A fluid dispenser device comprising: a body (100) that is provided with a dispenser orifice (110); a reservoir (1) containing fluid and a propellant gas; and a metering valve (20) that is assembled on said reservoir (1); said reservoir (11) being movable in said body (100) so as to actuate the metering valve (20) and dispense a dose of fluid through said dispenser orifice (110), said metering valve (20) including a valve member (30) that slides in said metering valve (20) during actuation; said device further comprising at least one sealing element (40, 41, 42) so as to form a leaktight seal, at least one sealing element (40, 41, 42) of said device comprising Cyclic Block Copolymer (CBC).

Provided is a syringe gasket including a first member, and a second member connected to the first member and coupled to a plunger rod of a syringe. The first member includes a top face contacting with the liquid, and a first side circumferential face that faces an inner circumferential face of a barrel of the syringe. The first side circumferential face has, at an end portion thereof close to the second member, a ring-like trimmed face. An inert film is laminated on the top face and the portion of the first side circumferential face other than the ring-like trimmed face. The second member includes a second side circumferential face that faces the inner circumferential face of the barrel, and a ring-like protruding portion that projects outward in the radial direction from the second side circumferential face. The ring-like protruding portion at least partially covers the ring-like trimmed face.

A blood pump includes an impeller; a drive shaft coupled to the impeller and configured to rotate with the impeller; and a rotor coupled to the drive shaft and configured to rotate with the drive shaft. The rotor includes a driven magnet having an outer surface. A corrosion-resistant coating may be disposed on the outer surface of the driven magnet. A stator is disposed adjacent the rotor and configured to drive the rotor, causing the rotor to rotate; and a motor is configured to drive the stator. A protection assembly may be disposed adjacent the stator and configured to receive an end of the drive shaft, and may include a protection assembly housing enclosing a protective fluid chamber, the protective fluid chamber including the driven magnet and at least a portion of a bearing configured to engage the end of the drive shaft.

There is provided a rotatable impeller assembly for pumping caustic fluid byproducts in a medical device. The assembly comprises a rotor having a rotor cup, and an impeller having a rotor contacting surface and impeller blades. The assembly further comprises a magnetic ring seated within the cup. The magnetic ring comprises a first contact surface that is configured to mate with an inner surface of the cup, and a second contact surface that is configured to mate with the rotor contacting surface of the impeller. In such an arrangement, the magnetic ring is locked in position by the rotor cup and the impeller, thereby preventing any independent rotation of the magnetic ring relative to the rotor and the impeller while automatically balancing the rotor. Further, the rotor contacting surface of the impeller is attached to the cup to hermetically seal the magnetic ring within the impeller assembly.

A nano-scale device and method of manufacturing and use. The nano-scale device may be used in-vivo and may comprise a fluid path with an inlet microchannel, an outlet microchannel, and a nanochannel. The fluid path comprises a bio-robust material. In certain embodiments, the bio-robust material may be coated over a material that is not bio-robust.

A heating apparatus includes a heating element which converts electrical power to heat energy, a heatable element having a first surface and a second surface, and a dielectric laminate layer between the heating element and the first surface of the heatable element, wherein the dielectric laminate layer is thermally conductive to transfer heat energy from the heating element to the heatable element, and wherein the second surface of the heatable element is configured heat a liquid in a container.

A fluid dispenser device comprising: a body (100) that is provided with a dispenser orifice (110); a reservoir (1) containing fluid and a propellant gas; and a metering valve (20) that is assembled on said reservoir (1); said reservoir (11) being movable in said body (100) so as to actuate the metering valve (20) and dispense a dose of fluid through said dispenser orifice (110), said metering valve (20) including a valve member (30) that slides in said metering valve (20) during actuation; said device further comprising at least one sealing element (40, 41, 42) so as to form a leaktight seal, at least one sealing element (40, 41, 42) of said device comprising Cyclic Block Copolymer (CBC).

A heating apparatus includes a heating element which converts electrical power to heat energy, a heatable element having a first surface and a second surface, and a dielectric laminate layer between the heating element and the first surface of the heatable element, wherein the dielectric laminate layer is thermally conductive to transfer heat energy from the heating element to the heatable element, and wherein the second surface of the heatable element is configured heat a liquid in a container.

A syringe is to be obtained by using PTFE for a gasket main body that makes a direct contact with an injection solution and using a slidable silicone rubber at a portion that does not make contact with the injection solution. A syringe A includes a syringe barrel 1, a gasket 10 press-fitted within the syringe barrel 1, and a plunger rod 5 mounted in the gasket 10. In the gasket 10, a concaved groove 18 is formed over the whole circumference of a slide-contact surface 11 of a main body portion 26 that is formed of a rigid plastic having a drug solution-resistant property against a drug solution 30 to be loaded in the syringe barrel 1 and that is configured to slidingly contact an inner circumferential surface 2 of the syringe barrel 1. In a slide-contact ring 19 that is to be fitted in the concaved groove 18 and that is configured to slidingly contact the syringe barrel inner circumference surface 2, a silicone oil and a spherical ultrahigh molecular weight fine powder are added to a silicone rubber base material 19c.

An extracorporeal blood heating and cooling system that is connectable to an oxygenator of a cardiopulmonary bypass system, the heating and cooling system comprising: a heater-cooler unit; a coolant flow circuit that is configured to pass coolant through the heater-cooler unit and the oxygenator; and a cardioplegia coolant circuit that is configured to pass coolant through the heater-cooler unit and a cardioplegia heat exchanger; wherein when the heating and cooling system is in a purging mode, the coolant flow circuit and the cardioplegia coolant circuit contain temperature-controlled coolant having a trisodium phosphate concentration of about 1-35 millimole/liter; wherein when the heating and cooling system is in a coolant mode, the coolant flow circuit and the cardioplegia coolant circuit contain temperature-controlled coolant having a trisodium phosphate concentration of about 1-10 millimole/liter; and wherein when the heating and cooling system is in the coolant mode or the purging mode, a first and second plurality of coolant conduits within the oxygenator and the cardioplegia heat exchanger are capable of maintaining a trisodium phosphate concentration ratio across the wall of such coolant conduits of at least 100:1, from the interior to the exterior of each coolant conduit. Methods of purging and operating such extracorporeal blood heating and cooling systems are also disclosed.