An adsorber for a gas concentrator includes an adsorbent material having adsorbent particles and a vessel housing the adsorbent material. The vessel includes a vessel wall having a non-circular cross section and at least one stiffening support. A combination of a thickness of the vessel wall and a stiffness of the stiffening support is sufficient to limit deformation of the vessel wall to at least one of less than 0.1 mm and less than 25% of an average diameter of the adsorbent particles under a pressure swing of at least 30 psi within the vessel.

A method of operating a compressor system includes determining an efficiency of a compressor configured to operate at a plurality of output flow settings, including one or more of measuring, calibrating, calculating, or modeling motor efficiency over a range of supply voltage and pulse width modulation duty cycle combinations, each combination including a supply voltage of a plurality of supply voltages and a pulse width modulation duty cycle of a plurality of pulse width modulation duty cycles. The method further includes selecting a supply voltage and a pulse width modulation duty cycle for use at at least one output flow setting of the plurality of output flow settings based on the determined efficiency of the compressor, generating the selected supply voltage by maintaining, reducing, or increasing a nominal supply voltage, and applying the selected pulse width modulation duty cycle.

A compressor assembly for a portable oxygen concentrator includes a first compressor chamber having a first connector, a second compressor chamber having a second connector, and a tube having a first end having a first connection interface configured to connect to the first connector and a second end having a second connection interface configured to connect to the second connector. The first connection interface is shaped to maintain the connection between the first connector and the first connection interface in a fixed orientation and the second connection interface is shaped to maintain the connection between the second connector and the second connection interface in a fixed orientation. One or more of the first connector, the second connector, and the tube are compliant.

A portable apparatus to warm a stream of biocompatible fluid prior to introduction into a patient comprises a heat exchanger base with a first side and a second side, a gas chamber cover coupled to the first side to form a gas chamber therebetween, a fluid warming chamber cover coupled to the second side to form a fluid warming chamber therebetween, an air-fuel mixing chamber with an outlet feeding an inlet to the gas chamber, a catalyst member disposed within a catalyst compartment of the gas chamber to receive an air-fuel mixture from the inlet to the gas chamber, a tortuous pathway between the catalyst compartment and an exhaust port of the gas chamber, an air mover to receive ambient air and discharge air into the air-fuel mixing chamber, and a fuel storage tank connected to feed a stream of fuel gas to the air-fuel mixing chamber.

Methods and apparatus provide automated circuit disconnection monitoring such as for a respiratory apparatus or system. Disconnection of a patient circuit, including a patient interface and air delivery circuit, may be detected and a message or alarm activated. In some versions, detecting occurrences of circuit disconnection event(s), such as by a processor, may be based on an instantaneous disconnection parameter as a function of a disconnection setting. The disconnection setting may be determined based on patient circuit type. The instantaneous disconnection parameter may be determined from detected pressure and flow rate, and may be, for example, a conductance value or an impedance value. Disconnection events may be qualified by one or more detected respiratory indicators. In some cases, instantaneous impedance or conductance may be used to assess re-connection of a patient circuit, detection of flow starvation, determine breath shape for triggering and cycling and to detect patient or circuit obstructions.

A Thermally Isolated Blood Carrier Tray includes a main panel having a plurality of thermally isolated compartments attached thereto. The thermally isolated compartments are arranged in two separate matrices having a plurality of column and rows. Each thermally isolated compartment is thermally isolated from an adjacent thermally isolated compartment. Each thermally isolated compartment maintains its own heat transfer rate without being affected by an adjacent thermally isolated compartments heat transfer rate. The placement of several different storage units having different temperatures into the Thermally Isolated Blood Carrier Tray does not affect the heat transfer rate of any one storage unit in a thermally isolated compartment. The Thermally Isolated Blood Carrier Tray provides a steady and even heat transfer from the storage unit to bring the storage units to an appropriate temperature for storage or transportation.

A chilled-air inhaler device for the alleviation of respiratory symptoms includes a body containing a hollow chamber through which air is forced or drawn past at least an air-chilling surface. In an embodiment the air-chilling surface may include water ice. Connected to the body and hollow chamber at one end is a mouthpiece including an opening that connects from environmental air outside of the hollow chamber to the hollow chamber. Connected to the hollow chamber at a second end is an inlet which connects to a source of air. In an embodiment, the inlet may connect to an external device such blower or nebulizer.

A method of treating disorders in a human or animal subject may include heating a material containing a compound to a first temperature to form a heated volume of the material. The method may additionally include heating the heated volume to a higher second temperature to form a dose of vapor including the compound. The method may also include administering the dose of vapor to the subject to treat disorders such as pain. The method may further include pre-heating the material to a preliminary temperature prior to the heating to the first temperature. The heating and pre-heating may be performed with a capsule including two covering layers, each including an electrically conductive material, configured to hold the material therebetween and to generate heat by resistive heating.

Devices and method for warm gas therapy is provided. Device comprises a gas warmer assembly to warm a first gas to a temperature in a first temperature range to obtain warm first gas. The device comprises a first delivery unit that can deliver the warm first gas to a main treatment chamber which encloses a sub-treatment chamber to retain heat therein. A second delivery unit can receive a therapeutic gas from a gas supply. The second delivery unit comprises a first portion and a second portion. The first portion substantially passes through the first delivery unit and therapeutic gas in the first portion is warmed by the warm first gas. The second portion delivers the warm therapeutic gas to a sub-treatment chamber. The sub-treatment chamber encloses a body part of a patient.

Provided herein are embodiments related to metered dose inhalers and formulations for such inhalers. In some embodiments, the inhalers are configured so as to allow a more comfortable experience for the subject receiving the formulation. In some embodiments, the formulation comprises various ingredients, such as terpenes and/or waxes, which can further enhance the level of comfort for the subject receiving the formulation.