An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.

A method of stimulating human blood external of a patient donor has the steps of activating an acoustic shock wave or pressure pulse generator to emit acoustic shock waves or pressure pulses directed to impinge the blood, subjecting the blood to the acoustic shock waves or pressure pulses to form stimulated blood cells and transfusing the stimulated blood cells into the patient donor. The patient donor is infected with a virus and the blood exhibits at least traces of the virus. The emitted acoustic shock waves or pressure pulses stimulating the stimulated blood cells fragment the virus in the blood. The fragmented virus in the blood transfused back into the patient donor triggers a defensive immune response to kill the virus. The emitted acoustic shock waves or pressure pulses are preferably of a low energy. The emitted shock waves or pressure pulses stimulate the blood cells and fragment the virus in the absence of cell damaging cavitation due to an elasticity in the blood cells and a lack of elasticity in the virus. The blood is not filtered. The blood can be oxygenated via Extracorporeal membrane oxygenation (ECMO) after being stimulated.

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

An electro-magnetic induction device for activating a target tissue in a body via its muscular or neural system includes an electro-magnetic field generator with a coil design configured to generate an electro-magnetic field, a mounting arrangement holding the coil design at the body, a sensor member configured to detect an activation of a target tissue, an electro-magnetic field adjustment mechanism configured to automatically adjust the position and a field strength of the electro-magnetic field, and a calibration unit in communication with the sensor member and the electro-magnetic field adjustment mechanism. The calibration unit is configured to control the electro-magnetic field adjustment mechanism to automatically vary the position and the field strength of the electro-magnetic field, to receive an activation feedback signal from the sensor, and to control the electro-magnetic field adjustment mechanism to automatically stop variation of the position of the electro-magnetic field generated by the coil design.

One embodiment is directed to a non-contact, medical ultrasound therapy system for generating and controlling low frequency ultrasound for the delivery of fluids containing biologic or cellular materials. The ultrasound therapy system includes a treatment wand including an ultrasonic transducer, a generator unit, and a cable coupling the treatment wand to the generator unit. The generator unit generates electric power output to drive the ultrasonic transducer and includes a digital frequency generator.

The invention provides compositions, kits and methods for depositing a composition comprising a plurality of magnetic particles, to a target site of a subject by delivering the composition via controlled inhalation to a region of the subject's respiratory tract and applying a magnetic field to a target site within the region of the subject's respiratory tract to capture the particles in said target site.

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to achieve pain relief. The devices are designed such that the microstructures are able to grasp and secure to the skin. The devices may consist of microstructures in arrays that are attached to a backing to enable the devices to adhere to the skin. Also provided are wound closure systems that comprise one or more microstructure devices along with other components, such as protective covers and therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the devices. Methods described herein provide for treatment of pain.

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.