One embodiment provides a balloon catheter which has an inner tube having a main lumen and an outer tube which forms an expansion lumen. A part of the inner tube is connected to the outer tube at a position closer to the proximal end than a balloon, a side hole is open at the connection section, and a weak section is provided to the inner tube a position closer to the distal end than the side hole. The weak section has lower rigidity than the remaining portion of the inner tube. When the balloon is expanded by fluid supplied to the expansion lumen, the weak section is pressed by the fluid pressure to thereby close the main lumen of the inner tube.

A balloon catheter that includes an elongated main body extending in an axial direction and a balloon connected to the distal portion of the elongated main body. The balloon includes an interior and is inflatable and deflatable. The balloon catheter also includes a plurality of elongate bodies extending radially away from the outer surface of the balloon. The elongate bodies are crystals of a water-insoluble drug. The elongate bodies each possess an independent longitudinal axis. Each of the elongate bodies includes a base portion at the proximal end of the elongate body. A plurality of elongate body proximal portions extend radially inwardly from the base portion of each of the elongate bodies toward the interior of the balloon. The elongate body proximal portions are continuous extensions of the crystal of the water-insoluble drug.

A balloon catheter, in particular for delivering medicaments, stents or medicament-coated stents in the region of a stenosis, comprising an outer shaft (4) an inner shaft (6), and a balloon (7) at the distal catheter end, which balloon is dilatable by a feedable pressure fluid and which is attached with its proximal end (8) to the outer shaft (4) and with its distal end (9) to the inner shaft (6) which protrudes the outer shaft (4) in the distal direction, and a cover sheath (15) which is seated in a covering position over the contracted balloon (7) and is displaceably guided on the outer shaft (4) and which is displaceable on the outer shaft (4) in the proximal direction via its front opening (17) by the dilating balloon (7) while continuously releasing the same from distal to proximal.

A balloon catheter includes a one-piece extrusion having inner and outer tubular walls, where the inner tubular wall defines a wire guide lumen, and a clearance extending between the inner and outer tubular walls forms an inflation lumen. A balloon is attached to the outer tubular wall and to the inner tubular wall, such that the inflation lumen is in fluid communication with the balloon and the wire guide lumen extends through the balloon. A method of making the balloon catheter is also disclosed.

Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

A balloon catheter is described, having a reinforced, co-axial, duel lumen design. At least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element.

A manipulator, including an elongated chassis containing a U-shaped channel defining a distal direction and a proximal direction. The manipulator also includes an adjuster that is configured to slide in the U-shaped channel. The adjuster includes a first wheel which on rotation translates a guidewire positioned in the adjuster along an axis of the guidewire, and a second wheel which on rotation rotates the guidewire positioned in the adjuster about the axis of the guidewire. The adjuster also includes a port, distal to the first and the second wheel, that is configured to accept a tubular balloon and the guidewire.

A balloon catheter that includes an elongated main body extending in an axial direction and a balloon connected to the distal portion of the elongated main body. The balloon includes an interior and is inflatable and deflatable. The balloon catheter also includes a plurality of elongate bodies extending radially away from the outer surface of the balloon. The elongate bodies are crystals of a water-insoluble drug. The elongate bodies each possess an independent longitudinal axis. Each of the elongate bodies includes a base portion at the proximal end of the elongate body. A plurality of elongate body proximal portions extend radially inwardly from the base portion of each of the elongate bodies toward the interior of the balloon. The elongate body proximal portions are continuous extensions of the crystal of the water-insoluble drug.

A balloon catheter is described having a reinforced, co-axial, duel lumen design. In some embodiments, the balloon catheter includes a purging mechanism designed to purge air from the balloon.

Disclosed herein is a method of producing high purity pentagalloyl glucose (PGG), analogues or derivatives thereof, at least 99.9% pure, by washing with dimethyl ether. PGG may be provided in a kit, including a hydrolyzer for dissolving the PGG and a saline solution. Also disclosed herein is a device for delivery of a therapeutic solution to a blood vessel. The device may be a catheter having an upstream balloon and a downstream balloon. The upstream balloon may be expanded to anchor the catheter and occlude antegrade blood flow. The downstream balloon may be expanded to occlude retrograde blood flow, creating a sealed volume within the blood vessel. The downstream balloon may have pores configured to deliver a therapeutic inflation solution into the sealed volume or a portion thereof. The downstream balloon may be expanded by the expansion of a balloon disposed inside the downstream balloon.