Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

A fluid dispenser assembly having a nasal fluid dispenser device (1000) with a reservoir (30) and, a dispenser head (1) assembled on the reservoir (30); a remote mobile device (2000); and an orientation sensor (113) to obtain optimal orientation of the dispenser device (1000) when actuated. The sensor determines the three-dimensional orientation of the device, including the angle (α) of the device relative to said remote mobile device. A second sensor (121) is provided for detecting when the device (1000) is actuated by the user. The remote mobile device includes an accelerometer to determine its position in three-dimensional space, in particular the angle (β) of the remote mobile device (2000) relative to the vertical.

Methods, device, and systems for preparing peritoneal dialysis fluid and/or administering a peritoneal dialysis treatment are disclosed. In embodiments, peritoneal dialysis fluid is prepared at a point of use automatically using a daily sterile disposable fluid circuit and one or more long-term concentrate containers that are changed only after multiple days (e.g. weekly). The daily disposable may have concentrate containers that are initially empty and are filled from the long-term concentrate containers once per day at the beginning of a treatment.

Disclosed is a method and an auto-injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. The processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position with a plunger rod speed; determine plunger rod position; receive the resistance signal; and control the drive module to adjust movement of the plunger rod if the resistance signal is indicative of resistance against movement of the plunger rod above a high resistance threshold, wherein the high resistance threshold is based on the plunger rod position.

An electrically heated aerosol-generating device includes a storage portion configured to contain an aerosol-forming substrate and having a fluid permeable internal surface surrounding an open-ended passage extending through the cartridge. The device includes a housing having a cavity for receiving the cartridge, and a heater assembly positioned in the cavity. The heater assembly includes an elongate support member connected to the housing and arranged to extend into the open-ended passage of a cartridge inserted in the cavity. The heater assembly also includes a plurality of electric heaters fixed to and spaced along the length of the elongate support member.

A portable drain system having a subdermal drain and a container in fluid communication with the subdermal drain is disclosed. The subdermal drain is configured to drain fluid from a surgical site. The container provides a negative pressure to the subdermal drain. The container draws and receives the fluid. The container includes at least one sensor in which the at least one sensor is configured to detect at least one of fluid color, fluid volume in the container, and orientation of the container.

A wearable injector for automated delivery of biologic drugs that solves the problem of high volume and high viscosity drug administration by providing a device that can be worn by the patient through use of an adhesive patch to deliver the medication slowly over extended periods of time.

A system including a training drug delivery device and a user device is provided. The training drug delivery device includes a body, a cap, a delivery activation button, a controller, a memory, a wireless unit for communicating with the user device, a drive for simulating a haptic response of a drug delivery device, and at least one sensor for measuring attachment of the cap and depression of the delivery activation button. The user device includes a controller, a memory, and a wireless unit. The user device is configured to connect to the training drug delivery device, receive sensor measurements from the training drug delivery device, and provide, based at least partly on the received sensor measurements, the user with feedback on handling the training drug delivery device.

A plurality of flow rate values associated with pressurized air directed to an airway of a user of a respiratory therapy system is received. A plurality of pressure values associated with the pressurized air directed to the airway of the user is received. A first time associated with a first breath of the user and a second time associated with a second breath of the user are identified. The plurality of flow rate values is filtered based at least in part on the identified first time and the identified second time. The filtering produces a subset of the plurality of flow rate values. An intentional leak characteristic curve for the respiratory therapy system is determined using at least two of the subset of the plurality of flow rate values and the corresponding pressure values for the at least two of the subset of the plurality of flow rate values.

An injection monitoring device includes a syringe having a barrel configured to contain a medicament and a plunger configured to be displaced linearly into the interior of the barrel to dispense the medicament, a flange positioned between a proximal end and a distal end of the injection monitoring device and configured to be gripped during performance of the injection, and one or more force sensors positioned to detect data associated with an amount of force applied to the injection monitoring device during performance of an injection.