A medical device is adapted to seal around elongate shafts of varying diameter therethrough. The medical device includes a plurality of elastomeric sealing members together defining a variable dimension aperture, a chuck body, and a chuck ring that is rotatably secured relative to the chuck body. The medical device is adapted such that rotating the chuck ring in a first direction causes the plurality of elastomeric sealing members to move closer together, thereby reducing a size of the variable dimension aperture, and rotating the chuck ring in a second direction causes the plurality of elastomeric sealing members to move farther apart, thereby increasing a size of the variable dimension aperture.

Devices, systems, and methods for sealing medical devices, particularly during intravascular access, are disclosed herein. Some aspects relate to a hemostatic valve for sealing a wide range of medical devices, such as catheters, wires, embolectomy systems. The valve can include an elongate member having a first end, a second end, and a central lumen extending therebetween. A reinforcement structure extends along at least a portion of the elongate member and is coupled to the elongate member. A shell defining a first aperture and a second aperture may be included, which first and second apertures can be fluidly coupled by the elongate member. A tensioning mechanism is coupled to the shell and to the elongate member, the tensioning mechanism can be moveable between a first configuration wherein the tensioning mechanism is collapsed and the central lumen is sealed and a second configuration wherein the central lumen is open.

A vasculature navigation system may include a dilator having a proximal end and a distal end located opposite the proximal end, the dilator comprising a guidewire lumen extending between the proximal end and the distal end, the dilator defining a proximal portion and a distal portion located opposite the proximal portion. In some embodiments, the vasculature navigation system also includes an access port located at the proximal end of the dilator, a distal port located at the distal end of the dilator, and a hemostasis valve coupled to the proximal portion of the dilator. The hemostasis valve may be configured to control fluid flow between the proximal portion and the distal portion. In some embodiments, a flush port is coupled to the proximal portion of the dilator and located distal to the hemostasis valve, and the flush port is coupled to a fluid supply source.

A vasculature navigation system may include a dilator having a proximal end and a distal end located opposite the proximal end, the dilator comprising a guidewire lumen extending between the proximal end and the distal end, the dilator defining a proximal portion and a distal portion located opposite the proximal portion. In some embodiments, the vasculature navigation system also includes an access port located at the proximal end of the dilator, a distal port located at the distal end of the dilator, and a hemostasis valve coupled to the proximal portion of the dilator. The hemostasis valve may be configured to control fluid flow between the proximal portion and the distal portion. In some embodiments, a flush port is coupled to the proximal portion of the dilator and located distal to the hemostasis valve, and the flush port is coupled to a fluid supply source.

Blood sample optimization systems and methods are described that reduce or eliminate contaminates in collected blood samples, which in turn reduces or eliminates false positive readings in blood cultures or other testing of collected blood samples. A blood sample optimization system can include a blood sequestration device located between a patient needle and a sample needle. The blood sequestration device can include a sequestration chamber for sequestering an initial, potentially contaminated aliquot of blood, and may further include a sampling channel that bypasses the sequestration chamber to convey likely uncontaminated blood between the patient needle and the sample needle after the initial aliquot of blood is sequestered in the sequestration chamber.

A hub for an optical shape sensing reference includes a hub body (606) configured to receive an elongated flexible instrument (622) with a shape sensing system coupled to the flexible instrument within a path formed in the hub body. A profile (630) is formed in the hub body in the path to impart a hub template configured to distinguish a portion of the elongated flexible instrument within the hub in shape sensing data. An attachment mechanism (616) is formed on the hub body to detachably connect the hub body to a deployable instrument such that a change in a position of the hub body indicates a corresponding change in the deployable device.

A hub for an optical shape sensing reference includes a hub body (606) configured to receive an elongated flexible instrument (622) with a shape sensing system coupled to the flexible instrument within a path formed in the hub body. A profile (630) is formed in the hub body in the path to impart a hub template configured to distinguish a portion of the elongated flexible instrument within the hub in shape sensing data. An attachment mechanism (616) is formed on the hub body to detachably connect the hub body to a deployable instrument such that a change in a position of the hub body indicates a corresponding change in the deployable device.

A surgical access device includes a seal assembly having a seal housing and a gimbal mount disposed within the seal housing, the seal housing defining a central longitudinal axis and having a longitudinal passage for receiving at least one surgical object therethrough and the gimbal mount adapted for angular movement relative to the central longitudinal axis. The surgical access device also includes a bellows configured to engage at least a portion of the gimbal mount, the bellows dimensioned and adapted to establish a biasing relationship with the gimbal mount, such that the bellows overcomes a frictional relationship between the gimbal mount and the seal housing, thereby moving the gimbal mount towards a position in which the passage of the gimbal mount is aligned with the central longitudinal axis. The bellows is configured to be attached to a side wall of the seal housing.

A surgical access device includes a seal assembly having a seal housing and a gimbal mount disposed within the seal housing, the seal housing defining a central longitudinal axis and having a longitudinal passage for receiving at least one surgical object therethrough and the gimbal mount adapted for angular movement relative to the central longitudinal axis. The surgical access device also includes a bellows configured to engage at least a portion of the gimbal mount, the bellows dimensioned and adapted to establish a biasing relationship with the gimbal mount, such that the bellows overcomes a frictional relationship between the gimbal mount and the seal housing, thereby moving the gimbal mount towards a position in which the passage of the gimbal mount is aligned with the central longitudinal axis. The bellows is configured to be attached to a side wall of the seal housing.

A method of manufacturing a seal assembly for a surgical access assembly includes forming a seal assembly having a monolithic construction. The seal assembly includes a support member, seal sections connected to the support member, bridges disposed between adjacent seal sections and interconnecting the adjacent seal sections, and a plurality of standoffs extending from each seal section. The method also includes placing the seal assembly into a treatment bath, cutting the bridges, and folding the seal assembly.