The present invention comprises methods and devices for generating and providing contrast medium for sonography of structures such as ducts or cavities. The invention provides for creation of a contrast medium comprising detectable acoustic variations between two phases, for example, a gas and a liquid. Sonography is the primary means of imaging but other conventional detection means may also be employed with the present invention.

A housing includes a cavity portion and a cover portion configured for rotary motion. The cover portion can include a receiver port configured to engage with a fitting configured for coupling to an end of a first tube. At a first alignment position of the cavity portion relative to the cover portion, the receiver port is aligned with a first retention cleat. At a second alignment position of the cavity portion relative to the cover portion, the receiver port is aligned with a fluid coupler. At a third alignment position of the cavity portion relative to the cover portion, the fitting is aligned with a second cap.

The present teachings include techniques for securing a connection to a dialyzer or the like—e.g., securing the junction between a dialyzer port and a connector (e.g., a DIN connector) that couples the port to tubing of an extracorporeal circuit of a hemodialysis system. To this end, a locking device may engage both a DIN connector and a portion of the dialyzer, such as the cap or an adapter engaged therewith. The locking device may include an interior void sized and shaped to accommodate winged portions (or other portions) of the DIN connector to mitigate rotation thereof relative to the port to which it is engaged. Further, the locking device may be used to ensure that coupling between the DIN connector and the port is proper and secure. In this manner, a locking device can mitigate leaks, which can be catastrophic during a hemodialysis treatment or the like.

Provided herein is an intravascular catheter assembly, including a catheter adapter having a distal end, a proximal end, a lumen arranged between and in fluid communication with the distal end and the proximal end, a catheter arranged at the distal end of the catheter adapter and in fluid communication with the lumen, and a side port in fluid communication with the lumen. The assembly further includes a fluid conduit having a distal end and a proximal end, the distal end of the fluid conduit coupled to the side port, a connector arranged at the proximal end of the fluid conduit, and an occlusion device configured to stop flow through the fluid conduit.

Disclosed herein is an intravascular catheter assembly, including a catheter adapter having a distal end; a proximal end; a first lumen arranged between and in fluid communication with the distal end and the proximal end; a catheter arranged at the distal end of the catheter adapter and in fluid communication with the lumen; and a first side port in fluid communication with the lumen; a first fluid conduit having a distal end and a proximal end, the distal end of the fluid conduit coupled to the side port; and a connector having a proximal end, a distal end connected to the fluid conduit, and a second lumen therethrough, the connector comprising a manually-actuable valve.

A device for filling a reservoir. The device includes a cover portion comprising a septum window, and a bottom portion, the bottom portion configured to attach to a disposable housing assembly comprising the reservoir, wherein the cover portion and the bottom portion are rotatably attached in a locked configuration and wherein in a locked configuration, a septum is obscured through the septum window, wherein when the cover portion and the bottom portion are placed in an unlocked configuration, the cover portion rotates with respect to the bottom portion and the septum is visible through the septum window.

Apparatuses, methods, and systems are disclosed for securing a tube to a tube insertion site. An apparatus for a medical tube securement device includes a base member and a clamp member. The base member includes a first tab portion, a second tab portion, and an opening for receiving a tube. The opening is located substantially between the first tab portion and the second tab portion. A clamp member secures the tube within the opening to prevent the tube from moving while the base member is attached to a person and the tube is located at a tube insertion site on the person.

Systems and methods are disclosed that include a guide catheter apparatus insertable through a external body passage of a subject. The guide catheter apparatus includes a substantially rigid shaft and a handle. The shaft has a proximal opening, a distal opening, and a lumen extending between the proximal opening and the distal opening. The handle has a structure to allow a position of the guide catheter to be controlled by some or all of three fingers of one hand of an operator of the handle. The structure of the handle is adapted to permit the operator to position a thumb and index finger of the hand to manipulate a working device inserted into the lumen of the guide catheter, where the working device is manipulable via a portion of the working device immediately adjacent to the handle.

There is disclosed a fluid distribution system for distributing fluid from a single source to a plurality of downstream receptacles. The system has a distribution manifold with a single inlet and a plurality of outlets arrayed around a circumferential outer periphery. The outlets may be directed to the different receptacles which each have their own vent filter, or each receptacle connects back to the distribution manifold for common venting.

A medical device may include a body and a photosensitizer integrated with the body. The medical device may passively resist colonization of bacteria under ambient light. The medical device may also actively resist colonization of bacteria by releasing reactive oxidative species (ROS) in response to administration of a light dose in a range of 0.5 J/cm.sup.2 to 320 J/cm.sup.2, for a duration between 1 second and 1 hour. The body may be formed by a base resin. The photosensitizer may be compounded with the base resin. The photosensitizer may be imbibed into the base resin. The medical device may include a coating disposed on a surface of the body. The photosensitizer may be disposed within the coating. The medical device may include a catheter adapter and a catheter extending distally from the catheter adapter. The catheter may be co-extruded with the photosensitizer and another material.