Method for targeted application of active agents to a target surface including: creating a digital geometric representation of the target surface; providing an array of applicators; selecting an applicator from the array of applicators based on the target surface; disposing the active agent on the applicator surface of the applicator; disposing the applicator on the target surface so that the active agent is in contact with the target surface; and removing the applicator from the target surface while leaving at least some of the active agent in contact with the target surface.

It is well understood in the medical industry that medical disorders can manifest as serious problems for the affected subjects, their families, and society. Today, psychiatrists, neurologists and other physicians treat these disorders with a variety of medications, many of which have significant negative side effects. The teachings provided herein are directed to a novel system and methods for treating certain neurological, psychological, psychiatric and medical disorders by delivering a “magnetic stimulation” to a subject's neural and perineural system using either a static or electromagnetic field to generate a modulated variable power multi-spectral magnetic stimulation on three axis; the modulated stimulation using methods that have predictable, controlled, modifiable, and repeatable characteristics.

An iontophoresis system includes a preloaded reservoir containing one or more doses of a therapeutic agent. As a result, the therapeutic agent does not have to be loaded into the reservoir prior to use. In such a system, the preloaded reservoir is generally disposable. Various components of the iontophoresis system can be combined with the reservoir in a disposable cartridge that is selectively connectable to other, reusable components of the iontophoresis system. In addition, the entire iontophoresis system can be formed from one or more disposable, one-time-use modules.

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a proximal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distal ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides.

A system includes a nose-to-brain medication delivery device including a medication dispersion device and a magnetic field generator. The generator, when in use, generates a magnetic field of sufficient strength and direction to reposition an ionized and/or magnetized medication to a selected drug delivery site on the brain following initial delivery of the medication from the medication delivery device to the brain cavity via the nose while bypassing the blood-brain barrier.

A stimulation arrangement comprising an induction device having a field generator configured to generate a spatial field, a sensor unit, and a control unit in communication with the induction device and the sensor unit. The field generator of the induction device is configured to be positioned at a human or animal patient such that an inspiration muscular structure of the patient is stimulatable by the spatial field, the sensor unit is configured to be positioned at the human or animal patient to sense a feedback of the respiratory system or the patient, and the control unit is configured to control the induction device to generate the spatial field and to receive a feedback signal from the sensor unit. The control unit is configured to evaluate the feedback signal received from the sensor unit, and to activate the field generator of the induction device when the feedback signal is indicative of an abnormality.

The present invention includes an apparatus for transdermal treatments comprising: an openable enclosure for a subject in communication with three or more sources of treatment modalities selected from: a source of ozone; a source of steam, a source of CO.sub.2/Carbonic Acid; a source of Far Infrared; and a source of pulsed electromagnetic fields (PEMF), wherein each of the three or more sources is in communication with an interior of the openable enclosure to treat the subject transdermally.

The present invention includes an apparatus for transdermal treatments comprising: an openable enclosure for a subject in communication with three or more sources of treatment modalities selected from: a source of ozone; a source of steam, a source of CO.sub.2/Carbonic Acid; a source of Far Infrared; and a source of pulsed electromagnetic fields (PEMF), wherein each of the three or more sources is in communication with an interior of the openable enclosure to treat the subject transdermally.

A fully implanted automatic disorder response system is devised to act as a backup “immune” system, automatically detecting and dispensing an enzyme, for example, deficient due to an inborn error of metabolism. In response to a disease, the agent released is one or more drugs. By directly pipeline-targeting agents through a closed system of drug reservoirs, fluid and electrical lines, and leak-free, durable, and safe tissue connectors to the site of disease, the system achieves a level of efficiency critically superior to the systemic dispersal of an agent into the circulation, fundamentally liberalizing the use of drugs. In comorbid disease, each morbidity is assigned to an arm or channel in a hierarchical control system. Beginning with symptomatic indicia sensors, data is analyzed and passed up through successively higher-level nodes that generate a cross-morbidity view passed up to an implanted microprocessor which effectuates a release of drugs calculated to optimize homeostasis.

An electro-magnetic induction device for activating a target tissue in a body via its muscular or neural system includes an electro-magnetic field generator with a coil design configured to generate an electro-magnetic field, a mounting arrangement holding the coil design at the body, a sensor member configured to detect an activation of a target tissue, an electro-magnetic field adjustment mechanism configured to automatically adjust the position and a field strength of the electro-magnetic field, and a calibration unit in communication with the sensor member and the electro-magnetic field adjustment mechanism. The calibration unit is configured to control the electro-magnetic field adjustment mechanism to automatically vary the position and the field strength of the electro-magnetic field, to receive an activation feedback signal from the sensor, and to control the electro-magnetic field adjustment mechanism to automatically stop variation of the position of the electro-magnetic field generated by the coil design.