A reusable apparatus, such as a medical instrument or tool, is decontaminated by applying pressure waves with direct contact of the pressure wave applicator to the reusable apparatus in an open bath in a sufficient dosage to remove contamination but without adversely affecting the ability to reuse the apparatus.

A reusable apparatus, such as a medical instrument or tool, is decontaminated by applying pressure waves with direct contact of the pressure wave applicator to the reusable apparatus in an open bath in a sufficient dosage to remove contamination but without adversely affecting the ability to reuse the apparatus.

Flow capture device and method for removing cells from blood The current invention discloses a blood treating and/or purifying device for removing circulating pathogens, preferably pathogenic cells, more preferably circulating tumor cells from the blood of a patient, a method of producing such a device and method to treat cancer and other diseases caused by virus infection, bacterial infection and parasites infection as well as autoimmune disorders. The described method is an extracorporeal medical therapy, thus can be done also in a hemodialysis system. The current invention also describes a device and an in-situ production method of preparing the device to remove CTC and other pathogens i.e. virus, bacteria or parasites from the bloodstream.

Embodiments of the present disclosure provide systems and devices for delivering gaseous Nitric Oxide (gNO) under therapeutic parameters to reduce infection in a subject. Certain embodiments include devices and systems for delivering pressurized gNO to reduce bioburden and promote healing in the wounds of subjects having various disease conditions, including skin and soft tissue infections (SSTIs) and osteomyelitis. In some embodiments, the present disclosure provides portable wound healing devices for delivering pressurized gNO to the site of a wound to treat various disease conditions in a subject. Other embodiments relate to systems and devices for delivering and for monitoring gaseous Nitric Oxide (gNO) under therapeutic parameters of use to treat a subject. In certain embodiment, the devices include a subject interface unit comprising sensors for detecting gNO pressure and/or gNO flow.

A breathing apparatus may include a heater configured to kill harmful organisms in air. The apparatus may include a vest, including a heating chamber disposed on the vest and a cooling chamber disposed on the vest. The heating chamber may include a heat source, and the heat source may heat air disposed within the heating chamber to a predetermined temperature. The heating chamber and the cooling chamber may be in fluid communication. The apparatus may include a breathing tube, including a first end and a second end. The first end may connect to the cooling chamber. The apparatus may include a breathing mask. The second end of the breathing tube may connect to the breathing mask. The cooling chamber and the breathing mask may be in fluid communication via the breathing tube.

A fluid filtration system comprising a cross-flow filter is arranged to permit a first pump to recirculate part of the retentate of the filter to the inlet of the cross-flow filter and a second pump to return part of the permeate to the inlet of the cross-flow filter. A third pump is configured supply source fluid to the inlet of the filter. The flow path between the second pump and the cross-flow filter inlet may include an adsorption filter that may selectively remove contaminants, toxins, or pathogens in the permeate. A controller may control the first, second and third pumps to provide predetermined flow ratios among the fluid flow paths of the system in order to achieve a desired filtration level. This system may be applicable to the removal of harmful substances from blood, by first separating the plasma from the blood and then removing harmful substances from the plasma.

The invention disclosed herein concerns screening and early detection of a variety of disease conditions in seemingly healthy subjects, enabling early intervention and treatment.

A reusable respirator including a mask adapted for covering and conforming to the face around the nose and a mouth of a user, a strap configured to secure the mask to a face of the user, and a filter component. All components of the respirator are capable of being cleaned, disinfected and sterilized at temperatures in excess of 50° C. An outer surface of the mask is substantially smooth and wettable for easily disinfecting and is shaped with a pair of outer shield portions for housing particulate air filters. The outer shield portions each include a closeable vent through the outer surface that is adapted to provide a user seal check and direct air flow through the outer surface for filtering by the respective particulate air filter, which is adapted to filter at least 95% of airborne particles.

Described are methods for providing a pulsed dose of a gaseous drug over a portion of total inspiratory time, where the dose of the gaseous drug is delivered at a concentration of nL of gaseous drug per mL tidal volume.

Devices, systems, and methods for protecting medical personnel during medical procedures are disclosed herein. The present technology may comprise, for example, a flexible barrier configured to be positioned over all or a portion of the patient's head during the procedure. The barrier may comprise a first side configured to face towards the patient during the procedure and a second side configured to face towards a healthcare worker during the procedure. The barrier can include an access region configured to be positioned at or near a mouth of the patient when the barrier is positioned on the patient during the procedure. The access region can be configured to provide passage of a medical device through the barrier and into an oral cavity of the patient while maintaining a physical barrier around the medical device.