A surgical kit for repairing an aortic aneurysm comprising a vascular prosthesis with a primary conduit forming a primary lumen extending from a primary inlet opening to a primary outlet opening, and a perfusion branch conduit forming a perfusion branch lumen extending from a perfusion branch opening in the primary conduit to a perfusion outlet opening at a distal end of the perfusion branch conduit; and a perfusion apparatus comprising an inlet conduit having a proximal end configured to be fluidly coupled to the distal end of the perfusion branch conduit, a plurality of secondary conduits branching from the inlet conduit and configured for fluid coupling to aortic branches, and a valve assembly configured to selectably alter the plurality of secondary conduits between an open flow state and a closed sealed state.

A method of providing ventricular support for a human patient during a high-risk percutaneous coronary intervention procedure includes inserting a mechanical circulatory support device into the vasculature of a human patient. The mechanical circulatory support device being movable between a compressed state and an expanded state. The mechanical circulatory support device is delivered into a heart of the human patient with the aid of a delivery assist device. Operating. The mechanical circulatory support device is operated for a support period. A clinically significant arrhythmia adverse event (AE) associated with the mechanical circulatory support device experiencing the arrhythmia event between the time of vascular access with the mechanical circulatory support device and removal of the mechanical circulatory support device from the vasculature is approximately 2.3%.

A method of providing ventricular support for a human patient during a high-risk percutaneous coronary intervention procedure includes inserting a mechanical circulatory support device into the vasculature of a human patient. The mechanical circulatory support device being movable between a compressed state and an expanded state. The mechanical circulatory support device is delivered into a heart of the human patient with the aid of a delivery assist device. Operating. The mechanical circulatory support device is operated for a support period. A clinically significant arrhythmia adverse event (AE) associated with the mechanical circulatory support device experiencing the arrhythmia event between the time of vascular access with the mechanical circulatory support device and removal of the mechanical circulatory support device from the vasculature is approximately 2.3%.

Embodiments herein provide a Pulmonary Circulation Assist Implant for passively regulating the cardiovascular blood flow in a subject born with a univentricular heart. The Pulmonary Circulation Assist Implant is configured to avoid a head-on collision between the bloodstreams from a Superior Vena Cava (SVC) and an Inferior Vena Cava (IVC) without an offset between them. Further, the Pulmonary Circulation Assist Implant is configured to smoothly distribute the SVC blood and IVC hepatic blood to both lungs in equal proportions without swirling. Also, the Pulmonary Circulation Assist Implant is configured to avoid the occurrence of retrograde flow and reduce power loss.

The circulation assist devices disclosed herein can be used, for example, in methods of decreasing venous pressure in the Fontan circulation. The devices can include an inlet, an outlet, a stator, a rotor, and an impeller driven by rotation of the rotor. In some embodiments, the impeller blade (or blades) can at least partially define a central lumen extending through the device. The device can be coupled to the inferior vena cava and the pulmonary artery. Rotating the impeller blade(s) increases blood velocity through the lumen and causes the outlet pressure to be higher than the inlet pressure. The impeller can be configured such that, when it is stationary, the forward static pressure drop between the inlet and the outlet is minimized. That is, the forward static pressure drop of the device approximates the pressure drop between the inferior vena cava and central pulmonary artery of the unassisted Fontan circulation.

The circulation assist devices disclosed herein can be used, for example, in methods of decreasing venous pressure in the Fontan circulation. The devices can include an inlet, an outlet, a stator, a rotor, and an impeller driven by rotation of the rotor. In some embodiments, the impeller blade (or blades) can at least partially define a central lumen extending through the device. The device can be coupled to the inferior vena cava and the pulmonary artery. Rotating the impeller blade(s) increases blood velocity through the lumen and causes the outlet pressure to be higher than the inlet pressure. The impeller can be configured such that, when it is stationary, the forward static pressure drop between the inlet and the outlet is minimized. That is, the forward static pressure drop of the device approximates the pressure drop between the inferior vena cava and central pulmonary artery of the unassisted Fontan circulation.