A nebulizer for producing an inhalable mist of droplets, comprising at least an aerosol generator, a housing having a liquid reservoir and control electronics, the aerosol generator consisting at least of a membrane, a piezo element and a substrate plate, and the control electronics comprising at least an RF generator, a controller, memory and switching elements, and an inductor. The aerosol generator forms a resonant circuit together with the inductor and the control electronics are configured to at least partly excite the aerosol generator to vibrate. The aerosol generator is configured such that aerosol droplets are producible by vibrations and the RF generator is configured to vary the amount of aerosol produced.

The invention relates to an ultrasonic mist inhaler (100), comprising: —a mouthpiece (1) for inhaling the mist, —a liquid reservoir structure (2) comprising a liquid chamber (21) adapted to receive liquid to be atomized, —a sonication chamber (22) in fluid communication with the liquid chamber (21), wherein at least part of the liquid reservoir structure (2) and the mouthpiece (1) form the sonication chamber (22).

A system includes a converter configured to electrically couple to a power source and to a heating element of a vaporizer atomizer. The converter can be further configured to receive a first voltage from the power source and provide a second voltage to the heating element. The converter can be a direct-current to direct-current converter. A power monitor configured to electrically couple to the heating element, measure a current through the heating element, measure a voltage over the heating element, calculate a power and/or resistance, and output a control signal to the converter. The converter can be configured to be controlled by the control signal to vary the second voltage to maintain a target power or a target temperature over the heating element. Related apparatus, systems, techniques and articles are also described.

A system includes a converter configured to electrically couple to a power source and to a heating element of a vaporizer atomizer. The converter can be further configured to receive a first voltage from the power source and provide a second voltage to the heating element. The converter can be a direct-current to direct-current converter. A power monitor configured to electrically couple to the heating element, measure a current through the heating element, measure a voltage over the heating element, calculate a power and/or resistance, and output a control signal to the converter. The converter can be configured to be controlled by the control signal to vary the second voltage to maintain a target power or a target temperature over the heating element. Related apparatus, systems, techniques and articles are also described.

The disclosure relates to an electronic atomizing device and an atomizer and a liquid injection structure thereof. The liquid injection structure includes an outer pipe provided with an exhaust port and a liquid injection assembly including a sleeve pipe disposed in the outer pipe and a liquid injection pipe disposed in the sleeve pipe. The liquid injection pipe is provided with a liquid injection port, and is axially movable relative to the sleeve pipe between a first position where the sleeve pipe seals the liquid injection port and a second position where the seal of the liquid injection port by the sleeve pipe is released. The sleeve pipe is axially movable relative to the outer pipe between a third position where the sleeve pipe seals the exhaust port and a fourth position where the seal of the exhaust port by the sleeve pipe is released.

A combination stylet device for use in guiding an endotracheal tube during an intubation procedure includes an elongated hollow sleeve having a fitting at one end configured for mating with a syringe and a nozzle at the second end for generating a fine spray of a liquid forward from the second end. An elongated bendable guiding stylet is disposed coaxially within the sleeve to define a channel through which pressurized liquid is conducted from the fitting to the nozzle. The sleeve is inserted into the endotracheal tube during intubation to guide the insertion and to allow for administration a medication from the end of the endotracheal tube.

A dry burning detection method, applied to a vaporizer, includes: obtaining vaporization parameters of a vaporization piece in real time, and calculating a variance between the vaporization parameters and a sample mean, the sample mean being a value representing a vaporization parameter level of a stable vaporization stage of the vaporizer; and determining that the vaporization piece is dry-burned if the variance is greater than a preset variance value corresponding to the vaporization parameter, the preset variance value being used for distinguishing a vaporization parameter fluctuation caused by vaporization dry burning and a vaporization parameter fluctuation caused by non-vaporization dry burning.

A mist inhaler device (200) for generating a mist for inhalation by a user. The device comprises a mist generator device (201) and a driver device (202). The driver device (202) is configured to drive the mist generator device (201) at an optimum frequency to maximise the efficiency of mist generation by the mist generator device (201).

Some embodiments provided herein relate to methods, systems and kits for providing consistent intracoronary administration of a biologic to subjects having diverse coronary anatomies. In some embodiments, the biologic is an adeno-associated virus serotype 1 (AAV1) vector encoding sarcoplasmic/endoplasmic reticulum ATPase 2a (SERCA2a) protein.

An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.