The present disclosure discloses a nephrostomy tube and a nephrostomy tube with curved drainage. The nephrostomy tube with curved drainage includes a bending head, a balloon element, and an elongated main body integrally connected with each other, wherein the nephrostomy tube with curved drainage has an guiding channel adapted for a guiding member to penetrate through, wherein the bending head has a first inner channel and at least two drainage bending channels located on the outer side of the first inner channel, wherein the balloon element has an air chamber and a second inner channel, wherein the at least two drainage bending channels are communicated with the second inner channel, wherein the elongated main body has a third inner channel communicated with the second inner channel of the balloon element, wherein the first inner channel, the second inner channel and the third inner channel from the guiding channel.

A bi-directional perfusion cannula is provided that includes an elongate tube for insertion into an artery. The elongate tube has a first aperture at a distal end of the tube which is forward during insertion and configured so that blood can flow into the artery in the direction of insertion, an elbow formed in the elongate tube, and a second aperture formed in or slightly rearward of the elbow and configured for supplying blood into the artery in a second direction which is generally opposite to the insertion direction.

Disclosed herein is a multilayered tape comprising a first layer; where the first layer comprises a first surface and second surface; the first surface of the first layer having a surface texture; a second layer; the second layer having a first surface and a second surface; where the first surface of the second layer is closer to the second surface of the first layer than the second surface of the second layer; where the second surface of the second layer contains at least one partition that is parallel to a longitudinal direction of the multilayered tape.

An anti-fouling surface having micron scale pillars embedded with Fe.sub.3O.sub.4 nanoparticles is designed. The pillars may be repeatedly induced to move according to a predetermined frequency, such as one that mimic that of the beating movement of natural cilia, through the application of a magnetic field. When square-shaped pillars with a height of 10 μm, width of 2 μm, and inter-pattern distance of 5 μm actuated for three minutes, more than 99.9 percent of biofilm cells were detached and via gentle rinsing from the surface having the pillars. The anti-fouling surface enables effective prevention of biofilm formation and removal of established biofilms, and can be applied to a broad spectrum of polymers.

Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes inserting an intramural crossing device into the vascular lumen, positioning at least the distal tip of the crossing device in the vascular wall, advancing an orienting device over the crossing device such that an orienting element of the orienting device resides in the vascular wall, inserting a reentry device, and re-entering the true vascular lumen.

A method is described for decreasing activity of at least one sympathetic nerve, nerve fiber or neuron innervating at least one blood vessel in the pulmonary vasculature of a patient to ameliorate pulmonary hypertension. In one embodiment, the method may involve advancing an intravascular treatment device to a target location in a target blood vessel within the pulmonary vasculature of the patient and using the treatment device to decrease activity of at least one sympathetic nerve, nerve fiber or neuron innervating the target blood vessel at or near the target location to ameliorate pulmonary hypertension.

A component for a syringe is disclosed. The component has formed a structure which has a friction-reducing effect due to its shape in the syringe. The component can be, for example, a cylinder, a piston or a seal for the syringe. The structure comprises, for example, elevations or depressions which have a linear, punctiform, elliptical or polygonal design. Also disclosed is a syringe which has at least one such component. The use of a component with a friction-reducing structure makes it unnecessary to use an additional friction-reducing coating, for example silicone, which can lead to undesirable effects on the medicament to be administered with the syringe.

A catheter configured for partial implantation into a patient and drainage of a body cavity may be provided with microtextured surface on one or more inner diameter surfaces and/or outer diameter surfaces of the tubular catheter body. The microtexturing may include surface features dimensioned to inhibit colonization and/or migration of microbes. The microtexturing may also include channels or other recesses containing an antimicrobial agent such as chlorhexidine gluconate or any other effective antimicrobial agent.

The invention comprises an indwelling medical device which is capable of delivering a therapeutic agent evenly along the length of the indwelling portion, including the outer wall, of the device.

The present invention relates to a cover having a plurality of moveable, external, angled projecting elements for use with flexible medical scoping devices such as endoscopes or enteroscopes. The invention includes the cover with an over cuff and use of the disposable removable covering in methods of medical scoping procedures or examinations. The invention also includes an applicator for assisting in placing the covering about or over a medical device and a kit of parts.