This invention is a system to assist human cardiovascular functioning which integrates the operation of an implanted cardiac device and a wearable device with an arcuate array of biometric sensors. Analysis of data from the biometric sensors on the wearable device is used to automatically adjust and optimize the operation of the implanted cardiac device. This system can work as a closed loop system for assisting and improving human cardiovascular functioning.

Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

A bidirectional intravascular blood pump system is disclosed for deployment in the descending aorta to improve perfusion in both upper and lower extremities. In some embodiments, the system includes a flexible stent housing containing an inflatable pump chamber and selectively inflatable proximal and distal check valves. In some embodiments, a controller sequences inflation and deflation of the pump components in coordination with the cardiac cycle. In some embodiments, the system capable of dynamically providing flow in opposite directions within the descending aorta to optimize systemic and cerebral perfusion. In some embodiments, the system can direct blood flow in either direction through the aorta by an inflation sequence of the check valves and pump chamber. In some embodiments, one or more bypasses in a check element, stent, and/or formed from selective inflation, enable pressurization of the aortic arch when timed with the closing of the aortic valve.

A bidirectional intravascular blood pump system is disclosed for deployment in the descending aorta to improve perfusion in both upper and lower extremities. In some embodiments, the system includes a flexible stent housing containing an inflatable pump chamber and selectively inflatable proximal and distal check valves. In some embodiments, a controller sequences inflation and deflation of the pump components in coordination with the cardiac cycle. In some embodiments, the system capable of dynamically providing flow in opposite directions within the descending aorta to optimize systemic and cerebral perfusion. In some embodiments, the system can direct blood flow in either direction through the aorta by an inflation sequence of the check valves and pump chamber. In some embodiments, one or more bypasses in a check element, stent, and/or formed from selective inflation, enable pressurization of the aortic arch when timed with the closing of the aortic valve.

Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

Perfusion systems and methods are provided for increasing peripheral blood flow to reduce limb ischemia, in which an extracorporeal pump having a controller, and catheter/tubing set, employed alone or in conjunction with an interventional or circulatory assist device, withdraws blood from a patient's vasculature and reintroduces that blood at another location within the patient's vasculature at a controlled local pressure or flow rate, without interfering with operation of the interventional or circulatory assist device or surgical intervention.

An antegrade perfusion assembly may have a braided sheath, a three-way stopcock, and a male-to-male connection. The three-way stopcock can fluidly communicate with the braided sheath in assembly. The three-way stopcock can furnish control of perfusate flow amid use of the antegrade perfusion assembly, and can facilitate de-airing of the braided sheath amid use of the antegrade perfusion assembly. The male-to-male connection can fluidly communicate with the three-way stopcock, and can accept reception and securement with an oxygenated blood source amid use of the antegrade perfusion assembly.

An antegrade perfusion assembly may have a braided sheath, a three-way stopcock, and a male-to-male connection. The three-way stopcock can fluidly communicate with the braided sheath in assembly. The three-way stopcock can furnish control of perfusate flow amid use of the antegrade perfusion assembly, and can facilitate de-airing of the braided sheath amid use of the antegrade perfusion assembly. The male-to-male connection can fluidly communicate with the three-way stopcock, and can accept reception and securement with an oxygenated blood source amid use of the antegrade perfusion assembly.