Methods and systems are provided for anesthetic agent leakage diagnostics. In one embodiment, a method for diagnosing leaks in an anesthetic vaporizer includes calculating a leakage rate based on measurements of an anesthetic agent level in a sump of the anesthetic vaporizer, the measurements received from a fluid level sensor at a first time and a second time, and outputting a maintenance alert responsive to the leakage rate exceeding a threshold.

An inhalation device defines a receptacle for receiving an aerosol-forming substrate containing at least one vaporizable substance; an atomizer configured to generate an aerosol from the aerosol-forming substrate; a first sensor configured to generate a first signal or first data associated with a presence of at least one chemical substance in the generated aerosol; a second sensor configured to generate a second signal or second data associated with a further characteristic of the generated aerosol or of the aerosol-forming substrate or of the at least one vaporizable substance; and at least one controller configured to separately analyze both the first signal or first data and the second signal or second data to determine first and second analysis results, and configured to determine an operation mode of the inhalation device or to determine whether to alter an operation of the inhalation device based on both the first and second analysis results.

Aspects of the present disclosure provide a smart relaxation mask configured to output a stimulus and collect biometric information while the stimulus is output to determine if the subject is paying attention to the stimulus. If the subject is not focused on the stimulus, the mask adjusts at least one of an audio, visual, or haptic output. The stimulus is adjusted in an effort to shift the subject's attention to the stimulus and away from racing thoughts.

A data collection device comprises at least two optical sensors configured to detect tick marks of a medicament dose indicator of the medicament delivery device in their respective detection areas, and a processing arrangement configured to determine a current medicament dosage programmed into said medicament delivery device based on a count of the tick marks that pass through the detection areas of the optical sensors during programming of said medicament dosage into said medicament delivery device. A direction of travel of the tick marks may be identified, to determine whether the programmed dosage is increasing or decreasing. The apparatus may be arranged to identify a baseline dosage amount using a camera image of the medicament dosage indicator, so that a starting point for the count of tick marks can be determined. The medicament delivery device may be an injector pen.

A system and methods are described for improving the management of ischemic cardiac tissue during acute coronary syndromes. The system combines a catheter-based sub-system which allows for simultaneous balloon dilation of a coronary artery and infusion of a carefully controlled perfusate during percutaneous coronary intervention. The system allows for modulation of levels of oxygen at the time of percutaneous intervention. In addition, catheters and systems are provided for administration of fluids with modified oxygen content during an intervention that incorporate upstream flow control members to compartmentalize the perfusion of the target coronary artery and the remainder of the heart.

A data collection device (20) for attachment to an injection device (1), such as an injector pen, comprises a sensor arrangement (26) to detect movement of a movable (70) of the injection device (1) relative to the data collection device (20) during delivery of a medicament by the injection device (1), and a processor arrangement (23) configured to, based on said detected movement, determine a medicament dosage administered by the injection device (1). The processor arrangement (23) may monitor the time that has elapsed since the medicament dosage was administered, and control a display (22) to show the medicament dosage (22a) and elapsed 22 time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component (70) comprises a plurality of light barrier formations. The movable component (70) may be a number sleeve that provides a visual indication of a dose programmed into the injection device (1).

Apparatus and methods are described for use with a portion of plant material that includes at least one active ingredient. A vaporizing unit includes a heating element configured to heat the plant material, and a sensor configured to detect an indication of airflow rate through the vaporizing unit. Control circuitry is configured to receive an indication of the airflow rate through the vaporizing unit, and, in response thereto, to determine a smoking profile that is desired by the user. The control circuitry drives the heating element to vaporize the active ingredient of the plant material by heating the plant material according to the determined smoking profile. The control circuitry dynamically updates the smoking profile in response to changes in airflow rate over the course of a smoking session. Other applications are also described.

A control body is coupled or coupleable with a cartridge that is equipped with a heating element and contains an aerosol precursor composition, the control body and cartridge forming an aerosol delivery device. The control body includes a control component to control the heating element to activate and vaporize components of the aerosol precursor composition. The control body also includes a gas sensor configured to detect a presence of gas in an environment of the control body, and the gas sensor or control component are further configured to control operation of at least one functional element of the aerosol delivery device in response to the presence of gas so detected.

Systems and methods are provided for anesthetic agent level sensing. In one embodiment, a system for a level sensor for an anesthetic vaporizer includes a measurement tube including a float positioned therein, a bottom portion of the measurement tube coupled to a cap having a central opening, a retaining bracket coupled to a top portion of the measurement tube, an optical sensor housed within the retaining bracket, the optical sensor including a light source positioned to emit light toward an interior of the measurement tube and a light detector positioned to receive light from the interior of the measurement tube, and an optical window housed within the retaining bracket and coupled between the optical sensor and the interior of the measurement tube.

A system and method for determining the fill volume of a fluid chamber includes a fluid injector, at least one fluid chamber in fluid communication with the fluid injector, one or more sensors positioned relative to the at least one fluid chamber and configured to detect a position of a liquid-gas interface of the fluid contained in the at least one fluid chamber, and at least one processor in communication with the sensors and the fluid injector, and configured to: determine the position of the liquid-gas interface of the fluid, calculate the volume of fluid in the at least one fluid chamber based on the position of the liquid-gas interface, and at least one of: i) display the volume of the fluid; ii) enable the fluid injector to perform an action; and iii) disable the fluid injector from performing the action.