Interfaces for positive pressure therapy having a mask assembly, a headgear assembly and a connection port assembly are disclosed herein. The connection port assembly has a ball joint connection with the mask assembly and includes a quick release button for easily disconnecting the gases source conduit from the mask assembly. The mask assembly may include a bias flow vent that is formed separately and attached to the mask assembly. The headgear assembly encircles the rear region of the user’s head and may include at least some portions that are substantially non-stretchable.

A system for accessing a patient's uterine cavity and detecting perforations in the uterus includes an elongated probe having a flow channel extending to a terminal outlet in a distal region of the probe. A fluid source is coupled to the flow channel, and a seal on the probe is positionable in an endocervical canal. The probe may be trans-cervical inserted into the uterine cavity, and a fluid may be introduced through the channel to flow outwardly from the terminal outlet into the uterine cavity. A parameter of said fluid flow is monitored to detect a perforation in the uterus.

A method includes receiving a pressure signal from a pressure sensor and/or a flow signal from a flow sensor and receiving signals from one or more sensors that measure different physiological parameters from the pressure sensor and the flow sensor. The method includes detecting the onset of the spontaneous breath by the patient based on the pressure signal and/or the flow signal and synchronizing providing breathing support to the patient with the onset of the spontaneous breath detected utilizing the pressure signal and/or the flow signal. The method includes calibrating parameters and thresholds to be utilized in detecting the onset of the spontaneous breath based on the signals. The method includes after calibration, switching to: detecting the onset of the spontaneous breath by the patient based on the signals and synchronizing providing breathing support to the patient with the onset of the spontaneous breath detected utilizing the signals.

A method includes receiving a pressure signal from a pressure sensor and/or a flow signal from a flow sensor and receiving signals from one or more sensors that measure different physiological parameters from the pressure sensor and the flow sensor. The method includes detecting the onset of the spontaneous breath by the patient based on the pressure signal and/or the flow signal and synchronizing providing breathing support to the patient with the onset of the spontaneous breath detected utilizing the pressure signal and/or the flow signal. The method includes calibrating parameters and thresholds to be utilized in detecting the onset of the spontaneous breath based on the signals. The method includes after calibration, switching to: detecting the onset of the spontaneous breath by the patient based on the signals and synchronizing providing breathing support to the patient with the onset of the spontaneous breath detected utilizing the signals.

A patient interface for treating sleep disorder breathing includes a headgear tube that provides support for the seal forming structure. The headgear tube includes a patient-contacting portion and a non-patient contacting portion that are joined along seams to form a gas passageway. The headgear tube may comprise a textile material and/or a foam material. Portions of the headgear tube may be imparted with greater rigidity than other portions.

A patient interface for treating sleep disorder breathing includes a headgear tube that provides support for the seal forming structure. The headgear tube includes a patient-contacting portion and a non-patient contacting portion that are joined along seams to form a gas passageway. The headgear tube may comprise a textile material and/or a foam material. Portions of the headgear tube may be imparted with greater rigidity than other portions.

The present invention is directed to systems, devices and methods for trans-septally delivering carbon dioxide through a minimally invasive catheter to create a gaseous pocket or emphysema between the posterior wall of the left atrium and the esophagus during cardiac ablation of the left atrium. This pocket of gas expanded tissue serves to thermally insulate and separate the esophagus from the left atrium during ablation to prevent the formation of an atrial-esophageal fistula. The system comprises a control system to precisely deliver the gas to a desired location through a needle-based catheter assembly.

The present invention is directed to systems, devices and methods for trans-septally delivering carbon dioxide through a minimally invasive catheter to create a gaseous pocket or emphysema between the posterior wall of the left atrium and the esophagus during cardiac ablation of the left atrium. This pocket of gas expanded tissue serves to thermally insulate and separate the esophagus from the left atrium during ablation to prevent the formation of an atrial-esophageal fistula. The system comprises a control system to precisely deliver the gas to a desired location through a needle-based catheter assembly.

An oxygenator apparatus for use in an extracorporeal circuit. The apparatus includes a housing and a membrane assembly disposed within the housing. The membrane assembly includes a first plurality of gas exchange elements disposed in a first zone and a second plurality of gas exchange elements disposed in a second zone. The second zone is arranged concentrically around the first zone. The first and second plurality of gas exchange elements are fluidly open along a body and fluidly separated along a distal end. The first zone is configured to be fluidly coupled to an oxygen source and the second zone is configured to be fluidly coupled to a negative pressure source. A blood flow path includes a generally radial flow through the first zone to add oxygen to the blood and the second zone to separate gaseous micro emboli from the blood through the plurality of gas exchange elements.

This disclosure provides a mask assembly for respiratory therapy, comprising: a vent for exhausting gas flow from an interior of the mask assembly, the vent comprising at least one vent hole; and a diffuser material defining a diffusing area sufficient to cover the vent hole and having a periphery. A region of the diffusing area of the diffuser material includes a localised joint region in which multiple fibres of the diffuser material are bonded or interlocked together. The location of the localised joint region is offset from the vent hole. Further embodiments are disclosed in which the shape of the diffusing material matches the shape of a vent hole array, or has other properties related to the vent hole array or the shape or other features of the vent.