Systems and methods for delivering a gas, such as nitric oxide, are provided. In some embodiments, systems and methods are provided for delivering a gas, such as nitric oxide, in the form of nanobubbles and/or a dissolved gas using a liquid medium.

A patient interface may include a plenum chamber pressurisable to a therapeutic pressure; a seal-forming structure constructed and arranged to form a seal with a region of the patient's face; a positioning and stabilising structure to provide an elastic force to hold the seal-forming structure on the patient's head, the positioning and stabilising structure may include a tie; a vent structure; a decoupling structure configured to provide a fluid connection between the plenum chamber and an air circuit for the flow of air at the therapeutic pressure for breathing by the patient; and a frame having at least one tie attachment structure to receive the tie, wherein the frame is configured to be resiliently movable in any direction having at least one of a component parallel to the patient's sagittal plane, a component parallel to the patient's coronal plane, a component parallel to the patient's Frankfort horizontal plane.

A patient interface may include a plenum chamber pressurisable to a therapeutic pressure; a seal-forming structure constructed and arranged to form a seal with a region of the patient's face; a positioning and stabilising structure to provide an elastic force to hold the seal-forming structure on the patient's head, the positioning and stabilising structure may include a tie; a vent structure; a decoupling structure configured to provide a fluid connection between the plenum chamber and an air circuit for the flow of air at the therapeutic pressure for breathing by the patient; and a frame having at least one tie attachment structure to receive the tie, wherein the frame is configured to be resiliently movable in any direction having at least one of a component parallel to the patient's sagittal plane, a component parallel to the patient's coronal plane, a component parallel to the patient's Frankfort horizontal plane.

A portable ventilator module is provided and includes a data module capable of artificial intelligence (AI) and/or machine learning (ML). The ventilator module is detachably attachable to an anaesthesia module to enable a single device to collect data from a patient in critical care and theatre environments. Also provided is a system for the unbroken acquisition of data from the entire patient stay in critical care, emergency areas and theatres in a single device by including a data module capable of AI or ML within a portable ventilator module, wherein the portable ventilator module can provide life-sustaining ventilation support to a patient in critical care and wherein the portable ventilator can dock with an anaesthesia module to provide anaesthesia during operations in theatre so that a machine change from an ICU ventilator to a separate anaesthesia machine and back again is not required, thereby avoiding data loss.

A method includes receiving data associated with a user during a sleep session. The received data is analyzed to determine, for a selected timeframe during the sleep session, whether the user is breathing through nostrils of the user. Based at least in part on a result of the analysis, a mask recommendation is communicated.

A method includes receiving data associated with a user during a sleep session. The received data is analyzed to determine, for a selected timeframe during the sleep session, whether the user is breathing through nostrils of the user. Based at least in part on a result of the analysis, a mask recommendation is communicated.

A patient interface for delivery of gas to a patient comprises at least one inspiratory element for directing a flow of gas to a patient airway, at least one expiratory element comprising an expiratory gas flow path for directing expiratory gases from the patient; and at least one gas permeable body in the expiratory gas flow path. Each inspiratory element comprises at least one inspiratory lumen through which said flow of gas is directed. The gas permeable body is configured such that expiratory gases in the expiratory gas flow path are directed through the gas permeable body before exiting the patient interface.

A patient interface for delivery of gas to a patient comprises at least one inspiratory element for directing a flow of gas to a patient airway, at least one expiratory element comprising an expiratory gas flow path for directing expiratory gases from the patient; and at least one gas permeable body in the expiratory gas flow path. Each inspiratory element comprises at least one inspiratory lumen through which said flow of gas is directed. The gas permeable body is configured such that expiratory gases in the expiratory gas flow path are directed through the gas permeable body before exiting the patient interface.

A face shield, patient interface and methods of use thereof are described for improved respiratory therapy of patients. In particular, a face shield is disclosed that acts as a seal when used with a patient interface. The face shield may be manufactured from a low melt temperature hard thermoplastic material. The face shield may be formed initially formed to match the general contours of the face, but not customised to a specific user's face. The face shield may be crosslinked to provide shape memory to the seal and to improve its handling properties and is configured to be thermoformed to a user's face. The face shield may be customised to the patient's facial features to a second customised shape.

A face shield, patient interface and methods of use thereof are described for improved respiratory therapy of patients. In particular, a face shield is disclosed that acts as a seal when used with a patient interface. The face shield may be manufactured from a low melt temperature hard thermoplastic material. The face shield may be formed initially formed to match the general contours of the face, but not customised to a specific user's face. The face shield may be crosslinked to provide shape memory to the seal and to improve its handling properties and is configured to be thermoformed to a user's face. The face shield may be customised to the patient's facial features to a second customised shape.