The present invention relates to immune-stimulating compositions comprising an immunestimulating compound covalently or non-convalently linked to glycogen-based nanoparticles. The immune stimulating compound may be a TLR agonist, dietary nucleotide, or combination thereof. The compositions can elicit a stronger, more robust, localized (intestine) and systemic immune response when delivered orally to aquatic species, than non-glycogen bound agonists and/or molecules.

A pet food including a base material (10), and a grain (20) fixed on a surface of the base material (10), in which a particle diameter of the grain (20) is 0.5 to 20 mm.

A pet food including a base material (10), and a grain (20) fixed on a surface of the base material (10), in which a particle diameter of the grain (20) is 0.5 to 20 mm.

It relates to a food-grade coated particle comprising: a) a core that comprises a (C.sub.4-C.sub.12)polycarboxylic acid; and b) a coating that comprises: (i) an alkali metal salt of a (C.sub.4-C.sub.12)polycarboxylic acid wherein at least one carboxylic group of the (C.sub.4-C.sub.12)polycarboxylic acid is in the acid form, and at least one carboxylic group of the (C.sub.4-C.sub.12)polycarboxylic acid is in the salt form, and (ii) a film-forming agent; wherein the weight ratio between (i) and (ii) is from 20:80 to 40:60. It also relates to processes for the preparation of these food-grade coated particles, to their use as food additives, as well as to foodstuffs comprising them.

It relates to a food-grade coated particle comprising: a) a core that comprises a (C.sub.4-C.sub.12)polycarboxylic acid; and b) a coating that comprises: (i) an alkali metal salt of a (C.sub.4-C.sub.12)polycarboxylic acid wherein at least one carboxylic group of the (C.sub.4-C.sub.12)polycarboxylic acid is in the acid form, and at least one carboxylic group of the (C.sub.4-C.sub.12)polycarboxylic acid is in the salt form, and (ii) a film-forming agent; wherein the weight ratio between (i) and (ii) is from 20:80 to 40:60. It also relates to processes for the preparation of these food-grade coated particles, to their use as food additives, as well as to foodstuffs comprising them.

Described are stable, durable granules with active agents, which have consistently low internal water activity, and methods for making such granules. The granules are particularly suitable for inclusion in steam treatment processes, including pelleting and tableting processes and steam processing of feed, without appreciable loss of active agent activity. The granules can be manufactured using humid processing air without compromising the stability of the active agents

Described are stable, durable granules with active agents, which have consistently low internal water activity, and methods for making such granules. The granules are particularly suitable for inclusion in steam treatment processes, including pelleting and tableting processes and steam processing of feed, without appreciable loss of active agent activity. The granules can be manufactured using humid processing air without compromising the stability of the active agents

The present disclosure relates to the isolation, identification and characterization of novel sporeforming probiotic strain(s) with NSPase (Non-Starch Polysaccharides-active hydrolases) activity isolated from fish gut microbiota, methods and uses thereof. The sporeforming probiotic strain(s) with NSPase activity now disclosed are able of producing carbohydrate-active enzymes (CAZymes) that hydrolyse non-starch polysaccharides (NSPs) and accesses their potential as probiotics (PRO) for use in particular in aquafeeds.

The present disclosure provides compositions and methods of using such compositions that reduce the incidence of, duration of, frequency of, or severity of clinical signs associated with or caused by pathogen infection. Representative pathogens include Streptococcus, Fusobacterium, Escherichia, and Arcanobacterium. In general, the composition includes a quantity of at least one Bacillus species.

Disclosed embodiments concern a composition and/or combination, and a method of administering the same as a feed, or to supplement the feed of, aquatic animals, particularly for aquaculture. Disclosed composition and/or combination embodiments may comprise glucan, silica, mineral clay, mannans, yucca, quillaja, a probiotic, and/or an adhesive agent. The adhesive agent may be selected particularly to facilitate administration to aquatic species. In certain embodiments the adhesive agent comprises an oil, such as soy oil, or a syrup, such as molasses, or combinations thereof. In some embodiments the composition and/or combination may further comprise polyphenol, an antimicrobial, and/or a vaccine. Also disclosed is a method for promoting growth and/or immune function in aquatic animals.