Adherence monitors are disclosed, incorporating cap removal sensors together with a determined time period in order to determine that a dose of medicament has been dispensed. In another form, cap removal data is combined with acoustic data to determine that a dose of medicament has been dispensed. Several specific structural arrangements are also disclosed.

The invention relates to an assistance device (10) for assisting in the use of an axially activated dispensing device (12) for dispensing a product contained in a tank (14), the dispensing being activated by the user following pressure exerted by the user on a bearing area (20) mounted so as to be able to move with respect to the tank (14) between a rest position and an activated dispensing position, the assistance device (10) comprising: means for connecting it to the dispensing device (12), means for quantifying a physical value linked to the force exerted by the user on the bearing area (20) between the rest position and the activated position, an information processing system for processing the quantified physical value and providing information on the dispensed product dose.

The invention also relates to a method for monitoring the dispensing of a complete dose during the activation of a product dispensing device (12), by means of such an assistance device (10).

The present invention relates to a medicament delivery device, comprising an outer body, a receptacle for a medicament, a needle for the administration of the medicament, an injection mechanism with an actuating mechanism for injecting the medicament into the patients body, and a needle guard for the needle. The medicament delivery device further comprising a detecting element for the detection of the orientation of the medicament delivery device, and a locking mechanism releasing the actuating mechanism, if the detecting element is in the at least first position, and locking the actuating mechanism, if the detecting element is in the at least second position, wherein the locking mechanism is controlled and/or actuated by the detecting element.

A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient to the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. In addition, the hemodialysis system includes two reservoirs which can be alternately placed in the dialysis flow path using various controllable fluid valves. The weight, and therefore the level of dialysate, of each reservoir is measured by a preferred level sensor having a lever arm, a load cell, and a tilt sensor. The load cell and tilt sensor are electrically connected to a processor for sending force and tilt measurements to the processor. The processor may analyze the tilt measurements to correct for any inaccurate measurements of the load cell caused by the tilt.

An electrically heated aerosol-generating device includes a storage portion configured to contain an aerosol-forming substrate and having a fluid permeable internal surface surrounding an open-ended passage extending through the cartridge. The device includes a housing having a cavity for receiving the cartridge, and a heater assembly positioned in the cavity. The heater assembly includes an elongate support member connected to the housing and arranged to extend into the open-ended passage of a cartridge inserted in the cavity. The heater assembly also includes a plurality of electric heaters fixed to and spaced along the length of the elongate support member.

An active injection guide concurrently monitors surface contact and an instantaneous contact force along an injection axis of an injector in order to ensure that the injector is properly positioned on a patient before an injection can be initiated.

An information collection method for an injection pen includes several steps as follows. The action of the pressing knob is sensed to determine whether the rotation information of the pressing knob is obtained. The traveling movement of the injection pen is sensed to determine whether the movement information of the injection pen is obtained. A determination is made that the traveling movement of the injection pen is conformed as an intending injection action according to the rotation information of the pressing knob and the movement information of the injection pen. When the traveling movement of the injection pen is conformed as the intending injection action, an actual injection dose that the injection content is pushed outwards from the injection pen is calculated according to the rotation information of the pressing knob. The actual injection dose is recorded.

An electrically heated aerosol-generating device includes a storage portion configured to contain an aerosol-forming substrate and having a fluid permeable internal surface surrounding an open-ended passage extending through the cartridge. The device includes a housing having a cavity for receiving the cartridge, and a heater assembly positioned in the cavity. The heater assembly includes an elongate support member connected to the housing and arranged to extend into the open-ended passage of a cartridge inserted in the cavity. The heater assembly also includes a plurality of electric heaters fixed to and spaced along the length of the elongate support member.

A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device.

Disclosed is a method and an auto-injector for administering a medicament. The auto injector comprising: a housing; a cartridge receiver configured to receive a cartridge comprising a first stopper; a drive module coupled to move a plunger rod between a retracted plunger rod position and an extended plunger rod position, the plunger rod being configured to move the first stopper; a resistance sensor configured to provide a resistance signal indicative of resistance against movement of the plunger rod; and a processing unit coupled to the drive module and to the resistance sensor. The processing unit being configured to: control the drive module to move the plunger rod towards the extended plunger rod position with a plunger rod speed; determine plunger rod position; receive the resistance signal; and control the drive module to adjust movement of the plunger rod if the resistance signal is indicative of resistance against movement of the plunger rod above a high resistance threshold, wherein the high resistance threshold is based on the plunger rod position.