A device for adjusting the tightening angle of a needle safety protector is proposed. The device is configured to provide an injection needle in an integrated state with a needle hub for preventing reuse of the injection needle and to fasten the needle hub to a needle safety protector that is disposed of in a folded state after use, a fastening structure is improved such that rotation is possible by a predetermined angle when the needle safety protector is rotated. Accordingly, an injection is safely performed by correcting the injection needle to the reference direction. In addition, even when a syringe is assembled by deviating from a reference angle during the mass production with the automatic line, the wrong angle is corrected in use.

A drug delivery device, in particular a nebulizer or inhaler, for dispensing a fluid includes a cartridge having a collapsible container within which the fluid is disposed, a mechanism to help the collapsing process and to prevent the collapsed container from expanding again, hence preventing the forming of vapor and gas bubbles within, where the mechanism is adapted to pressurize the fluid within the container during withdrawal of the fluid.

The method and system according to preferred embodiments of the present invention allows an effective delivery of aerosolized medicament (e.g., a surfactant) to the patient's lungs. According to a preferred embodiment, the method of the present invention provides an efficient delivery of the aerosol medicament (possibly breath synchronized). A glass vial in which medicaments are usually stored and shipped is used directly as a component of the system. Its function in the system is that of an intermittently pressurized chamber that can inject the surfactant into the catheter of the atomizer device. According to a preferred embodiment the delivery can be done in phase with the beginning of each inspiration. The main elements of the system are: a source of compressed gas, the already mentioned medicament vial, a catheter, and optionally means to detect the breathing pattern and a control unit.

A method and system for detecting a limit of use of a medical device is disclosed. The method includes starting a timer of a medical device when said medical device is used for the first time, detecting the limit of use of the medical device and indicating the limit of use of the medical device. The limit of use is reached when at least one of a first criterion and a second criterion is met, wherein the first criterion is that the timer reaches or exceeds a time limit and wherein the second criterion is that at least one operation of a drive train of said medical device reaches or exceeds a limit.

A fluid connector assembly is disclosed. The fluid connector assembly includes a body portion, a plug portion located on the body portion, the plug portion comprising a fluid path, a tubing, a first end of the tubing fluidly connected to the plug fluid path, a catch feature located on a first end of the body portion and configured to interact with a reservoir, and a latching feature located on a second end of the body portion, the latching feature configured to interact and lock onto the reservoir.

A wearable infusion pump assembly. The wearable infusion pump assembly includes a reservoir for receiving an infusible fluid and a fluid delivery system configured to deliver the infusible fluid from the reservoir to an external infusion set. The fluid delivery system includes a controller, a pump assembly for extracting a quantity of infusible fluid from the reservoir and providing the quantity of infusible fluid to the external infusion set, the pump assembly comprising a pump plunger, the pump plunger having distance of travel, the distance of travel having a starting position and an ending position, at least one optical sensor assembly for sensing the starting position and ending position of the pump plunger distance of travel and sending sensor output to the controller, and a first valve assembly configured to selectively isolate the pump assembly from the reservoir, wherein the controller receives the sensor output and determines the total displacement of the pump plunger.

A device includes a housing having a first end, a second end, a first cylinder, a second cylinder parallel to the first cylinder, and a channel connecting the first and second cylinders near the second end. A piston is positioned within the first cylinder. A cartridge containing a therapeutic agent is positioned within the second cylinder. A needle hub containing a needle is positioned within the second cylinder between the cartridge and the first end. A septum is positioned at the first end. A fluid is positioned within the first cylinder. When the device is activated, the piston travels toward the second end, forcing some of the fluid to travel from the first cylinder into the second cylinder, forcing the cartridge toward the first end, causing the needle to penetrate the cartridge and the septum, and causing at least some of the therapeutic agent to extrude through the needle

An irrigation system, for irrigation of a hollow body organ, comprises a reusable part and a disposable part. The reusable part comprises a liquid container with a first opening and a first connection interface. The disposable part comprises a protective cover comprising a tubular part, a one-way valve in the tubular part, and a protective skirt connected to and encircling the tubular part. The tubular part is provided with a second connection interface which is releasably connectable to the first connection interface.

The present invention relates to a liquid pharmaceutical preparation and a method for administering the pharmaceutical preparation by nebulizing the pharmaceutical preparation in an inhaler. The propellant-free pharmaceutical preparation comprises: (a) glycopyrrolate and indacaterol maleate; (b) a solvent; (c) a pharmacologically acceptable solubilizing agent; (d) a pharmacologically acceptable preservative, (e) a pharmacologically acceptable stabilizer.

A disposable valve assembly configured for use with an endoscope is disclosed. The disposable valve assembly may include a stem comprised of thermoplastic material, a spring stanchion configured to receive the stem and allow movement of the stem in an upward and downward position relative to the spring stanchion, a spring configured to contact that spring stanchion and the stem. In some embodiments, a lubricant is disposed on the stem, the spring stanchion and/or the spring. The disposable valve assembly may also include an antimicrobial agent disposed in the lubricant, or in the thermoplastic material and/or can be coated thereon. A method for manufacturing the disposable valve assemblies for use with an endoscope may include several steps.