output, and absolute cardiac stroke volume.

A pressure sensor configured for biological pressure measurement at a distal end portion of an elongated member comprises a dissolvable hydrophilic material coated on a surface of the pressure sensor. A guide wire for biological pressure measurement may include a tube extending along a longitudinal axis of the guide wire; and a pressure sensor for biological pressure measurement, at least a portion of the pressure sensor being mounted within the tube. The pressure sensor comprises a pressure sensor membrane facing a top side of the tube. A circumferential wall of the tube includes at least six openings: a first distal opening, a second distal opening located on a right side of the tube, a third distal opening located on a left side of the tube, a first proximal opening, a second proximal opening located on a right side of the tube, and a third proximal opening located on a left side of the tube. The first distal opening is larger than the second and third distal openings, and the first proximal opening is larger than the second and third proximal openings.

Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

A multi-lumen catheter for monitoring intra-abdominal pressure, the catheter including an expandable outer balloon and an expandable inner balloon positioned within the outer balloon. A first lumen communicates with the inner balloon and the inner balloon and first lumen are filled with gas to form a gas filled chamber to monitor pressure within the bladder to thereby monitor pressure within an abdomen of the patient. A second lumen communicates with the bladder to remove fluid from the bladder. The catheter is configured for attachment of an external pressure transducer communicating with the gas filled chamber for measuring bladder pressure based on gas compression caused by deformation of the expanded inner balloon deformed by the expanded outer balloon.