A fluid handling cassette, such as that useable with an automated peritoneal dialysis (APD) cycler device or other infusion apparatus, may include a generally planar body having at least one pump chamber formed as a depression in a first side of the body and a plurality of flowpaths for a fluid that includes a channel. A patient line port may be arranged for connection to a patient line and be in fluid communication with the at least one pump chamber via at least a first one of said flowpaths, and an optional membrane may be attached to the first side of the body over the at least one pump chamber. In one embodiment, the membrane may have a pump chamber portion with an unstressed shape that generally conforms to the depression of the at least one pump chamber in the body and is arranged to be movable for movement of the fluid in a useable space of the at least one pump chamber. One or more spacers may be provided in the at least one pump chamber to prevent the membrane from contacting an inner wall of the at least one pump chamber. The patient line, a drain line, and/or a heater bag line may be positioned to be separately occludable in relation to one or more solution lines that are connectable to the cassette.

The present invention provides a controller for an inhalation device, comprising: a sensor configured to detect an atomization request of an aerosol source; and a processor configured to perform energization control of a heater, which is used to heat the aerosol source, in accordance with the atomization request detected by the sensor, wherein the processor determines whether each of a first constraint condition, a second constraint condition, and a third constraint condition for the energization control is met, and restricts, in a case where at least one of the first constraint condition, the second constraint condition, and the third constraint condition is met, energization to the heater even if the atomization request is detected by the sensor.

Components for a medical infusion fluid handling system, such as an APD system, in which one or more lines (such as solution lines), spikes or other connection ports may be automatically capped and/or de-capped. This feature may provide advantages, such as a reduced likelihood of contamination since no human interaction is required to de-cap and connect the lines, spikes or other connections. For example, a fluid handling cassette may include one or more caps that cover a corresponding spike and include a raised and/or recessed feature to assist in removal of the cap from the cassette. A solution line cap may include a hole and recess, groove or other feature to engage with a spike cap and enable removal of the cap.

This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference.

A control body is coupled or coupleable with a cartridge that is equipped with a heating element and contains an aerosol precursor composition, the control body and cartridge forming an aerosol delivery device. The control body includes a control to control the heating element to activate and vaporize components of the aerosol precursor composition. The proximity sensor detects a presence of an object nearby the control body without requiring any physical contact with the object. And the proximity sensor or control component controls operation of at least one functional element of the aerosol delivery device in response to the presence of the object so detected. In another aspect, a cartridge may include a proximity sensor to detect a level of the aerosol precursor composition, and operation of functional element(s) may be controlled in response to the level of the aerosol precursor composition so detected.

Devices, systems and methods for controlling a patient's body temperature by endovascular heat exchange and/or surface heat exchange.

A medical infusion fluid handling system, such as an automated peritoneal dialysis system, may be arranged to de-cap and connect one or more lines (such as solution lines) with one or more spikes or other connection ports on a fluid handling cassette. This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines and the one or more spikes. For example, the automated peritoneal dialysis system may include a carriage arranged to receive the one or more lines each having a connector end and a cap. The carriage may move along a first direction so as to move the connector ends of the one or more lines along the first direction, and a cap stripper may be arranged to engage with the caps on the solution lines on the carriage. The cap stripper may move in a second direction transverse to the first direction, as well as to move with the carriage along the first direction.

An electronic aerosol safety system including at least one aerosol safety sensor for measuring or sensing parameters of a target in an aerosol stream and a warning device in communication with the sensor, wherein the warning device can provide a user with safety and efficacy information. There is also provided a method of increasing the safety of an aerosol delivery device by attaching or integrating the electronic aerosol safety system into an aerosol delivery system, monitoring the aerosol produced by the aerosol delivery device by detecting preset parameters using the electronic aerosol safety system and triggering a notification to a user of the aerosol delivery device, wherein the triggering occurs upon detection of a deviation from the preset parameters.

A medical treatment system, such as a peritoneal dialysis system, may include a control and other features to enhance patient comfort and ease of use. For example, a cycler device may include a heater bag receiving section and a lid mounted to cover and uncover the heater bag receiving section, potentially enabling faster heating of a dialysate. A user interface may be moveable to be received into the receiving section and covered by the lid, if desired. The system may detect anomalous conditions, such as tilting of a housing of the system, and automatically recover without terminating a treatment. The system may include noise reduction features, such as porting pneumatic outputs to a common chamber, and others. The system may also automatically detect any one of several different solution lines connected to the system, and control operation accordingly, e.g., to mix solutions provided by two or more lines and form a needed dialysate solution. A cassette control surface may be arranged to have one or more ports that can detect a presence of a liquid, e.g., to identify if a cassette is leaking or has otherwise been compromised.

An indirect drain flush system incorporating hot water to facilitate the transport of kidney dialysis effluent to wastewater treatment facilities is provided. Heated water is discharged into a waste line through an air gap, and the heated water increases the molecular interchange of fatty substances in the dialysis effluent, decreasing the viscosity of those fatty substances and preventing them from coagulating or crystalizing on pipes and drains. An air admittance valve may prevent negative pressure from building up within the system.