Devices for delivering a controlled concentration of an agent are provided. The device includes a reservoir for the agent and a flow control portion operably connected to the reservoir. The device also includes a valve for releasing the agent from the flow control portion and a pump for flowing air to mix with the agent released by the valve and for flowing the agent and air mixture out of the device. Methods of delivering a vaporized agent to a subject are also provided. The methods include storing a liquid agent in a reservoir of a device and flowing the agent into a flow control chamber to change the agent to a gas. The methods also include mixing the agent in gas form with air and flowing the agent and air mixture out of the device to be delivered to a subject.

A dressing for treating tissue with negative pressure is provided herein comprising a composite of dressing layers, including a release film, a perforated coated polymer film, a manifold, and an adhesive cover. Additionally, a method of manufacturing the dressing may comprise applying a cross-linkable polymer to a polymer film, curing the cross-linkable polymer to a gel layer to form a coated polymer film, and perforating the coated polymer film to form fluid restrictions, such as slits and/or slots, though the coated polymer film.

Apparatus is disclosed for ventilation using an airbag, which may also be operable manually. The apparatus comprises: means providing or penetrable to form an aperture in the airbag; retractable means provided separately from the airbag, for extending in the airbag; fixing means for fixing, by an operator, an end of the retractable means to the airbag via the aperture; actuation means, for repeatedly retracting the retractable means at least partially through the aperture in the airbag to collapse the airbag, and for enabling expansion of the airbag to an expanded state; and connecting means for connecting the actuation means to the airbag and for preventing environment egress of gas from within the airbag between the aperture and the actuation means.

A negative pressure wound therapy device can include a negative pressure source configured to be connected, via a fluid flow path, to a wound, a valve positioned in the fluid flow path and configured to, in an open state, permit supply of negative pressure from the negative pressure source upstream of the valve and, in a closed state, block supply of negative pressure from the negative pressure source upstream of the valve, a flow restrictor positioned in the fluid flow path, and a pressure sensor configured to measure a pressure differential across the flow restrictor. The device can include control circuitry configured to, in a normal operational mode, cause the valve to be in the open state and, in a test mode, perform at least one of a leak test, a flow test, or an excessive pressure test.

An infusion system and method configured to identify a break in static friction between a plunger and an infusate cartridge during an infusion of infusate for the purpose of providing a more consistent flow of infusate and promoting a more efficient use of energy. The infusion system and method can include monitoring of force between a drive mechanism and the plunger for a decrease in a rate of the force over time during actuation of the drive mechanism, thereby indicating a break in static friction between the plunger and the cartridge, and determining a low power consumption sleep duration based on an advancement of the actuator following the break in static friction.

System for assisting a patient in speaking, comprising at least one ventilation apparatus and a patient interface, the ventilation apparatus comprising at least one controllable respiratory gas source and being designed to identify two or more respiratory phases, at least inspiration and expiration, of the patient, and the patient interface having at least one speaking tube and a respiratory tube and being configured to conduct speaking gas to the patient via the speaking tube and to conduct respiratory gas to and/or from the patient via the respiratory tube. The system is configured to provide speaking gas to the patient at least temporarily in a speaking mode in order to enable speaking.

A ventilation device comprising a controllable respiratory gas source and a programmable control unit being configured to perform the following: determining the respiratory gas flow, which is used to determine whether an inspiration or an expiration is present, regulating the pressure for an inspiration (IPAP) and an expiration (EPAP), wherein the control unit determines a typical expiration time over n breaths, the control unit lowers the pressure from the IPAP to the EPAP taking into account the typical expiration time in such a way that the pressure drop to the EPAP is already reached to the extent of at least 85% after a proportion of the typical expiration time in the range of 40-60% of the typical expiration time, the EPAP after completion of the pressure drop being predefined until the end of the typical expiration time.

A supply arrangement (100) and a process supply a medical device (50, 90) with a supply gas mixture. The supply gas mixture includes a carrier gas and an anesthetic and is generated by an anesthetic dispenser (3). A carrier gas mixing unit (9) generates the carrier gas from at least two carrier gas components. A carrier gas switch having a regular outlet and a discharge outlet selectively directs carrier gas components to the carrier gas mixing unit or to a discharge line (35). A gas mixture switch (6), having a regular outlet (41) and a discharge outlet (42) selectively directs the supply gas mixture to the medical device or to the discharge line (35). An anesthetic concentration sensor (5.1, 5.2) measures a concentration of anesthetic in the generated gas mixture. A control unit (2) controls the gas mixture switch based on measured concentration within or outside a predefined range.

An inhalation device defines a receptacle for receiving an aerosol-forming substrate containing at least one vaporizable substance; an atomizer configured to generate an aerosol from the aerosol-forming substrate; a first sensor configured to generate a first signal or first data associated with a presence of at least one chemical substance in the generated aerosol; a second sensor configured to generate a second signal or second data associated with a further characteristic of the generated aerosol or of the aerosol-forming substrate or of the at least one vaporizable substance; and at least one controller configured to separately analyze both the first signal or first data and the second signal or second data to determine first and second analysis results, and configured to determine an operation mode of the inhalation device or to determine whether to alter an operation of the inhalation device based on both the first and second analysis results.

An apparatus for extracorporeal treatment of blood (1) has a supply line (2), a waste line (13) and an ultrafilter (19; 70) inserted in the supply line (2). An air inlet line is connected to the first chamber (21; 72) of the ultrafilter (19; 70) and a pressure sensor (41) configured for detecting pressure in the waste line (13). A controller (50) is configured to carry out, with the hydraulic circuit (100) in by-pass configuration, an integrity test procedure for detecting if the ultrafilter membrane has multiple or single fiber breaks. A method of testing the ultrafilter (19; 70) is also disclosed.