There is provided a medicinal liquid injection port to be implanted subcutaneously. A housing main body is provided with a medicinal liquid storage portion therein, an opening portion that opens the medicinal liquid storage portion, and a discharge hole that communicates with the medicinal liquid storage portion and configured to be connected with a tube. A septum attached to the opening portion of the housing main body and provided with a puncturable region that can be punctured with a puncture needle. A contrast portion is disposed in the septum over a thickness direction of the septum so as to detect the puncturable region of the septum with the ultrasonic wave. The contrast portion is provided in the septum within a thickness region of the septum and all of the contrast portion is positioned at an inner side of the septum in the thickness direction of the septum.

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

In some embodiments, a device may include an intraventricular access device and an infusion device. The intraventricular access device may include more than one catheter and a container. In some embodiments, the catheter may include an aspiration lumen and an infusion lumen. A distal end of the intraventricular portion of the catheter may be positionable, during use, in a subject's brain fluid. In some embodiments, the container may be coupled to a proximal end of the aspiration lumen. The proximal end of the aspiration lumen may be in fluid communication with the container. The proximal end of the infusion lumen may be in communication with an infusion pump. In some embodiments, the device inhibits cross contamination between a first fluid in the aspiration lumen and a second fluid in the infusion lumen. In some embodiments, the container may include a barrier positioned between a proximal opening of the aspiration lumen and at least a portion of the infusion lumen adjacent to and/or associated with the container. The barrier may inhibit penetration of a surgical instrument.

Described herein is an implantable device configured to detect impedance characteristic of a tissue. In certain exemplary devices, the implantable device comprises (a) an ultrasonic transducer configured to emit an ultrasonic backscatter encoding information relating to an impedance characteristic of a tissue based on a modulated current flowing through the ultrasonic transducer; (b) an integrated circuit comprising (i) a variable frequency power supply electrically connected to a first electrode and a second electrode; (ii) a signal detector configured to detect an impedance, voltage, or current in a circuit comprising the variable frequency power supply, the first electrode, the second electrode, and the tissue; and (iii) a modulation circuit configured to modulate the current flowing through the ultrasonic transducer based on the detected impedance, voltage, or current; and the first electrode and the second electrode configured to be implanted into the tissue in electrical connection with each other through the tissue. Further described are systems including one or more implantable devices and an interrogator for operating the implantable device, methods of measuring impedance characteristic of a tissue in a subject, and methods of monitoring or characterizing a tissue in a subject.

Apparatus and methods for controlled arterial/venous access are provided. The apparatus and methods may include a lumen anastomosed to a bodily lumen. A lumen clamping means may utilize a clamp manipulator to effectively seal the tubing, and the manipulator may be operated by two fingers. A needle receptor may be utilized, and the receptor may utilize a compressible member to seal tightly against a needle inserted from outside the body, in order ensure secure placement into a channel. The channel may be in liquid communication with the tubing. The manipulator and the needle receptor may be palpable from outside the body.

An access port for subcutaneous implantation is typically connected to a catheter, a distal portion of which is disposed within a vein or other vessel of the patient. The access port described herein is configured with enhanced fluid handling features to improve fluid flow therethrough while reducing the likelihood of clotting or occlusions in the attached catheter, thus improving system patency. The access port includes a body defining a reservoir, a needle-penetrable septum covering the top opening of the reservoir, a stem including a lumen in fluid communication with the reservoir, and a volume control device positioned in the reservoir. The volume control device includes a floor designed to move from a first position below the side opening to a second position adjacent the bottom surface, and a spring element positioned between the floor and the bottom surface, the spring element biasing the floor in the first position.

A tissue expander having an integrated drain includes a shell having an opening and one or more drainage holes, and an injection port disposed in the opening of the shell and forming a fluid-tight seal with the shell. The injection port includes a needle guard having a needle guard base with a top surface. The injection port includes a moveable barrier membrane overlying the top surface of the needle guard base. The moveable barrier membrane is moveable between a first position for inflating and deflating the shell with a first fluid and a second position for draining a second fluid from outside the shell. A magnet is coupled with the moveable barrier membrane, and a compressible spring is connected with the magnet. The compressible spring is compressed for storing energy as the moveable barrier membrane moves from the first position to the second position.

A variable volume infusion port is provided. The infusion port may include a port body having an internal fluid reservoir, a septum, a stem to fluidly couple to a catheter lumen, and a displaceable member disposed in the internal fluid reservoir. In a first position, the displaceable member is disposed proximate the septum, providing a relatively small fluid volume within the infusion port. Insertion of an injection device through the septum causes the displaceable member to move to a second location distal from the septum, providing a relatively large fluid volume within the infusion port for the duration the injection device remains in the infusion port. The displaceable member may include a rigid member operably coupled to a biasing element or a flexible member coupled to a biasing element.

A vascular access device with arteriovenous fistula support includes a top portion and a bottom portion. The top portion has a partial artery channel, a partial vessel channel, and a partial arteriovenous joint between the partial artery channel and the partial vessel channel, where the partial vessel channel has a vascular access aperture for exposing the vessel. The bottom portion has a corresponding partial artery channel, partial vessel channel, and partial arteriovenous joint between the partial artery channel and the partial vessel channel. When the top portion is coupled to the bottom portion, the two partial artery channels couple together to form an artery channel, the two partial vessel channels couple together to form a vessel channel, and the two partial arteriovenous joints couple together to form an arteriovenous joint for an arteriovenous fistula.

The present disclosure provides medical devices, particularly medical grade needles with removable tips, as well as methods of needle tip installation and removal, and devices therefor. Needle tip installation and removal devices may include needle tip installation and removal tools and kits, including hand held and manipulated tools that facilitate the installation and removal of needle tips, particularly on vascular access port needles. Such installation and removal devices may provide more expedient hook up of the access port for the therapy. Also, the installation and removal of the needle tips may be conducted in a more sterile manner.