According to certain embodiments, a surgical cassette for an ophthalmic surgical system comprises an irrigation conduit that is in fluid communication with a handpiece and carries fluid toward a surgical site. An aspiration conduit is in fluid communication with the handpiece and carries fluid away from the surgical site. An aspiration pump creates a vacuum pressure in the aspiration conduit to draw fluid through the aspiration conduit towards a drain reservoir. A reservoir couples with a pressure-vacuum source to manage the reservoir pressure. A valve is in fluid communication with the aspiration conduit and the reservoir, and provides one or more channels between the aspiration conduit and the reservoir. Each sensor detects a pressure associated with the surgical site. A computer controls the valve in response to the pressure detected by the one or more pressure sensors to mitigate a pressure or volume change.

A fluid processing system for controlling fluid flow comprises a cassette having a defined passageway on a first side. The first side includes flexible sheeting disposed over the passageway. The system comprises a durable processing device configured to engage the first side of the cassette, the durable processing device comprising a valve actuator configured to engage the flexible sheeting at a valve location along the passageway. The system comprises a first pump configured to draw fluid away from the valve location along the passageway. The first pump is disposed downstream of the valve location. The system comprises a second pump configured to pump fluid towards the valve location along the defined passageway. The second pump is disposed upstream of the valve location. The first and second pumps are configured to operate in concert and configured to provide pressure to prevent collapsing of the flexible sheeting against the passageway during operation.

A surgical irrigation cassette comprises a cassette housing, a portion of a pump, and fluid pathways. The housing defines a chamber therein and a first console connector including a first pneumatic connector port. The pump portion includes an intake side of the pump and an output side of the pump. The fluid pathways are disposed at least in part within the chamber. A first fluid pathway, in an installed position, connects the intake side of the pump with a supply fluid container. A second fluid pathway, in an installed position, connects the output side of the pump and a handpiece. A third fluid pathway, in an installed position, connects the handpiece and a waste container A fourth fluid pathway, in an installed position, connects the first console connector and the waste container.

A cassette usable with an infusion pump includes a monolithic cassette body and a segment of resiliently deformable tubing for conveying a flow of liquid. The monolithic cassette body has an integrally formed free-flow protection device including a fixed pinch element and a deflectable pinch arm having a movable pinch element. The pinch arm normally resides in a closed position wherein the pinch elements cooperate to deform the tubing segment to stop flow. The pinch arm is resiliently deflectable away from the closed position to an open position permitting flow. Deflection of the pinch arm away from the closed position spring biases the pinch arm for automatic return to the closed position. The pinch arm may be moved to the open position by operating a door of the pump when the cassette is loaded in the pump, and manually for priming when the cassette is not loaded in the pump.

A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.

A pump set for use with a pumping apparatus includes tubing for carrying a liquid. A valve mechanism is mounted to the tubing between an inlet section and a pump engagement section. The valve mechanism includes a first port connected to the inlet section of the tubing, a second port connected to the pump engagement section of the tubing, and a valve disposed between the first and second ports. The valve includes a stem rotatably mounted within a stem holder. The stem includes a flow passage extending through the stem and having an open V shape whereby a narrow open end of the flow passage communicates with the first port and a wide open end of the flow passage communicates with the second port to place the inlet section of the tubing in communication with the pump engagement section of the tubing.

A system for preventing cross-contamination in single-limb ventilators is described. In one embodiment, the system includes an airflow generator connected in-line to a humidifier, a first check valve and a patient interface by a gas flow circuit. A controller is electrically coupled to the airflow generator, and a cartridge is connected to the gas flow circuit between a first point downstream of the humidifier and a second point upstream of the patient interface. The cartridge includes a bacteria filter and the first check valve. A method for preventing cross-contamination in single-limb ventilators and a method for providing gaseous flow through a single-limb ventilator are also described.

A system for preventing cross-contamination in single-limb ventilators is described. In one embodiment, the system includes an airflow generator connected in-line to a humidifier, a first check valve and a patient interface by a gas flow circuit. A controller is electrically coupled to the airflow generator, and a cartridge is connected to the gas flow circuit between a first point downstream of the humidifier and a second point upstream of the patient interface. The cartridge includes a bacteria filter and the first check valve. A method for preventing cross-contamination in single-limb ventilators and a method for providing gaseous flow through a single-limb ventilator are also described.

A dry powder inhaler including replaceable cartridges containing a dry powder for local or systemic delivery through the pulmonary tract and lungs is disclosed. The inhalers are used with inhalable dry powders, including medicament formulations comprising active agents for local or systemic delivery and for the treatment of diseases such as, pulmonary hypertension, cardiovascular disease, anaphylaxis, diabetes, obesity, cancer, and other diseases, or symptoms associated with these and other diseases, such as nausea, vomiting, pain and inflammation.

A medical infusion fluid handling system, such as an automated peritoneal dialysis system, may be arranged to de-cap and connect one or more lines (such as solution lines) with one or more spikes or other connection ports on a fluid handling cassette. This feature may reduce a likelihood of contamination since no human interaction is required to de-cap and connect the one or more lines and the one or more spikes. For example, the automated peritoneal dialysis system may include a carriage arranged to receive the one or more lines each having a connector end and a cap. The carriage may move along a first direction so as to move the connector ends of the one or more lines along the first direction, and a cap stripper may be arranged to engage with the caps on the the one or more lines on the carriage. The cap stripper may move in a second direction transverse to the first direction, as well as to move with the carriage along the first direction.