Systems and methods for nitric oxide generation are provided. In an embodiment, an NO generation system can include a controller and disposable cartridge that can provide nitric oxide to two different treatments simultaneously. The disposable cartridge has multiple purposes including preparing incoming gases for exposure to the NO generation process, scrubbing exhaust gases for unwanted materials, characterizing the patient inspiratory flow, and removing moisture from sample gases collected. Plasma generation can be done within the cartridge or within the controller. The system has the capability of calibrating NO and NO.sub.2 gas analysis sensors without the use of a calibration gas.

A system may include an external device and an inhaler. The external device may include a processor, a communication circuit, and memory. The inhaler may include a mouthpiece, medicament, a mechanical dose counter, and an electronics module comprising a processor and a communication circuit. The electronics module may record a dosing event when the inhaler is actuated, such as when the mouthpiece cover is opened, and send a signal indicating the dosing event to the external device. The external device may receive a mechanical dose reading of the mechanical dose counter, determine an electronic dose reading based on the signal indicating the dosing event, determine that a discrepancy between the mechanical dose reading and the electronic dose reading exceeds a threshold, and notify the user of the discrepancy, for example, by providing a notification to the user by way of a mobile application residing on the external device.

A nasal droplet delivery device and related methods for delivering precise and repeatable dosages to a subject via the nasal passageways and sinus cavities.

Methods and apparatuses for the therapeutic delivery of nicotine for smoking cessation, harm reduction and/or substitution. Furthermore, the devices and methods herein are useful as an alternative, general nicotine delivery system in place of tobacco combustion or high temperature (over 150 degrees C.) products. In addition, the methods and devices herein are useful for the therapeutic delivery of a drug, for reducing the cumulative drug dose and hence its potential toxic side effects, while increasing its neurophysiological and/or physiological effects. Moreover, the devices and methods herein are useful for addiction treatment or reduction. In certain embodiments, the methods are adaptable to a medicament delivery device that determines a sequence of drug doses to be delivered. Dose information may be used to control operation of the device.

A ligature-resistant bag hanger for supporting an intravenous (IV) bag prevents formation of ligatures over an IV pole and on the bag support hooks. Internal components of the ligature-resistant IV bag hanger are enclosed in a housing. The internal components of the ligature-resistant bag hanger include one or more bag support hooks that have an extension portion extending from an interior of the housing and that are rotatable around an axle located within the housing. In a reset position, the bag support hook(s) support(s) an intravenous bag in a saddle portion of the hook up to a threshold weight limit. In a triggered position, initiated by a downward force in excess of the threshold weight limit rotating the hook downward, the hook rotates so that an attempted ligature formed above the saddle portion of the hook is released by retraction of the saddle portion of the within the housing.

The principles and embodiments of the present invention relate to methods and systems for safely providing NO to a recipient for inhalation therapy. There are many potential safety issues that may arise from using a reactor cartridge that converts NO.sub.2 to NO, including exhaustion of consumable reactants of the cartridge reactor. Accordingly, various embodiments of the present invention provide systems and methods of determining the remaining useful life of a NO.sub.2-to-NO reactor cartridge and/or a breakthrough of NO.sub.2, and providing an indication of the remaining useful life and/or breakthrough.

Medical devices, systems, and methods related thereto a glucose monitoring system having a first display unit in data communication with a skin-mounted assembly, the skin-mounted assembly including an in vivo sensor and a transmitter. The first display unit and a second display unit are in data communication with a data management system. The first display unit comprises memory that grants a first user first access level rights and the second display unit comprises memory that grants a second individual second access level rights.

A cavity authentication system for verifying at least one feature of a user using at least one acoustic signal, including an orifice element, including at least a signal opening and a reflection opening, an acoustic wave generator (AWG), an acoustic wave sensor (AWS), at least one output waveguide, at least one input waveguide, a processor, a memory and a power supply, the AWG for producing at least one acoustic signal, the AWS for receiving at least one reflection of the acoustic signal, the output waveguide for transmitting the acoustic signal to the user, the input waveguide for receiving the reflection of the acoustic signal, the memory configured to store cavity authentication data representative of the feature, wherein the processor is configured to analyze the reflection and to compare the analyzed reflection with the retrievable cavity authentication data and to generate an indication whether the analyzed reflection matches the retrievable cavity authentication data above a pre-determined threshold.

Drug delivery systems and methods are provided for monitoring and/or tracking exposure of a drug to one or more conditions that can affect performance of the drug.

A heating device is provided that creates inhalable aerosol that includes one or more heating elements and a temporary or permanently established cavity formed by a barrier between the heating elements and the external environment that envelops the heating elements to allow the insertion and removal of consumables from the cavity and allows for the replacement of the heating elements in the device.