A catheter system may include a catheter adapter, which may include a distal end and a proximal end. The catheter system may include a catheter, which may include a distal end, a proximal end, a catheter lumen extending through the distal end of the catheter and the proximal end of the catheter, and an inner surface forming the catheter lumen. The catheter may extend distally from the distal end of the catheter adapter. The distal end of the catheter may include one or more holes. The distal end of the catheter may include one or more channels. The holes and/or the channels may facilitate visualization of blood flashback indicating the catheter is disposed within a vein of a patient.

A balloon catheter has an outer shaft which surrounds a shaft lumen. The outer shaft has a proximal outer shaft portion connected to a distal outer shaft portion. An inner shaft is in a distal portion of the shaft lumen. A guide wire lumen is in the inner shaft. An opening at a proximal end portion of the inner shaft permits the guide wire to be guided out from the outer shaft. A metallic tube is in the shaft lumen. The proximal end portion of the inner shaft is engaged with the metallic tube. A separate, elongate and metallic stiffening element is in the shaft lumen, and is connected to the metallic tube and protrudes from the metallic tube into the distal portion of the shaft lumen and into the proximal portion of the shaft lumen to stiffen portions of the outer shaft.

An intravascular heart pump assembly can include a rotor with at least one impeller blade, and a cannula. The present application describes various cannulas that can be manufactured from multiple layers of material to improve flexibility, manufacturability, and durability without increasing an outer diameter of the cannula. In one embodiment, the cannula includes an inflow section having a sheet formed of a shape memory material embedded within a polymer and having at least one lateral hole or aperture in the inflow section. The at least one lateral hole is defined by a first hole in the sheet and a second hole in the outer polymer layer of the cannula. The first hole and the second hole overlap so that blood can enter the cannula through the holes.

An invasive medical device (10) is disclosed comprising a flexible sheath (11) enveloping at least one lumen (17, 17′) comprising an electrically conductive wire (20) including a deformable actuator (21) for deforming a section of the invasive medical device in response to an electric current provided through the electrically conductive wire, wherein the flexible sheath comprises a set of apertures (31) extending through the flexible sheath to the at least one lumen, said apertures being filled with an adhesive (33) anchoring the deformable actuator to the flexible sheath. A manufacturing method for such an invasive medical device (10) is also disclosed.

An infusion catheter system may deliver a therapeutic agent to a desired location in the body. The system may include an elongate catheter shaft having a proximal end region, a distal end region, a distal opening, and a lumen extending between the proximal end region and distal opening. The distal end region may include a coiled portion having a preformed coiled configuration including a plurality of helically wound rings. A plurality of apertures may be formed through a sidewall of the coiled portion. A guidewire may be configured to be slidably disposed within the lumen of the catheter shaft. The guidewire may include a proximal end region having a first cross-sectional dimension, an enlarged distal end region having a second cross sectional dimension greater than the first cross-sectional dimension, and an intermediate region disposed between the proximal end region and the distal end region.

Provided herein are dual-lumen catheters, systems, and methods thereof. In some embodiments, for example, a catheter assembly configured for modifying intravascular lesions is provided including a core wire, a dual-lumen extrusion including the core wire, and a manifold disposed around a portion of the dual-lumen extrusion. The core wire includes a proximal end configured to vibrationally couple to an ultrasound transducer. The dual-lumen extrusion includes a first lumen and a second lumen. The core wire is disposed within the first lumen, and the second lumen is configured to accommodate a guidewire. The manifold is disposed around at least a skived proximal-end portion of the dual-lumen extrusion, wherein the skived portion includes the second lumen without the first lumen. In some embodiments, the catheter assembly further includes the ultrasound transducer. In some embodiments, a system console includes the ultrasound transducer.

A bi-directional valve assembly, including valves for use in closed-ended catheters or other elongate tubular devices, is disclosed. In one embodiment, a catheter assembly for insertion into a body of a patient is disclosed and comprises an elongate catheter tube including an outer wall that at least partially defines at least one lumen that extends between a proximal end and a closed distal end thereof. The catheter tube includes a valve assembly that in turn includes a linear slit valve defined through the outer wall of a distal segment of the catheter tube, and a deformation region. The deformation region includes a compliant segment disposed in the outer wall of the catheter tube and a thinned portion of the outer wall. The compliant segment and thinned portion of the deformation region cooperate to preferentially deform the outer wall and open the slit valve during aspiration through the catheter tube.

A catheter or shaft, such as a distal access support or aspiration catheter, is provided that is configured to be advanced at least partially within a patient. The catheter or shaft may include a flexible and hollow shaft including a proximal end and a distal end. The flexible and hollow shaft may include a slotted portion with a plurality of slotted openings, the slotted portion including a first segment with a first pattern of slotted openings and a second segment extending proximally relative the first segment with a second pattern of slotted openings different from the first pattern.

A peripheral catheter having a catheter tip diffuser for reducing an exit velocity of an infusant within the catheter. Pluralities of diffusion side holes are provided on the tip portion of the catheter. Some examples further include pluralities of annularly arranged, staggered diffusion holes provided on the tip portion of an intravenous catheter to streamline infusant issued from the diffusion holes. An inner surface of each diffusion hole is further angled relative to the inner surface of the catheter lumen such that an infusant within the lumen exits the catheter though the diffusion holes at an angle less than 90°.

A drug delivery device includes a blunt cannula and a reservoir. The blunt cannula has a cylindrical wall that defines an axial passage between a first end and a second end of the blunt cannula. The wall has at least a first tapered region at the first end to define an opening in fluid communication with the axial passage and adapted at the first end to resist interruption of fluid flow through the axial passage and out of the first end of the blunt cannula. The reservoir is connected to the second end of the blunt cannula.