Urinary catheters and methods for preventing bacterial infections.

An antimicrobial solution for a medical device having a chamber defined by a wall, the chamber being configured to be includes water, and an amount of iodine in the water sufficient to generate free elemental iodine when introduced into the chamber of the medical device. The free elemental iodine is configured to diffuse through the wall of the chamber and/or be embedded in the wall of the chamber of the medical device to form an antimicrobial polymer on the wall of the chamber.

The present disclosure relates generally to materials and medical devices impregnated with antimicrobial compounds. More specifically, the materials are medical matrix materials comprising nanopores or nanochannels in which the antimicrobial compounds are disposed. In other embodiments, medical matrix materials comprises nanomaterials and antimicrobials distributed throughout the material. The materials described herein are useful for a broad spectrum of medical devices and consumer products. The present disclosure further provides methods of making the antimicrobial materials and medical devices disclosed herein.

Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.

The disclosure provides a device and method for managing urinary incontinence. The device includes a platform, a balloon, and a valve. The platform and balloon can include a silicone material, a thermoplastic material, and an adhesive and/or a cement for sealing the urethra. The thermoplastic and silicone materials can soften at the body temperature so that their shape can be adapted to fit the three-dimensional contour of surfaces of the urethra. The balloon seals the internal orifice of the urethra, and the platform can block the leakage associated with the balloon. The valve permits selective urine voiding. The method includes inserting the device into the urethra and the bladder. The method can also include inflating the balloon. The method can further include pulling the balloon so that the balloon is in sealing contact with the neck of the bladder and moving the platform to a suitable position for sealing the urethra.

A pressure relief device for use in a percutaneous procedure, the device comprising a tube having a distal opening into an internal lumen and a proximal opening from the internal lumen, a length of the tube sized to position the distal opening near a closed arteriotomy in a vessel and the proximal opening remains external to a patient’s skin. Related devices, kits, and methods are provided.

Urinary tract infections UTI may be over-diagnosed in very young children because of contamination of a urine specimen by external bacteria when using a conventional catheter. The subject matter disclosed herein relates to a coaxial catheter system and methods for its use, comprising an outer catheter that shields the distal collection opening of an inner catheter during insertion of the system through the meatus. Once the system has been deployed, the distal opening of the inner catheter is exposed in order to collect uncontaminated urine. The system may include a variety of mechanisms to advance the inner catheter relative to the outer, or to retract the outer catheter relative to the inner, a halting mechanism to limit distal movement of the outer catheter, a stopping mechanism to limit distal movement of the inner catheter, and a stabilization mechanism to hold the deployed system in place in male patients.

An intermittent catheter, preferably a female intermittent catheter, is provided in an assembly. The assembly may include a cap which may be attachable to the base of the assembly in use, and/or a seal which misaligns with sealing surfaces of a chamber wall and a moveable insert in use. It may have a two-step deployment, and/or a sheath that pulls out a storage chamber. Internal and external housing may define the storage chamber. The housing may have a filling aperture and/or the storage chamber may comprise an insert configured to move axially in response to rotation.

An intermittent catheter, preferably a female intermittent catheter, is provided in an assembly. The assembly may include a cap which may be attachable to the base of the assembly in use, and/or a seal which misaligns with sealing surfaces of a chamber wall and a moveable insert in use. It may have a two-step deployment, and/or a sheath that pulls out a storage chamber. Internal and external housing may define the storage chamber. The housing may have a filling aperture and/or the storage chamber may comprise an insert configured to move axially in response to rotation.

An intermittent catheter, preferably a female intermittent catheter, is provided in an assembly. The assembly may include a cap which may be attachable to the base of the assembly in use, and/or a seal which misaligns with sealing surfaces of a chamber wall and a moveable insert in use. It may have a two-step deployment, and/or a sheath that pulls out a storage chamber. Internal and external housing may define the storage chamber. The housing may have a filling aperture and/or the storage chamber may comprise an insert configured to move axially in response to rotation.