A system for improving blood flow through a circulatory system of a patient is disclosed. The patient can have a wrist. The circulatory system can have a radial artery, an ulnar artery, and a descending aorta. The system can comprise at least one inflatable bladder that is configured to be received into the descending aorta of the patient. A pump can be configured to cyclically pump a fluid into the at least one inflatable bladder to inflate the at least one inflatable bladder. A conduit can be positioned between and in fluid communication with the at least one inflatable bladder and the pump. The conduit can be configured to communicate the fluid between the pump and the at least one inflatable bladder. The conduit can have a length of at least 110 cm.

A device to reduce left ventricle afterload in a target blood vessel in a mammal includes a cushion configured for positioning within a lumen of the target blood vessel and receipt of a fluid and configured to contract during systole and expand during diastole, a reservoir having a cavity for receiving the fluid, and a conduit extending between and fluidically coupling the cushion and the reservoir, whereby during use fluid in the cushion is transferred to the reservoir during systole and returned to the cushion during diastole. The cushion has an annular cross section defining a central lumen for blood flow and is configured for positioning in the lumen of the target vessel abutting an inner wall of the target vessel, whereby during use blood flow is directed through the central lumen of the cushion.

A device to reduce left ventricle afterload in a target blood vessel in a mammal includes a cushion configured for positioning within a lumen of the target blood vessel and receipt of a fluid and configured to contract during systole and expand during diastole, a reservoir having a cavity for receiving the fluid, and a conduit extending between and fluidically coupling the cushion and the reservoir, whereby during use fluid in the cushion is transferred to the reservoir during systole and returned to the cushion during diastole. The cushion has an annular cross section defining a central lumen for blood flow and is configured for positioning in the lumen of the target vessel abutting an inner wall of the target vessel, whereby during use blood flow is directed through the central lumen of the cushion.

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

A system for treating heart disease, such as pulmonary hypertension or right heart failure, including an implantable component and external components for monitoring the implantable component is provided. The implantable component may include a compliant member, e.g., balloon, coupled to a reservoir via a conduit. Preferably, the compliant member is adapted to be implanted in a pulmonary artery and the reservoir is adapted to be implanted subcutaneously. The external components may include a clinical controller component, monitoring software configured to run a clinician's computer, a patient monitoring device, and a mobile application configured to run on a patient's mobile device.

The cardiovascular device (1) comprises a diaphragm assembly designed to be inserted into a ventricular cavity (VS) substantially transverse in order to reduce its volume, said diaphragm assembly having a peripheral edge (2B) that can be sealingly engaged on the walls (5) of the cavity 7 and being alternately driven between an active blood thrust position and an inactive position, said assembly being at least partially deformable in response to contractions of the walls (5) and comprising a balloon-shaped elastic body (2; 100; 200; 300; 400) which has an external surface (2A; 103) that defines and encloses an internal cavity (CI; CI2) and which can be configured between a gathered position of minimum bulk, an everted position of maximum bulk and vice-versa, at least one mobile portion (3; 3′) of the peripheral surface which is disposed transverse/diagonal and which is surrounded by the peripheral edge and at least one aperture (3A) for access from the outside to the internal cavity (CI; CI2).

The cardiovascular device (1) comprises a diaphragm assembly designed to be inserted into a ventricular cavity (VS) substantially transverse in order to reduce its volume, said diaphragm assembly having a peripheral edge (2B) that can be sealingly engaged on the walls (5) of the cavity 7 and being alternately driven between an active blood thrust position and an inactive position, said assembly being at least partially deformable in response to contractions of the walls (5) and comprising a balloon-shaped elastic body (2; 100; 200; 300; 400) which has an external surface (2A; 103) that defines and encloses an internal cavity (CI; CI2) and which can be configured between a gathered position of minimum bulk, an everted position of maximum bulk and vice-versa, at least one mobile portion (3; 3′) of the peripheral surface which is disposed transverse/diagonal and which is surrounded by the peripheral edge and at least one aperture (3A) for access from the outside to the internal cavity (CI; CI2).

A catheter directionally conducts a pulsating body fluid and has a line segment defining an inner volume. A pump chamber section is arranged proximally as an extension of the line segment and defines a pump chamber having a frame therein accommodating a balloon. A first opening connects the inner volume to an external volume and a second opening is arranged proximally from the first opening to connect the inner volume to the external volume. A check valve is assigned to the second opening and the check valve includes a valve foil having an aperture formed therein offset from the second opening. A third opening communicates with the pump chamber. The frame is of a shape memory material which provides rigidity for a pulsatile operation of the balloon. During operation, the pulsating body fluid is conveyed in the inner volume directionally between the first and second opening by operating the balloon.

A catheter directionally conducts a pulsating body fluid and has a line segment defining an inner volume. A pump chamber section is arranged proximally as an extension of the line segment and defines a pump chamber having a frame therein accommodating a balloon. A first opening connects the inner volume to an external volume and a second opening is arranged proximally from the first opening to connect the inner volume to the external volume. A check valve is assigned to the second opening and the check valve includes a valve foil having an aperture formed therein offset from the second opening. A third opening communicates with the pump chamber. The frame is of a shape memory material which provides rigidity for a pulsatile operation of the balloon. During operation, the pulsating body fluid is conveyed in the inner volume directionally between the first and second opening by operating the balloon.

Some embodiments of a system or method for treating heart tissue can include a control system and catheter device operated in a manner to intermittently occlude a heart vessel for controlled periods of time that provide redistribution of blood flow. In particular embodiments, the system and methods may be configured to monitor at least one input signal detected at a coronary sinus and thereby execute a process for determining a satisfactory time period for the occlusion of the coronary sinus. In further embodiments, after the occlusion of the coronary sinus is released, the control system can be configured to select the duration of the release phase before the starting the next occlusion cycle.