The methods, systems and devices provided herein relate to sleep-aid. Some embodiments include a vibration source and/or a sound source. In some embodiments, the vibration source and/or sound source emit vibrations and/or sounds that stimulate a subject's vagus nerve, or another nerve, to induce sleep or relaxation in the subject.

Sensing systems, connectors, and methods include a housing, including a sensor and a locking mechanism, a junction, and a membrane. The junction includes a fluid inlet, a fluid outlet, and a receiving mechanism. The receiving mechanism is removably attachable to the locking mechanism. The membrane is disposed within the junction, and is in fluid communication with the fluid inlet and the fluid outlet. The sensor senses a property of a fluid across the membrane when the locking mechanism is attached to the receiving mechanism.

A manifold for the circulation of fluids along predetermined circulation paths or circuits, for example, for extracorporeal dialysis machines. The manifold comprises a main body with a plurality of inner channels mutually connected to define the predetermined circulation paths, the predetermined circulation paths communicating with the exterior of the main body by way of at least one inlet and at least one outlet adapted to be connected to component parts and/or tubing of an extracorporeal dialysis machine, and dialysis machine equipped with the aforesaid manifold.

A drug delivery device including a reservoir configured to contain a fluid to be delivered by advancing a piston in the reservoir at an advancement speed defining a delivery rate for the medicament. The device further includes an electric motor configured to drive the delivery mechanism by rotation to advance the piston at the advancement speed. The device further includes a control unit that controls a rotational speed and an on state/off state of the electric motor. The control unit determines rotational speed of the electric motor based on a back-electromagnetic force signal provided from the electric motor while operating in a monitoring mode. The control unit controls the rotational speed of the electric motor such that a back-emf signal can be detected in the monitoring mode. The control unit modulates the on state/off state of the electric motor to adjust the delivery rate of the medicament.

In one embodiment, a fluid dynamics system includes a solenoid valve including a valve body, which includes a valve cavity having a direction of elongation, a first channel, and a second channel, a solenoid coil disposed in the valve body around the valve cavity, and a plunger comprising a magnetic element and configured to move back-and-forth along the direction of elongation between a first position and a second position in the valve cavity, selectively opening the first channel and closing the second channel when the plunger is in the first position, and closing the first channel and opening the second channel when the plunger is in the second position, and a controller configured to control the solenoid coil to selectively move the plunger between the first position and the second position, and to selectively maintain the plunger in the first position and the second position.

A peritoneal dialysis cassette that uses an external pump to drive fluid through the peritoneal dialysis cassette is provided. The peritoneal dialysis cassette can include two inlet/outlet ports connected to an inlet and outlet of the external pump. The external pump drives fluid through fluid passages in the peritoneal dialysis cassette connecting a plurality of other inlet/outlet ports, with one or more valves usable to selectively direct fluid through the peritoneal dialysis cassette.

A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

A dosage sensing module for or in a pen drug delivery device and comprising a power source unit, a processor unit and a dosage sensor unit with a first sensor part adapted to be fixed to a part not rotating during dose expelling and comprising a flexible printed circuit board sheet on which a pattern of individual electrical conductive sensor areas are arranged. The sensor unit further comprises a second sensor part adapted to be fixed to the piston rod to follow the rotation thereof during dose expelling. The second sensor part comprises individual structures that together with the conductive sensor areas are adapted to, upon relative rotational movement between the first and second sensor part, provide electrical signals to a processor unit indicative of the relative rotational position between the first and second sensor part.

A method of fit testing includes providing a respirator; providing a sensor having a sensing element removably positioned substantially within an interior gas space of the respirator; providing a reader configured to be in wireless communication with the sensor; positioning the respirator over a mouth and a nose of a user while the sensor is positioned substantially within an interior gas space of the respirator; and observing respirator fit assessment data communicated from the sensor to the reader.

The present invention relates to a suction instrument, more particularly a bipolar mapping suction instrument, for surgical purposes and to a system for suctioning fluids and tissue and for monitoring nerve tissue. The suction instrument comprises a cannula unit, which comprises an electrically conductive outer cannula tube, an electrically conductive inner cannula tube, and insulation. The electrically conductive inner cannula tube is electrically connected to a first pole of the bipolar electrical connection of the second interface. The electrically conductive inner cannula tube is arranged concentrically in the outer cannula tube which optionally can be insulated from the exterior. The electrically conductive inner cannula tube is mechanically connected to the handpiece and/or the first interface. The electrically conductive outer cannula tube is electrically connected to a second pole of the bipolar electrical connection of the second interface. The insulation is concentrically arranged between the outer cannula tube and the inner cannula tube. The insulation is configured to fully electrically isolate the outer cannula tube and the inner cannula tube in relation to one another.