The present invention discloses a multifunctional temperature self-regulating multilayer film, from outside to inside comprising at least: a carrier layer (1) loaded with functional material, and a thermal-insulation layer (2) directly contacted with the skin (4); wherein the carrier layer (1) loaded with functional material has a sealed cavity sealed with a flexible water-impermeable material, the sealed cavity is at least loaded with a refrigerating or heat-generating chemical material (11); wherein thermal-insulation layer (2) is made of a material having waterproof and thermal-insulation properties. The present multilayer film can be manufactured into a face mask or eye mask for use on facial skin.

The present disclosure relates to aerosol delivery devices comprising a power unit and a cartridge that is configured for engagement with the power unit. In particular, the cartridge can be configured for rotation about a longitudinal axis thereof so as to be insertable into a chamber of the power unit in a plurality of different orientations. Further, the aerosol delivery device can include processing circuitry that can be configured for detection of the cartridge orientation and execution of a control function assigned to the respective orientation.

An injection tool and associated methods are shown. Example tools and methods described provide cooling to numb a local area prior to an injection. The local numbing can be used to reduce or eliminate pain associated with the subsequent injection. In selected examples, circuitry and one or more sensors are used to calculate an appropriate contact time of a heat sink with the local region to best provide a desired amount of numbing.

An embodiment includes a cardioplegia delivery system having a console, controller, and disposables. The system aides the perfusionist in cardioplegia delivery to the patient during Cardiopulmonary Bypass Surgery. The console, in conjunction with the disposables, combines blood from the heart-lung machine and crystalloid from the IV-bag in a specified ratio and then adds in a drug (arrest agent and/or additive). The electro-mechanical console incorporates a blood/crystalloid pump, temperature controllable water circulation system, pressure and temperature monitors, a sensor interface with the disposables, an arrest agent pump, an additive pump and ultra-sonic air detection sensors. The system monitors and controls the blood-crystalloid ratio, drug concentration, flow rate, pressure, temperature, and delivery route of the cardioplegia solution delivered to the patient. The system is a software-controlled system with a graphical user interface controller. The controller is utilized to initiate/stop cardioplegia delivery, monitor delivery parameters and view/save relevant case information and data.

The invention relates to an injection device which includes a handle and a guard which together enclose a movable cartridge which can contain liquid material to be injected, and further enclose a movable injector that includes a needle, the needle being attached to a housing where the housing is attached to the cartridge, the device also including a delivery mechanism whereby the needle is moved from a retracted to an extended position, and independently the volume of the chamber may be adjusted to expel the contents thereof through the needle and into a subject in need thereof. The injection device may be communicatively connected to a control unit so as to provide a dermal injection system.

An anti-germ breathing device is provided for a user, the device including a heating element housing an electric conduit; a one-way valve in communication with the heating element, the one-way valve having a first air filter and being structured and disposed for permitting entry of air from the atmosphere into the heating element when the user inhales through an inhale tube; a suction electric switch structured and disposed for connecting a battery with the electric conduit for heating the electric conduit when the user inhales; a cooling element housing a plurality of bulkheads; an air tube in fluid flow communication with each of the heating element and the cooling element; the plurality of bulkheads being sized and configured for evenly distributing air so that the air cools before it is inhaled by the user; and the inhale tube being in fluid flow communication with the cooling element such that the user inhales cooled

An apparatus and method for the controlled acceleration, and/or retardation of the body's inflammatory response comprises a foam pad for insertion into a wound site, a drape covering the foam pad, and a thermal control element configured to be placed proximate the wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The thermal control element has a pair of flexible sheets for receiving a thermally conductive fluid.

A system is provided for dispensing a fluid. The system has a housing having a fixation means to a user and an orientation element; the cartridge formed so as to be held in a given orientation by the orientation element with respect to the housing; and control means to activate the cartridge to eject a fluid. In one aspect, the system is a emergency rescue fluid(s) transdermal delivery system which includes a removable, single use emergency rescue fluid(s) dispensing cartridge, a wearable device into which the emergency rescue fluid(s) dispensing cartridge uniquely, matingly and removably inserts. The system includes a communication pathway between the wearable device and at least one other cloud network node, and/or at least one communication pathway between the wearable device and at least one GPS network node. In another aspect, the system dispenses a perfume or other fragrance.

According to one embodiment, a CPAP device includes a housing, a fan, and a sound absorbing material. The housing has a first air inlet and a first air outlet, and a flow channel guiding air sucked through the first air inlet to the first air outlet. The fan has a second air inlet and a second air outlet, the second air inlet is disposed in the direction intersecting the flow channel, and the second air outlet is disposed in the direction along the flow channel. The sound absorbing material is provided with a recess constituting a part of the flow channel and facing the second air inlet of the fan, the recess having a diameter which is greater than a diameter of the second air inlet of the fan and which is equal to or smaller than the width of the flow channel.

A preferred method to obtain painless or near painless needle 8 penetration is disclosed to be in the following manner: Applying electric current using a TENS device simultaneously with tapping the injection site for 30 to 60 seconds at a rate of about one strike per second, followed by a rapid needle 8 penetration into the skin 2.