A system has a balloon guide catheter for use in mechanical thrombectomy procedures which requires very little preparation to inflate the balloon compared to most contemporary designs. The balloon guide catheter can have an elongated tubular member and a proximal luer. The elongated tubular member of the catheter can have two internal lumens. A first inner hollow lumen can have a large opening for aspiration and the advancement of auxiliary devices, and a second inflation lumen can provide a fluidic passageway to inflate the balloon. The proximal luer can have a luer lumen, an inflation port, and a mandrel hub. A removable mandrel can extend distally from the mandrel hub to occupy the full length and volume of the inflation lumen of the tubular member. A tab of the mandrel can extend external to the luer to facilitate removal of the mandrel from the catheter prior to inflating the balloon.

A negative pressure therapy system is provided for inducing negative pressure in a portion of a urinary tract of a patient, the system including: (a) at least one ureteral catheter configured to be positioned within a ureter and/or kidney of a patient; (b) one or more sensor(s) configured to determine information about urine produced within a urinary tract of the patient; and (c) a controller configured to increase urine production of the patient by adjusting one or more operating parameters of a negative pressure source for inducing negative pressure through the at least one ureteral catheter into the urinary tract of the patient, based at least in part upon the information determined by the one or more sensor(s).

Intravascular delivery system for deployment of a therapeutic device, such as a stent, in a controlled and robust manner is supported by a lockable balloon catheter equipped with a locking mechanism configured to lock in vivo to a delivery component, such as a guidewire. The lockable balloon catheter can be controllably transitioned between a locked and an unlocked modes of operation by inflation/deflation of the balloon of the lockable balloon catheter. Being in the locked mode of operation, the lockable balloon catheter facilitates delivery of the therapeutic element along the delivery component to a target site while enhancing the stability of the delivery component, especially near the target site.

In some examples, a catheter assembly includes a delivery catheter defining a delivery catheter lumen, a delivery catheter handle connected to the delivery catheter, a retrieval catheter defining a retrieval catheter lumen configured to receive the delivery catheter, and a retrieval catheter handle connected to the retrieval catheter. A proximal end of the retrieval catheter handle is configured to removably couple to a distal end of the delivery catheter handle.

A medical device including a catheter body, a first elongate body, and a service loop ring. The catheter body has a catheter shaft. The first elongate body extends through at least part of the catheter shaft and is configured to move longitudinally in the catheter shaft. The first elongate body is looped through the service loop ring to form a service loop configured to expand and contract as the first elongate body moves longitudinally in the catheter shaft.

A dilation apparatus includes a shaft, a dilation balloon, and a standoff member. The shaft includes a first lumen and a second lumen. The distal end of the second lumen is proximal to the distal end of the first lumen. The dilation balloon encompasses the second distal end of the second lumen such that the dilation balloon defines an interior in fluid communication with the second lumen. A distal portion of the standoff member is positioned within the interior of the dilation balloon. The distal portion of the standoff member is distal to the second distal end of the second lumen. The standoff member provides a pathway for fluid communication between the interior of the dilation balloon and the second lumen. The standoff member may include a tube, a thread, polymeric beading, or other structures.

A ureteral catheter is provided, including a drainage lumen including a proximal portion and a distal portion configured to be positioned in a patient's kidney, renal pelvis, and/or in the ureter adjacent to the renal pelvis, the distal portion including a retention portion for maintaining positioning of the distal portion of the drainage lumen, the retention portion including at least two openings on a sidewall of the retention portion for permitting fluid flow into the drainage lumen wherein a total area of a proximal most opening of the at least two openings is less than a total area of more distal opening(s) nearer to the distal end of the drainage lumen, and wherein when negative pressure is applied through the ureteral catheter, fluid is drawn into the ureteral catheter through the at least two openings.

A method of making a medical device includes holding a spacer tool by a slot of a mold, and accommodating a portion of a first tube by a lumen in the spacer tool, wherein a region of the first tube is inside the mold cavity and outside the spacer tool, and an end of the first tube is in engagement with an end of a first lumen-defining section of a first core pin. The spacer tool includes a first section located in the mold cavity when the spacer tool is held by the slot of the mold, the first section of the spacer tool being configured to define a cavity to be formed circumferentially around a part of the first tube inside a hub to be formed, wherein the part of the first tube is different from the region of the first tube.

A right ventricle-pulmonary artery conduit provides a first end having a first disc extending radially therefrom and a second disc, proximate to the first disc. The second disc extends radially from the first end. An expandable lumen section extends between the first disc and the second disc. The conduit also has a second end, distal from the first end.

A mold system for making a medical device includes a mold having a mold cavity for receiving a material; first and second core pins, each having a first lumen-defining section located, or otherwise configured for placement, in the mold cavity; and a spacer tool having a lumen sized for accommodating a first tube that is in a fixed position with respect to the mold, wherein a first end of the first tube is engaged with the first lumen-defining section of the first core pin, and wherein the spacer tool comprises a first section configured for placement in the mold cavity of the mold, the first section of the spacer tool having a first outer cross-sectional dimension that is larger than an outer cross-sectional dimension of the first tube.