An air delivery system for providing a supply of air from a source of air at positive pressure to an interfacing structure located at the entrance to the airways of a patient includes a manifold adapted to connect with the supply of positive air pressure and at least one tube connected to the manifold and adapted to deliver the supply of air to the interfacing structure. Each tube is structured to allow movement between an open phase in which the tube allows the passage of air and a collapsed phase in which the tube is collapsed. Each tube is structured such that weight of a typical patient's head against bedding apparel is sufficient to collapse the tube from the open phase to the collapsed phase.

A needle magnetizing arrangement (1) comprising a controller (4) adapted to generate a first magnetic field (F) for magnetizing a needle (2), and a magnetic field sensor (5) adapted to generate a signal based on a second magnetic field (F.sub.R) of the needle (2).

A disposable syringe set includes a syringe barrel in which a medicinal fluid inlet is formed and a plunger is fitted and coupled to an opening at the other side; a first screw-coupling portion formed on an outer circumference of the medicinal fluid inlet; a syringe needle hub in which a syringe needle is coupled to one end and an inner side at the other end is fitted and coupled to the outer circumference of the medicinal fluid inlet; and a second screw-coupling portion formed on an inner circumference of the syringe needle hub and configured to be coupled to the first screw-coupling portion. The first screw-coupling portion is formed as a female-thread-type coupling portion whose diameter is smaller than a reference diameter of the medicinal fluid inlet. The second screw-coupling portion is formed as a male-thread-type coupling portion configured to be coupled to the female-thread-type coupling portion.

A locking mechanism for an aerosol dispenser is presented having a first body structure, a second body structure rotatably attached to the first body structure, a spindle rotatably attached to the second body structure, the spindle having an actuator rotationally cooperating with the first body structure such that rotation of the first body structure relative to the second body structure causes rotation of the actuator and of the spindle, a movable element arranged around the spindle, the spindle being rotatable relative to the movable element, wherein rotation of the spindle causes movement of the movable element along the spindle from an initial position to a final position, and a locking element, wherein in the final position the movable element applies a radial force onto the locking element causing the locking element to bend in the radial direction thereby preventing rotation between the first body structure and the second body structure.

In an elongated casing, an active agent container connected to an injection needle can be shifted axially by a spring force. Auto-injectors distributed pre-filled and with the springs tensed may be provided with a needle protecting cap to ensure sterility of the needle. When the needle protecting cap is removed as preparation for using the auto-injector, a tensile force can be exerted on the active agent container. Therefore, the active agent container and needle must be prevented from being undesirably pulled forwards. At least one latching tongue prevents the active agent container from being prematurely shifted with respect to the casing, by abutting a flange arranged on a sliding sleeve accommodating the active agent container. When the auto-injector is placed onto the skin, a needle protecting tube is shifted into the casing, forcing the latching tongue away from the flange, thereby freeing the travel path for needle movement.

The invention relates to a fluid reservoir (2) for an aerosol generator (50), the fluid reservoir (2) comprising a fluid chamber (4) for receiving a fluid (6), an opening (8) for guiding the fluid (6) received in the fluid chamber (4) outside the fluid chamber (4), and a collar portion (10) surrounding the opening (8) and extending into the fluid chamber (4). A first portion (12) of the fluid chamber (4) extends along the length of the collar portion (10) in a height direction (H) of the fluid chamber (4), A second portion (14) of the fluid chamber (4) is arranged adjacent to the first portion (12) in the height direction (H) of the fluid chamber (4). A lateral extension of the first portion (12) in the directions perpendicular to the height direction (H) of the fluid chamber (4) is smaller than a lateral extension of the second portion (14) in the directions perpendicular to the height direction (H) of the fluid chamber (4). Further, the invention relates to a fluid reservoir (2′) for an aerosol generator (50), the fluid reservoir (2′) comprising a fluid chamber (4′) for receiving a fluid (6′), an opening (8′) for guiding the fluid (6′) received in the fluid chamber (4′) outside the fluid chamber (4′), a recess (9) arranged at least partly below the opening (8!) in a height direction (H) of the fluid chamber (4′), and a cover member (30′) which releasably or permanently seals the recess (9). Moreover, the invention relates to an aerosol generator (50) comprising the fluid reservoir (2, 2′).

A dispensing device is provided to dispense a designated amount of a material on every dose delivery operation. The dispensing device includes a thumb pad, a cam drum coupled to the thumb pad, and a pawl nut comprising a one-way pawl. The thumb pad may be pulled out in a direction away from a distal end of the dispensing device for setting a dose of the material to be dispensed out and may be pushed in towards the distal end for delivering the dose. The cam drum includes a plurality of linear cam profiles and a plurality of helical cam profiles that may be disposed on a surface of the cam drum. The one-way pawl may engage with a ratchet disposed at a distal end of the cam drum and may prevent a rotation of the cam drum in an undesired direction.

A drug delivery device (1), comprising a delivery unit (2) in the form of a disposable single use part and a base unit (4) in the form of a reusable part for coupling to the delivery unit (2), the delivery unit comprising a liquid flow system for pumping liquid from a drug vial or cartridge (3) received in the drug delivery device to an outlet of the device for transcutaneous administration of a liquid drug, the base unit including at least a power source and an electronic control system, the delivery unit and base units comprising a releasable locking mechanism including a locking shoulder (30) on the delivery unit that engages a complementary locking shoulder (34) on the base unit. The locking mechanism comprising an unlocking actuator that may be actuated to release the locking shoulder (30) from the complementary locking shoulder (34). The device further comprises a coupling member (8b) on the delivery unit that engages a complementary coupling member (8a) on the base unit, at least one of the coupling member and complementary coupling member comprising at least one elastic arm (10) with a protuberant portion (11) at a free end thereof, the protuberant portion (11) having a rearwardly inclined taper (13) that engages a complementary taper on a complementary protuberant latch portion (12) of the other of said coupling member and complementary coupling member, configured to provide a pulling force (F) between the base unit and the delivery unit to draw them together in a tight fit without play.

A single-use connector configured to be removably connected to a reusable connector includes a hollow, tubular housing having an open proximal side opposite a distal side along a longitudinal length of the housing and at least one guard member connected to the tubular housing. The at least one guard member is configured to transition between an open position, in which the single-use connector can be connected to the reusable connector, and a closed position in which the guard member prevents the single-use connector from being connected to the reusable connector. Disconnecting the single-use connector from the reusable connector causes the at least one guard member to transition from the open position to the closed position. A single-use disposable set (SUDS) including a single-use connector and at least use guard member for preventing reconnection of the connector to a reusable connector or fluid port is also disclosed.

A therapeutic treatment device, system and method for improving administration of a temperature sensitive drug into a tissue on the body of a patient at a drug injection site are disclosed. The device includes a treatment element with a controllable heating element in temperature communicative contact with the tissue adjacent to the drug injection site. The controllable heating element is configured to heat the tissue adjacent to the drug injection site to a controllable temperature but does not heat the injected drug above a predetermined limiting temperature, above which degradation of the injected drug may occur.