A patient interface to deliver a flow of air at a positive pressure with respect to ambient air pressure to an entrance to the patient's airways to ameliorate sleep disordered breathing includes a frame assembly and a cushion assembly configured to removably and repeatably connect to the frame assembly. The frame assembly and the cushion assembly form at least part of a plenum chamber pressurizable to a therapeutic pressure. The cushion assembly comprises a one-piece construction including a seal-forming structure configured to form a seal with a region of a patients face surrounding the entrance to the patients airways and a frame connection structure configured to removably and repeatably connect the cushion assembly to the frame assembly. The seal-forming structure comprises a first elastomeric material and the frame connection structure comprises a second elastomeric material, the first elastomeric material comprising a lower durometer or hardness than the second elastomeric material.

A patient interface to deliver a flow of air at a positive pressure with respect to ambient air pressure to an entrance to the patient's airways to ameliorate sleep disordered breathing includes a frame assembly and a cushion assembly configured to removably and repeatably connect to the frame assembly. The frame assembly and the cushion assembly form at least part of a plenum chamber pressurizable to a therapeutic pressure. The cushion assembly comprises a one-piece construction including a seal-forming structure configured to form a seal with a region of a patients face surrounding the entrance to the patients airways and a frame connection structure configured to removably and repeatably connect the cushion assembly to the frame assembly. The seal-forming structure comprises a first elastomeric material and the frame connection structure comprises a second elastomeric material, the first elastomeric material comprising a lower durometer or hardness than the second elastomeric material.

A tissue containment system includes a bag body, a member extending from the bag body and defining a channel, and a viewing window. The bag body at least partially defines an interior region configured to contain a loose tissue specimen and defines an opening sized to receive the loose tissue specimen. The bag body is configured such that a first portion of the bag body can be disposed in an abdominal cavity of a patient while a second portion of the bag body extends outside of the patient. The viewing window is at least partially transparent and provides a seal between the interior region of the bag body and an ambient environment. The channel of the member is configured to receive a tissue visualization device that can be used to view the interior region of the containment bag through the viewing window.

A tissue containment system includes a bag body, a member extending from the bag body and defining a channel, and a viewing window. The bag body at least partially defines an interior region configured to contain a loose tissue specimen and defines an opening sized to receive the loose tissue specimen. The bag body is configured such that a first portion of the bag body can be disposed in an abdominal cavity of a patient while a second portion of the bag body extends outside of the patient. The viewing window is at least partially transparent and provides a seal between the interior region of the bag body and an ambient environment. The channel of the member is configured to receive a tissue visualization device that can be used to view the interior region of the containment bag through the viewing window.

A handheld therapeutic apparatus and method of treatment are disclosed. In one example, the apparatus includes a valve system, a detachable gas cartridge housing unit that houses a gas cartridge or gas delivery from an outside gas cylinder in fluid communication with said valve system, a detachable treatment receptacle for the delivery of gas therapies is in fluid communication with said valve system, and a detachable nozzle in fluid communication with said valve system.

A personal breathing apparatus installed in an aircraft that is not fully pressurized, and configured to prevent or treat an adverse physiological event. The personal breathing system is configured so as to prevent, lessen or reverse hypercapnia by (i) facilitating removal of carbon dioxide generated the pilot by controlling pilot ventilation and/or (ii) limiting or decreasing the amount of carbon dioxide generated by the pilot by controlling the amount of oxygen breathed by the pilot.

A personal breathing apparatus installed in an aircraft that is not fully pressurized, and configured to prevent or treat an adverse physiological event. The personal breathing system is configured so as to prevent, lessen or reverse hypercapnia by (i) facilitating removal of carbon dioxide generated the pilot by controlling pilot ventilation and/or (ii) limiting or decreasing the amount of carbon dioxide generated by the pilot by controlling the amount of oxygen breathed by the pilot.

A method and system to manage a respiratory condition of a patient. An oxygen concentrator is configured to generate and deliver oxygen enriched air to the patient according to a selected dosage. The oxygen concentrator senses and collects physiological data of the patient and collects operational data during the generation and delivery of oxygen enriched air. The oxygen concentrator adjusts the dosage of oxygen enriched air based on the sensed physiological data. The oxygen concentrator transmits operational data and the physiological data to a health data analysis engine. The health data analysis engine collects the data transmitted by the oxygen concentrator. The health analysis engine detects a triggering event based on the collected data and determines an action to resolve the detected triggering event.

Methods and systems for capturing capnography data during high-flow oxygen therapy (HFOT) are disclosed. An example method includes delivering HFOT by delivering breathing gases at an operational flow rate and an operational oxygen concentration level; initiating a temporary flow-reduction function for a set duration, wherein breathing gases are delivered at a temporary flow rate for the set duration, the temporary flow rate being less than the operational flow rate; capturing capnography data for exhaled air during the set duration; and upon expiration of the set duration, resuming HFOT delivery.

Methods and systems for capturing capnography data during high-flow oxygen therapy (HFOT) are disclosed. An example method includes delivering HFOT by delivering breathing gases at an operational flow rate and an operational oxygen concentration level; initiating a temporary flow-reduction function for a set duration, wherein breathing gases are delivered at a temporary flow rate for the set duration, the temporary flow rate being less than the operational flow rate; capturing capnography data for exhaled air during the set duration; and upon expiration of the set duration, resuming HFOT delivery.