A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

The present invention provides a two-step auto-injection apparatus consisting of a housing, a protective sleeve cylinder, a pre-filled injection assembly and a drive feedback apparatus, wherein the pre-filled injection assembly is loaded into the housing, and the protective sleeve cylinder covers a needle of the pre-filled injection assembly, so that the protective sleeve cylinder directly contacts an injecting portion and the function of injection can be realized by pressing to trigger the drive feedback apparatus during use, thereby facilitating quick operation with a needle tip hidden in the whole process; the drive feedback apparatus of a piston in a needle cylinder is driven to combine a release mechanism with an ejection mechanism and a feedback mechanism, and the release mechanism is triggered by pressing the protective sleeve cylinder, so that the ejection mechanism is released, and the ejection mechanism interacts with the feedback mechanism in a form of collision, for example, to generate a sound signal and/or a haptic signal in the moment of release for prompting a patient to begin an injection; when the ejection mechanism finishes movement, the ejection mechanism interacts again with the feedback mechanism in the form of collision, for example, to generate the sound signal and/or the haptic signal for promoting the patient to finish the injection.

Methods and systems for monitoring the status and usage of a metered dose inhaler (MDI) and communicating status, usage, and guidance information to a user of the MDI and to a mobile computing device are presented herein. An IMD includes a dosage dispense detection device, an accelerometer, and a visual transducer, an audio transducer, a haptic transducer, or any combination thereof. The dosage dispense detection device detects when a user applies a compressive force across the IMD. The accelerometer measures a shaking of the IMD by a user before self-administering a dose. The IMD determines whether the medicine is adequately shaken by the user, and if so, communicates an indication to the user that the pressurized canister of medicine is ready for dosage. In another aspect, the IMD communicates a sequence of indications that mark each transition of a dosage regimen plan to self-administer a dosage of medicine.

An aerosol delivery device is provided that includes at least one housing structured to retain an aerosol precursor composition. The device includes an atomizer, and a microprocessor configured to operate in an active mode in which the control body is configured to control the atomizer to activate and produce an aerosol from the aerosol precursor composition. And the device includes a heart rate monitor including a plurality of biopotential electrodes affixed to the housing and configured to obtain biopotential measurements from a user, and including signal conditioning circuitry configured to produce an electrocardiogram signal from the biopotential measurements. The microprocessor is coupled to the signal conditioning circuitry and further configured to control operation of at least one functional element of the aerosol delivery device based on the electrocardiogram signal or a heart rate of the user calculated therefrom.

An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.

An injection device includes a housing; a receptacle for injection fluid; a dosing piston to press out the injection fluid; a feed part connected to the dosing piston via a first threaded connection; a slide having a thread of a second threaded connection; and, a setting part having a thread of a third threaded connection and configured to set an amount of injection fluid to be dispensed. The setting part moves in the distal direction by virtue of the third threaded connection when the amount of injection fluid to be dispensed is being set. The setting part can move in the proximal direction when the injection fluid is pressed out. A latching unit defines a latching position of the setting part and acts between the setting part and housing. Each latching position has an unequivocal rotational position of the setting part in relation to the housing assigned thereto.

In various embodiments, a caregiver module is provided for use with a patient medical device, including a sensor to obtain a sensor signal related to the use of the patient medical device; an analog-to-digital converter to convert the sensor signal to corresponding sensor data; and a controller to transmit the sensor data to a wearable device, wherein the sensor data is transmitted in the same form as created by the converter. Various embodiments provide a wearable device for processing sensor data received from the caregiver module, including: memory storing processing instructions for interpreting sensor data of multiple types; and a processor to: receive configuration information associated with the caregiver module, receive sensor data of a first type from the caregiver module, and execute the processing instructions based on the configuration information, wherein the configuration information alters the operation of the processing instructions to interpret sensor data of the first type.

On-demand, hand-held vaporizer that operates primarily by convection. The vaporizer is configured to permit very rapid (e.g., within a few seconds) heating of air drawn through an oven chamber to a predetermined or selectable vaporizing temperature to vaporize a material (e.g., loose leaf plant material, etc.) that is held in the oven chamber. The vaporizer provides efficient transfer of air being heated as well as rapid delivery of vaporizable material to a user.

A method for assembling a drug delivery device that includes mounting a cartridge with a bung, the mechanism, the plunger and the spring within a housing such that a spring biases a plunger in a dispensing direction and that a drum and/or the release member is attached to the plunger attaching a tool with torque measurement capability to the drum or a release member of a dose mechanism in a state where at least one housing part is detached from further housing part; setting a dose by rotating the dose setting member in a first direction, activating a trigger and monitoring the torque applied to the drum or the release member; releasing the trigger upon detection of a predetermined change in the torque measured by the tool; and releasing the tool and closing the housing.

The present disclosure relates to a drive mechanism which is suitable for an injection device, especially a drug delivery device. The mechanism comprises a housing having a longitudinal axis defined by a compartment for receiving a cartridge, a plunger suitable for acting on a bung of a cartridge retained in the housing, a strained pressure spring arranged between the housing and the plunger, a retaining member coupled to the plunger, and a release member operable between a first state, in which the release member constrains the retaining member to the housing, and a second state, in which the release member is movable relative to the housing.