Systems and methods for implanting an endovascular shunt in a patient is disclosed. The system having an expandable anchor configured for being deployed in a dural venous sinus of a patient at a location distal to a curved portion of a wall of an inferior petrosal sinus (IPS) of the patient; an elongate guide member coupled to, and extending proximally from, the anchor; a shunt delivery catheter having a first lumen configured to receive the guide member, and a second lumen extending between respective proximal and distal openings in the shunt delivery catheter, the shunt delivery catheter further having a penetrating element coupled to a distal end of the catheter; and the system further having a guard at least partially disposed over, and movable relative to, the penetrating element.

A drainage or infusion catheter and methods of use are disclosed. In one embodiment, the catheter includes a tube body having a proximal end and a distal end, and a plurality of ports arranged along the tube body from the distal end to the proximal end. The distal end of the tube body is configured to deform around itself into a substantially spiral shape so as to cover at least one of the plurality of ports located near the proximal end of the tube body. In another embodiment, a flap is configured to erupt from apertures arranged in the tube and extend outwardly around the tube body so as to cover at least one of the plurality of ports located near the proximal end of the tube body.

A ventricular catheter assembly including a proximal catheter and a cooperating cranial cover. The cranial cover includes a base plate having an opening aligned with a burr hole in the skull of a person. A guide extends upwardly from the base plate and receives the proximal catheter.

Disclosed is a valve assembly operable to selectively control a flow or passage of a fluid. The valve assembly may be applied to any appropriate mechanism such as a hydrocephalus shunt, fluid draining sewage system, or tank holding system. The valve assembly disclosed may include a selected profile for various applications.

Systems and methods for draining cerebrospinal fluid (CSF) are described herein described herein. In one implementation, an example system includes a signal generator, a plurality of electrodes operably connected to the signal generator, and a controller operably connected to the signal generator. The controller includes a processor and a memory. The controller is configured to deliver a neuromuscular electrical stimulation signal including at least one burst of pulses to at least one muscle in the subject's neck. The neuromuscular electrical stimulation signal is configured to induce a plurality of contractions of the at least one muscle. Additionally, the contractions of the at least one muscle are configured to squeeze at least one lymph node to create a pumping force, and the pumping force is configured to direct CSF flow in a proximal direction. The results in CSF drainage through the subject's neck lymphatic system.

A valve device monitoring system for at-home human-in-the-loop hydrocephalus shunt monitoring detects degradation and imminent failure of implantable devices for the treatment of hydrocephalus. Potential mechanisms for failure are presented and associated with observable parameters. The valve device monitoring system enables at-home testing using a non-invasive monitoring methodology. Development of a behavioral model of the valve device monitoring system involves a tightly-coupled valve design and behavioral characterization process aimed at reducing unnecessary monetary, material, animal welfare, and computational costs.

Methods for treating hydrocephalus using a shunt, the shunt having one or more CSF intake openings in a distal portion, a valve disposed in a proximal portion of the shunt, and a lumen extending between the one or more CSF intake openings and the valve, the method comprises deploying the shunt in a body of a patient so that the distal portion of the shunt is at least partially disposed within a CP angle cistern, a body of the shunt is at least partially disposed within an IPS of the patient, and the proximal portion of the shunt is at least partially disposed within or proximate to a JV of the patient, wherein, after deployment of the shunt, CSF flows from the CP angle cistern to the JV via the shunt lumen at a flow rate in a range of 5 ml per hour to 15 ml per hour.

Disclosed herein is ureteral stent. The ureteral stent includes a proximal end, a distal end, and a middle portion. The proximal end includes a retention feature having a coiled shape. The distal end is opposite the proximal end. The middle portion is between the proximal end and the distal end.

The present disclosure generally relates to systems and methods of use for draining cerebrospinal fluid (CSF) from a brain or a spinal canal in a subject, for example, to treat hydrocephalus or other conditions. In some embodiments, the disclosure relates to a device comprising a flow controller positioned within a conduit that allows CSF to flow through the conduit from a first end to a second end. This may allow the CSF to drain, for example, from an intradural space (such as a thecal sac) into, for example, a paraspinal space, paraspinal vein or other venous space, or peritoneal cavity. A variety of methods may be used to hold or anchor the device in place, for example, an expansion apparatus. In some embodiments, the device can be implanted percutaneously at a location along or within a subject's spinal column, thus reducing the need for surgery, general anesthesia, and hospitalizations.

The valve has: a body projecting an inlet duct and an outlet duct; a seat in the inlet duct and cooperating with a sealing ball; a helical spring between the sealing ball and a supporting ball; a rotor mounted on the body and having a cam surface, cooperating with the supporting ball; a locking member having a magnet and housed within each cavity of the rotor, and to be moved between operative and inoperative positions; a spring in each cavity and forcing the locking member into the operative position; and retention housings, each of two of the latter being opposite to each other, receiving one of the locking members in the operative position, in a rotational position of the rotor.