A pump for mimicking physiological blood flow in a patient is disclosed. The pump works via compression and decompression of a tube, inducing a peristaltic flow within the tube. The compression may be effected by a linear actuator, or alternatively by a pivoting compression member. A one-way check valve ensures flow in a single direction.

Methods of using an intracardiac blood pump in association with medical procedures. In some cases, patients may be turned down for a medical procedure based on a risk that the procedure itself may cause the patient to experience a cardiac event during and/or following the procedure. In some examples, an intracardiac blood pump may be used to support the heart before, during, and/or after the medical procedure so as to minimize such risks, and thus enable the patient to receive critical treatment that might otherwise be denied.

Methods of using an intracardiac blood pump in association with medical procedures. In some cases, patients may be turned down for a medical procedure based on a risk that the procedure itself may cause the patient to experience a cardiac event during and/or following the procedure. In some examples, an intracardiac blood pump may be used to support the heart before, during, and/or after the medical procedure so as to minimize such risks, and thus enable the patient to receive critical treatment that might otherwise be denied.

A catheter pump is disclosed. The catheter pump can include an impeller and a catheter body having a lumen in which waste fluid flows proximally therethrough during operation of the catheter pump. The catheter pump can also include a drive shaft disposed inside the catheter body. A motor assembly can include a chamber. The motor assembly can include a rotor disposed in the at least a portion of the chamber, the rotor mechanically coupled with a proximal portion of the drive shaft such that rotation of the rotor causes the drive shaft to rotate, the rotor including a longitudinal rotor lumen therethrough. The motor assembly can also comprise a stator assembly disposed about the rotor. During operation of the catheter pump, the waste fluid flows from the lumen into the chamber such that at least a portion of the waste fluid flows proximally through the longitudinal rotor lumen.

A catheter pump is disclosed. The catheter pump can include an impeller and a catheter body having a lumen in which waste fluid flows proximally therethrough during operation of the catheter pump. The catheter pump can also include a drive shaft disposed inside the catheter body. A motor assembly can include a chamber. The motor assembly can include a rotor disposed in the at least a portion of the chamber, the rotor mechanically coupled with a proximal portion of the drive shaft such that rotation of the rotor causes the drive shaft to rotate, the rotor including a longitudinal rotor lumen therethrough. The motor assembly can also comprise a stator assembly disposed about the rotor. During operation of the catheter pump, the waste fluid flows from the lumen into the chamber such that at least a portion of the waste fluid flows proximally through the longitudinal rotor lumen.

A heart pump includes a cannula having a sidewall defining a longitudinal blood flow passage and a plurality of outlets extending through the sidewall. A rotatable impeller hub includes at least one impeller blade, wherein the at least one impeller blade is shaped to convey blood through the blood flow passage toward the plurality of outlets when the impeller hub is rotated at an operational speed. A diffuser defines an outer, flow directing surface having a geometry that is configured to control at least one property of the conveyed blood prior to flowing through the plurality of outlets.

A heart pump includes a cannula having a sidewall defining a longitudinal blood flow passage and a plurality of outlets extending through the sidewall. A rotatable impeller hub includes at least one impeller blade, wherein the at least one impeller blade is shaped to convey blood through the blood flow passage toward the plurality of outlets when the impeller hub is rotated at an operational speed. A diffuser defines an outer, flow directing surface having a geometry that is configured to control at least one property of the conveyed blood prior to flowing through the plurality of outlets.

A pneumatic system for a medical fluid machine operating a medical fluid cassette, the pneumatic system including an interface for supplying positive pneumatic pressure and negative pneumatic pressure to the medical fluid cassette; a source of positive pneumatic pressure; a source of negative pneumatic pressure; and a pneumatic pump including a first head and a second head, wherein the first head is dedicated to supplying positive pneumatic pressure to the positive pneumatic pressure source and the second head is dedicated to supplying negative pneumatic pressure to the negative pneumatic pressure source.

A heart pump is disclosed herein. The heart pump can include a cannula having one or more outlets. An impeller can be positioned in the cannula. The impeller can be configured to pump blood through the outlets along a longitudinal axis when the impeller is rotated at an operational speed. The heart pump can be configured to adjust an effective area of the outlets while the impeller is rotating or to provide relative motion between the cannula and the impeller along the longitudinal axis while the impeller is rotating.

A controller for a blood pump, in particular a catheter-based intravascular blood pump, configured to utilize detected or determined aortic pressures and left ventricular pressures in order to calculate a coupling factor, which is then used to determine how to adjust the rotational speed of the blood pump, such as when the blood pump is used in conjunction with ECMO devices.