A coupler of a valve assembly for coupling a flow control valve to an infusion device. The coupler includes a proximal portion and a distal portion. The proximal portion comprises a plurality of recessed segments configured for receiving the infusion device. The distal portion comprises a valve flange that defines a central cavity for receiving the flow control valve. The valve flange comprises a swage extending radially inward to the central cavity for mechanically engaging a luer lock fitting of the valve assembly.

Some embodiments disclosed herein relate to medical connectors with a housing comprising a proximal body member and a base member that form an internal cavity with a proximal abutment surface. An elastomeric seal without a guide member is positioned within the internal cavity. A rigid, hollow elongated portion is located within the internal cavity such that in an open configuration, a tip of the elongated portion is more proximal than a proximal surface of the elastomeric seal. A distal portion of the elastomeric seal is seated radially within a region surrounded by a plurality of longitudinally extending protrusions.

A medical female connector (10) for controlling a fluid flow is disclosed, as well as a method for its manufacturing, and medical devices including such a female connector. A tubular plunger (40) and a flexible valve member (60) are inserted into a housing (20). A distal end (42) of the plunger (40) is located at a distance proximally from the distal end (22) of the housing (20). In a flow stop configuration, the flexible valve member (60) seals a flow path (44) through the tubular plunger (40). In a flow configuration, the valve member (60) is compressed by a male connector (90) and deformed by the plunger (40) to allow a fluid flow through the plunger (40). A frusto-conical female sealing surface (24) is arranged to form a seal with the male connector (90). An entrance opening (25) of the housing (20) presents a diameter equal to or larger than the maximum diameter (d1) of the female sealing surface (24).

A medical female connector (10) for controlling a fluid flow is disclosed, as well as a method for its manufacturing, and medical devices including such a female connector. A tubular plunger (40) and a flexible valve member (60) are inserted into a housing (20). A distal end (42) of the plunger (40) is located at a distance proximally from the distal end (22) of the housing (20). In a flow stop configuration, the flexible valve member (60) seals a flow path (44) through the tubular plunger (40). In a flow configuration, the valve member (60) is compressed by a male connector (90) and deformed by the plunger (40) to allow a fluid flow through the plunger (40). A frusto-conical female sealing surface (24) is arranged to form a seal with the male connector (90). An entrance opening (25) of the housing (20) presents a diameter equal to or larger than the maximum diameter (d1) of the female sealing surface (24).

In some embodiments, a medical fluid connector is configured to receive an emitter of therapeutic agents to be emitted into a fluid pathway within the connector, the medical fluid connector comprising a proximal female end, an intermediate region, a distal male end, and a fluid pathway extending from the proximal female end, through the intermediate region, to the distal male end. A retaining structure is positioned within the intermediate region. The retaining structure is configured to securely receive an emitter of one or more therapeutic agents in a position and orientation where the fluid pathway is configured to convey fluid moving longitudinally through the fluid pathway directly into a proximal region of the emitter, around one or more lateral surfaces of the emitter, and toward the distal male end.

In some embodiments, a medical fluid connector is configured to receive an emitter of therapeutic agents to be emitted into a fluid pathway within the connector, the medical fluid connector comprising a proximal female end, an intermediate region, a distal male end, and a fluid pathway extending from the proximal female end, through the intermediate region, to the distal male end. A retaining structure is positioned within the intermediate region. The retaining structure is configured to securely receive an emitter of one or more therapeutic agents in a position and orientation where the fluid pathway is configured to convey fluid moving longitudinally through the fluid pathway directly into a proximal region of the emitter, around one or more lateral surfaces of the emitter, and toward the distal male end.

A needleless valve system includes a cannula comprising a cannula tip; a valve comprising a valve tip, wherein the valve is disposed around the cannula; and a housing comprising a housing tip, wherein the cannula tip, the valve tip, and the housing tip comprise a flat surface when the needleless valve system is in a sealed position.

A needleless valve system includes a cannula comprising a cannula tip; a valve comprising a valve tip, wherein the valve is disposed around the cannula; and a housing comprising a housing tip, wherein the cannula tip, the valve tip, and the housing tip comprise a flat surface when the needleless valve system is in a sealed position.

Methods and devices to facilitate positioning of a catheter into a vessel. Devices include axially concentric assemblies of a piercing needle and a dilator that guides an outer catheter into a vessel, such as a blood vessel. The assemblies described herein can include retraction mechanisms and/or lock mechanisms to control needle positioning during catheterization processes as well as improved valves that prevent leakage of fluid from the proximal end of the devices. The devices and method include the use of novel valves to prevent undesired leakage of fluids through the proximal end of the catheter.

Methods and devices to facilitate positioning of a catheter into a vessel. Devices include axially concentric assemblies of a piercing needle and a dilator that guides an outer catheter into a vessel, such as a blood vessel. The assemblies described herein can include retraction mechanisms and/or lock mechanisms to control needle positioning during catheterization processes as well as improved valves that prevent leakage of fluid from the proximal end of the devices. The devices and method include the use of novel valves to prevent undesired leakage of fluids through the proximal end of the catheter.